Product Name: Propylene Glycol Monomethyl Ether Acetate
Synonyms: 1-Methoxy-2-propanol acetate, PMA, PGMEA
CAS Number: 108-65-6
Recommended Use: Industrial and professional applications, solvent for coatings, inks, cleaners
Supplier Information: Name, address, emergency phone number, and supplier contact details
Emergency Phone Line: 24-hour access for chemical emergencies and information
GHS Classification: Flammable Liquid (Category 3), Eye Irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, causes serious eye irritation, may cause drowsiness or dizziness
Pictograms: Flame, exclamation mark
Precautionary Statements: Keep away from heat, sparks, open flames, or hot surfaces; keep container tightly closed; use explosion-proof equipment; wear protective gloves and eye protection; wash hands thoroughly
Emergency Overview: Clear liquid, mild ether odor, poses inhalation and skin contact risks, may aggravate respiratory and skin conditions
Chemical Name: Propylene Glycol Monomethyl Ether Acetate
CAS Number: 108-65-6
Concentration: Greater than 99% by weight
Impurities: Trace amounts of other glycol ether acetates, non-hazardous stabilizers
Exposure Limits: Occupational exposure limits outlined by regulatory agencies such as OSHA, ACGIH, NIOSH
Inhalation: Move affected person to fresh air, provide oxygen if breathing is difficult, seek medical help if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, seek medical attention if irritation develops
Eye Contact: Rinse with water for at least 15 minutes lifting upper and lower lids, seek medical assistance if irritation continues
Ingestion: Rinse mouth with water, do not induce vomiting, contact poison control or a physician immediately
Most Important Symptoms: Headaches, dizziness, eye redness, possible respiratory irritation
Suitable Extinguishing Media: Alcohol-resistant foam, dry powder, carbon dioxide, water spray
Unsuitable Media: Strong water jets may spread the liquid
Special Hazards: Vapors may form explosive mixtures in air, combustion may produce hazardous gases such as carbon monoxide and carbon dioxide
Protective Equipment for Firefighters: Full protective clothing, self-contained breathing apparatus
Advice for Firefighters: Evacuate area, cool containers with water if exposed to flame, use caution due to risk of container rupture
Decomposition Products: Carbon oxides, potentially other toxic gases
Personal Precautions: Remove ignition sources, ventilate area, avoid breathing vapor, use proper personal protection equipment including gloves and goggles
Environmental Precautions: Do not allow product to enter drains, sewers, or watercourses, contain spill where possible
Method for Cleaning Up: Use non-sparking tools, absorb with inert material such as sand, collect spill for disposal in approved containers, wash spill area with water after removal
Notification Procedures: Report to authorities as required by local regulations
Additional Measures: Restrict access to area until safe
Precautions for Safe Handling: Work in well-ventilated areas, avoid skin and eye contact, prevent build-up of vapors, ground containers to prevent static discharge, keep away from hot surfaces and open flames
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Storage Recommendations: Store in tightly closed original containers in cool, dry, well-ventilated area, keep away from direct sunlight and ignition sources
Specific Storage Hazards: Storage areas require effective ventilation and containment to prevent environmental release, store away from food and beverages
Storage Temperature: Keep below 30°C for stability, avoid freezing temperatures
Engineering Controls: Use mechanical exhaust or local ventilation to keep vapor below regulatory limits
Exposure Limits: OSHA PEL: 50 ppm, ACGIH TLV: 50 ppm, may vary by country and jurisdiction
Personal Protective Equipment: Use chemical-resistant gloves, safety goggles or face shield, impervious clothing as needed
Respiratory Protection: Use an approved respirator when exposure limits are likely to be exceeded or in poorly ventilated spaces
