Material Safety Data Sheet: Propylene Glycol N-Propyl Ether

Identification

Product Name: Propylene Glycol N-Propyl Ether Synonyms: 1-Propoxy-2-Propanol, PGPE Chemical Formula: C6H14O2 CAS Number: 1569-01-3 Use: Solvent in paints, coatings, inks, and cleaning agents Manufacturer: [Insert Manufacturer Details] Contact Information: Emergency number and product information line supplied by the manufacturer Recommended Use Restrictions: Industrial and professional use only, not intended for food, drug, or personal care applications

Hazard Identification

Classification: Flammable liquid (Category 3); Eye irritation (Category 2A); Skin irritation (Category 2) GHS Label Elements: Flame, exclamation mark Signal Word: Warning Hazard Statements: Flammable liquid and vapor; causes skin irritation; causes serious eye irritation Precautionary Statements: Keep away from heat, sparks, open flames. Wear protective gloves, protective clothing, eye protection, and face protection. Use explosion-proof equipment. Wash hands thoroughly after handling.

Composition / Information on Ingredients

Chemical Name: Propylene Glycol N-Propyl Ether Concentration: 99% or higher Impurities: Trace propylene glycol, water (typical manufacturing residues) Other Names: PnP, Glycol Propyl Ether Molecular Weight: 118.17 g/mol

First Aid Measures

Inhalation: Remove victim to fresh air. If not breathing, administer artificial respiration. Seek medical attention for symptoms like coughing or dizziness. Skin Contact: Remove contaminated clothing. Rinse skin with water for at least 15 minutes. Call a doctor if irritation develops. Eye Contact: Flush with water for several minutes, lifting eyelids. Remove contact lenses if present and easy to do. Medical attention advised for persistent pain or redness. Ingestion: Rinse mouth thoroughly. Do not induce vomiting. Drink water to dilute. Get prompt medical help.

Fire-Fighting Measures

Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide, or water spray Specific Hazards: Vapors may form explosive mixture with air. Container may rupture from pressure build-up when involved in a fire. Protective Equipment: Firefighters use self-contained breathing apparatus and full gear. Advice for Firefighters: Cool containers with water spray to prevent explosion. Prevent run-off from entering drains or watercourses.

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate space. Wear appropriate PPE, prevent inhalation and contact. Environmental Precautions: Prevent entry into soil, ditches, sewers, waterways. Notify authorities as required. Methods for Containment: Use inert absorbent materials like sand or earth. Stop leak if safe. Cleanup Procedures: Collect spilled liquid in sealable containers. Wash area with plenty of water. Dispose of in accordance with local regulations.

Handling and Storage

Precautions for Safe Handling: Ground containers when transferring contents. Use in well-ventilated areas. Avoid contact with eyes, skin, clothing. Do not breathe vapors or spray mist. No smoking or open flames nearby. Storage Conditions: Store in original containers tightly closed in a cool, dry, well-ventilated area. Keep away from direct sunlight, heat, spark sources. Incompatible Materials: Strong oxidizers, acids, alkalis. Specific Uses: Only for solvent and industrial cleaning, comply with usage guidelines.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No ACGIH TLV or OSHA PEL established; minimize exposure Engineering Controls: Use mechanical exhaust or general ventilation to keep vapor concentrations low Personal Protective Equipment:

  • Eye Protection: Safety goggles or face shield
  • Hand Protection: Chemical-resistant gloves (nitrile, butyl rubber)
  • Skin Protection: Lab coats, aprons
  • Respiratory Protection: NIOSH-approved respirator if ventilation inadequate
Hygiene Measures: Wash thoroughly after handling. Remove contaminated clothing and wash before reusing.

Physical and Chemical Properties

Appearance: Clear, colorless liquid Odor: Mild, ether-like pH: Not applicable Boiling Point: 146°C Melting Point: -93°C Flash Point: 49°C (closed cup) Vapor Pressure: 3.3 mmHg at 25°C Relative Density: 0.87 g/cm³ Solubility: Miscible with water Viscosity: 2.2 mPa.s at 20°C Partition Coefficient (log Kow): 0.15 Auto-ignition Temperature: 227°C Decomposition Temperature: Not specified Evaporation Rate: 0.3 (butyl acetate=1)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions Hazardous Reactions: May react with strong acids, oxidizers; dangerous gases could evolve Conditions to Avoid: Heat, flame, sparks, incompatible materials Decomposition Products: Carbon monoxide, carbon dioxide, possibly hazardous gases Polymerization: Not expected under normal conditions

Toxicological Information

Likely Routes of Exposure: Inhalation, skin, eye, ingestion Acute Toxicity:

  • Oral LD50 (rat): 3089 mg/kg
  • Dermal LD50 (rabbit): 2380 mg/kg
  • Inhalation LC50 (rat, 6h): Not determined
Symptoms: Eye, skin, and respiratory irritation, headache, nausea Chronic Effects: Prolonged exposure may lead to central nervous system effects, kidney or liver injury Carcinogenicity: No component listed as carcinogen by OSHA, NTP, IARC Mutagenicity/Teratogenicity: No data supporting mutagenic or teratogenic effects at typical exposure

Ecological Information

Ecotoxicity: LC50 (fish, 96 hr): 100 - 200 mg/L Persistence and Degradability: Readily biodegradable Bioaccumulative Potential: Low (log Kow 0.15) Mobility in Soil: High mobility, may leach into groundwater Other Adverse Effects: Large spills may threaten aquatic life due to oxygen depletion

Disposal Considerations

Waste Disposal Methods: Incinerate in approved facility. Do not discharge into sewers or water bodies. Contaminated Packaging: Rinse thoroughly before recycling or disposal. Dispose according to local, state, and federal regulations. Special Precautions: Avoid dispersal of spilled material and runoff.

Transport Information

UN Number: UN 1993 Proper Shipping Name: Flammable Liquid, N.O.S. (Propylene Glycol N-Propyl Ether) Hazard Class: 3 Packing Group: III Marine Pollutant: Not classed as marine pollutant Label Requirements: Flammable liquid Special Transportation Instructions: Secure containers and avoid excessive heat during shipping

Regulatory Information

TSCA Status: Listed REACH Registration: Registered or exempted SARA Title III: Not subject to Section 302, 304, 313 reporting RCRA Status: Not listed as hazardous waste Other Relevant Regulations: Compliant with OSHA Hazard Communication Standard, WHMIS classification: Flammable and toxic California Prop 65: Not listed Labeling: Hazard pictograms and signal word in accordance with GHS requirements Workplace Labeling: Must be labeled with chemical identity and hazard statements for safe handling