Product Name: Propylene Glycol t-Butyl Ether
Synonyms: 1-Butoxy-2-propanol tert-, PTB; t-butyl propylene glycol ether
Chemical Formula: C7H16O2
Molecular Weight: 132.2 g/mol
CAS Number: 57018-52-7
Intended Use: Solvent in coatings, cleaning agents, ink formulations
Manufacturer Details: Contact supplier for site-specific production info, technical support, and emergency hotline numbers
Emergency Phone Number: Refer to the supplier or regional poison information center for immediate response
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 3), Specific organ toxicity (single exposure, Category 3, narcosis)
Signal Word: Warning
Hazard Statements: Causes eye irritation, may cause drowsiness or dizziness, can dry or crack the skin if handled repeatedly, not classified as acutely toxic through oral or dermal route
Pictogram: Exclamation mark
Precautionary Statements: Avoid breathing mists and vapors, wear protective clothing, wash hands after handling, in case of inadequate ventilation use respiratory protection, avoid release into the environment
Route of Entry: Inhalation, skin and eye contact, accidental ingestion
Symptoms of Exposure: Throat irritation, headache, dizziness, mild dermatitis with repeated contact
Main Component: Propylene Glycol t-Butyl Ether: 99% or greater by weight
Impurities: Trace amounts (<0.1%) of related ether alcohols
Stabilizers/Preservatives: None commonly required for this solvent
Other Additives: Not applicable in standard distributions
EC Number: 260-964-7
Inhalation: Move to fresh air quickly, seek medical attention if not recovering, keep person at rest and warm, provide oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, seek medical advice in case of persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if easy, immediately continue rinsing for at least 15 minutes, obtain medical attention
Ingestion: Rinse mouth, do not induce vomiting, never give anything by mouth to an unconscious person, get medical help without delay
Most Important Symptoms: Headache, dizziness, mild drowsiness, transient skin redness, tearing or stinging in the eyes
Note to Physicians: Treat symptomatically, monitor for respiratory distress, consider observation for delayed pulmonary effects
Suitable Extinguishing Media: Foam, carbon dioxide, dry chemical, water fog
Unsuitable Media: Do not use a direct watery jet which may spread burning liquid
Flammability: Slightly flammable liquid, emits toxic vapors under fire conditions
Special Protective Equipment: Full bunker gear, self-contained breathing apparatus recommended
Hazards from Combustion Products: Carbon monoxide, carbon dioxide, possible aldehydes
Special Precautions: Containers may rupture when heated, cool exposed containers with water spray, prevent run-off entering drains
Explosion Risk: Vapors form explosive mixtures with air at high concentrations and in poorly ventilated areas
Personal Precautions: Wear full PPE including gloves, goggles, and protective clothing, avoid ocular and dermal exposure, evacuate unnecessary personnel from area
Environmental Precautions: Prevent further leakage or spillage if safe, do not let product enter drains, ditches, surface water or groundwater
Containment Methods: Stop leak at source, use inert absorbent materials (sand, earth, vermiculite), do not touch spilled material
Cleanup Methods: Scoop up liquid and absorbed material, transfer to approved containers, keep area ventilated
Delta Procedures: Dispose of in accordance with local, national, and international regulations
Decontamination: Rinse spill area with water after material is removed, avoid excess water use
Handling Recommendations: Use in well-ventilated locations, avoid inhaling vapors and prolonged skin contact, wash thoroughly after use, keep away from sources of ignition, no smoking or open flames
Technical Measures: Utilize closed transfer systems where feasible, utilize explosion-proof electrical equipment
Storage Conditions: Keep containers tightly closed in a cool, dry, well-ventilated space, store away from oxidizers, acids, and foodstuff, protect from frost and sunlight
Incompatible Substances: Strong oxidizing agents, mineral acids, strong bases
Packaging Materials: Use metal or high-density polyethylene drums, not to be stored in mild steel for extended periods
Specific Use Guidance: Reserved exclusively for industrial or laboratory application, avoid home or non-technical consumer use
Occupational Exposure Limits: No established international TLV, ACGIH recommended guideline of 50 ppm as an 8-hour TWA
Engineering Controls: Local exhaust systems, lab fume hoods, mechanical ventilation as required to avoid vapor build-up
Personal Protective Equipment: Solvent-resistant nitrile gloves, chemical splash goggles or face shields, anti-static protective suits