Hygiene Measures: Do not eat, drink, or smoke during use, wash thoroughly after handling, remove contaminated clothing promptly
Appearance: Clear, colorless liquid
Odor: Mild, ether-like
Odor Threshold: Not available
pH: Not applicable (liquid solvent)
Melting Point/Freezing Point: -64°C
Boiling Point: 145°C - 150°C
Flash Point: 45°C (closed cup)
Evaporation Rate: 0.39 (Butyl acetate=1)
Flammability: Flammable liquid
Upper/Lower Flammability Limits: Upper: 8.0%, Lower: 1.5% (volume in air)
Vapor Pressure: 3.7 mmHg at 20°C
Vapor Density: 4.6 (air = 1)
Relative Density: 0.966 at 20°C
Solubility: Miscible with water, alcohols, ethers, hydrocarbons
Partition Coefficient (n-octanol/water): Log Pow = 0.36
Auto-ignition Temperature: 315°C
Decomposition Temperature: Not available
Viscosity: 0.88 mPa.s at 20°C
Molecular Weight: 132.16 g/mol
Stability: Product remains stable under normal conditions and when stored as recommended
Reactivity: Reacts with strong oxidizers, can engage in acid-catalyzed reactions
Hazardous Reactions: Exothermic polymerization unlikely, may react with bases and acids to release heat
Conditions to Avoid: Heat, sparks, open flames, static electricity, incompatible chemicals
Incompatible Materials: Strong oxidizers, acids, alkalis, reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possibly acetic acid and other organic compounds under fire conditions
Acute Toxicity: LD50 (oral, rat) > 5,000 mg/kg, LD50 (dermal, rabbit) > 5,000 mg/kg, LC50 (inhalation, rat, 4h) > 5,300 mg/m³
Skin Corrosion/Irritation: Mild to moderate irritation possible after prolonged contact
Eye Damage/Irritation: Causes eye irritation, redness, tearing
Respiratory Sensitization: May cause mild irritation to respiratory tract at high concentrations
Skin Sensitization: Not expected to sensitize skin
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA
Mutagenicity: No evidence for genetic toxicity
Reproductive Toxicity: Data shows no reproductive or developmental toxicity
Chronic Effects: Prolonged exposure may cause central nervous system effects such as headaches and dizziness
Ecotoxicity: Acute toxicity to fish (96-hr LC50): 161 mg/L (Pimephales promelas), Daphnia magna EC50 (48hr): 408 mg/L
Persistence and Degradability: Readily biodegradable, rapid breakdown in environment
Bioaccumulative Potential: Low, log Pow indicates limited bioaccumulation risk
Mobility in Soil: High, expected to leach into soil and groundwater unless contained
Other Adverse Effects: Harm to aquatic environments at high concentrations, avoid unchecked releases, no known ozone depletion potential
Waste Treatment Methods: Incinerate in approved facility or dispose of in compliance with local regulations
Container Disposal: Triple rinse containers, dispose as hazardous waste
Precautions: Prevent spills, avoid discharge to municipal sewers or waterways
Regulatory Guidance: Follow regional, national, and local environmental regulations for chemical waste disposal
UN Number: UN 3272
Shipping Name: Esters, N.O.S. (Propylene Glycol Monomethyl Ether Acetate)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III (mild hazard)
Environmental Hazards: Not listed as marine pollutant
Special Precautions: Use proper containment, keep vehicle ventilation adequate, avoid sources of ignition, comply with transport regulations for liquids with flash points below 60°C
Transport Labels and Placards: Flammable liquid stickers required during shipping
International Inventories: Listed in TSCA (USA), DSL (Canada), REACH (EU), ENCS (Japan), and other global inventories
SARA Title III: Section 311/312 Hazard Categories: Fire Hazard, Acute Health Hazard
OSHA: Regulated as hazardous substance
EPA: Not identified as persistent, bioaccumulative or toxic chemical
State Regulations: California Proposition 65: Not listed
Workplace Labeling: Must display appropriate hazard symbols and risk phrases
Other Requirements: Follow all applicable local, state, national regulations concerning safe use, handling, disposal, and environmental impact
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