Respiratory Protection: In case of inadequate ventilation, wear organic vapor respirators
Environmental Exposure Controls: Prevent release into open environment or sewage, use appropriate spill barriers
Hygiene Measures: Do not eat or drink nearby, always wash hands before breaks and after use
Appearance: Clear, colorless to faintly hazy liquid
Odor: Faint ether-like, slightly alcoholic
Odor Threshold: Low, may be unnoticeable at hazardous concentrations
pH (at 20°C): Neutral
Melting Point/Freezing Point: Approximately -75°C
Initial Boiling Point and Range: 144°C to 146°C
Flash Point: 57°C (closed cup)
Evaporation Rate: Slower than ethyl ether
Flammability (solid, gas): Not applicable (liquid)
Upper/Lower Flammability Limits: 1.1 - 8.5% v/v in air
Vapor Pressure (25°C): 2.2 mmHg
Vapor Density: 4.6 (air=1)
Relative Density: 0.89 – 0.92 (water=1)
Solubility in Water: Moderate (up to 24 g/L at 20°C)
Partition Coefficient (n-octanol/water): 0.56 – moderate mobility, low accumulation in organisms
Autoignition Temperature: 243°C
Viscosity: 3.1 mPa.s (25°C)
Chemical Stability: Stable in normal handling and storage at ambient temperature
Reactivity: No hazardous reactions with ordinary building materials, may react with oxidizers exothermically
Conditions to Avoid: Heat, sparks, open flames, high temperature storage, direct sunlight
Incompatible Materials: Strong acids or bases, reducing or oxidizing agents, strong alkali metals
Decomposition Products: Toxic gases such as carbon monoxide and carbon dioxide, traces of aldehydes
Polymerization: No dangerous polymerization expected
Acute Toxicity: Oral LD50 (rat): > 2000 mg/kg, Dermal LD50 (rabbit): > 2000 mg/kg, not likely to be acutely harmful by ingestion or skin absorption
Skin Corrosion/Irritation: Mildly irritating to skin on repeated or prolonged exposure
Eye Damage/Irritation: Causes moderate eye irritation upon contact
Respiratory Sensitization: Not classified as a respiratory sensitizer
Germ Cell Mutagenicity: Not classified as mutagenic based on available data
Carcinogenicity: Not listed by IARC, NTP, OSHA or the EU as carcinogenic
Reproductive Toxicity: No adverse effect levels observed in multi-generation studies in rodents
STOT (Single Exposure): Vapors can cause dizziness and drowsiness at high levels
STOT (Repeated Exposure): No systemic toxicity observed in repeated dose animal studies
Aspiration Hazard: Not an aspiration hazard based on viscosity and physical properties
Ecotoxicity: Moderately toxic to aquatic life, 96 hour LC50 for fish ~250 mg/L, EC50 for invertebrates ~220 mg/L
Persistence and Degradability: Biodegradable under aerobic conditions, estimated >85% removal in standard tests
Potential for Bioaccumulation: Low, log Kow <1, low potential for persistent accumulation in biota
Mobility in Soil: Highly mobile due to water solubility; may leach into groundwater if released on land
Other Adverse Effects: Not expected to contribute to ozone depletion or global warming
Ecotoxicology Comments: Avoid release to the environment, observe regional discharge limits
Waste Disposal Methods: Dispose as special chemical waste; must not drain to sewer or surface water, use licensed waste contractor
Product Disposal: Incinerate in hazardous waste facility, thermal treatment with energy recovery preferred
Packaging Disposal: Rinse containers well, consider as hazardous waste unless extensively cleaned
Contaminated Packaging: Dispose of as hazardous if residues remain, follow local waste codes
Special Precautions: Avoid contact with other chemicals in disposal streams, segregate from non-hazardous waste
UN Number: 1993
UN Proper Shipping Name: Flammable liquid, n.o.s. (contains propylene glycol t-butyl ether)
Transport Hazard Class: 3 (flammable liquids)
Packing Group: III
Marine Pollutant: Not classified as such
Environmental Hazard: Avoid spillage in cargo holds, restrict movement near water bodies
Transport Label: Flammable Liquid referral triangle required
Special Precaution for user: Secure upright, do not stack excessively, provide fire extinguishers nearby during transfer
OSHA Status: Regulated as hazardous based on flammability and potential health effects
TSCA Inventory: Listed
EU Regulations: Covered by REACH regulation; safety assessment data registered
Canada WHMIS: Classified as B2 - Flammable liquid, D2B - Other toxic effects
Labeling Requirements: GHS pictograms, hazard statements, and precautionary guidance
Other Regulations: Subject to workplace safety rules, hazardous chemical storage and reporting, environmental release notification
SARA 313: Not subject to reporting
California Proposition 65: Not listed as a carcinogen or reproductive toxicant
International Inventories: Listed in Australia, New Zealand, Japan, Philippines, and Korea chemical inventories
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