Product Name: Propylene Glycol Monomethacrylate
Synonyms: 2-Hydroxypropyl methacrylate, HPMA
CAS Number: 27813-02-1
Recommended Use: Monomer for polymer production, adhesives, coatings, sealants, dental materials
Manufacturer Contact: Emergency phone number, available technical support line, address of the manufacturing organization, local regulatory offices for immediate guidance
Emergency Overview: Clear, colorless liquid, typically mild odor, used most commonly in industrial environments with standard chemical process controls
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Sensitization (Category 1), Aquatic hazard (Category 3)
Label Elements: Signal Word: Warning, Hazard pictograms: Exclamation mark
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause allergic skin reaction, harmful to aquatic life
Precautionary Statements: Wear protective gloves and clothing, wash thoroughly after handling, avoid release into the environment, use only outdoors or in a well-ventilated area
Routes of Exposure: Skin contact, eye contact, inhalation, ingestion
Chemical Identity: 2-Hydroxypropyl methacrylate
CAS Number: 27813-02-1
Concentration: 95-100%
Impurities: Methacrylic acid (typically below 1%), inhibitors such as MEHQ (4-methoxyphenol) present in low concentrations to prevent polymerization
Other Components: Water (trace), residual solvents as per manufacturing batch
Inhalation: Move person to fresh air, keep them comfortable for breathing, seek medical attention if symptoms such as coughing, dizziness, or headache occur and persist
Skin Contact: Flush area with plenty of water, remove contaminated clothing completely, use mild soap, seek medical assistance for persistent redness or rash
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if present and easy to do, keep eyelids wide apart, seek prompt medical attention for persistent pain or visual disturbance
Ingestion: Rinse mouth with water, never give anything by mouth if unconscious, seek immediate medical advice, keep victim calm
Most Important Symptoms: Redness, pain, burning eyes, sensitization of skin, headache if inhaled for long durations in poorly ventilated places
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, water spray, foam
Unsuitable Extinguishing Media: Direct water jet (can spread liquid)
Specific Hazards: Vapors may form explosive mixtures with air, thermal decomposition can give off toxic fumes including carbon monoxide and other organic compounds
Protective Equipment for Firefighters: Full protective gear including self-contained breathing apparatus, chemical-resistant suit
Advice: Cool nearby containers with water to prevent overheating, evacuate area if large amounts involved, control runoff to prevent entry into water systems
Personal Precautions: Ensure adequate ventilation, wear suitable PPE including chemical-resistant gloves and safety goggles, prevent skin and eye contact
Environmental Precautions: Prevent spillage from entering drains, sewers, or waterways, notify appropriate authorities if significant environmental release occurs
Methods for Cleaning Up: Contain spills with inert, non-combustible absorbent material like sand or vermiculite, collect and dispose in sealed containers, decontaminate area with water and detergent after gross removal
Prevention of Secondary Hazards: Remove all sources of ignition, avoid inhaling vapors especially in confined or unventilated areas
Handling: Work in properly ventilated areas, avoid inhaling vapors or mist, avoid direct contact with skin or eyes, handle in accordance with chemical hygiene protocols, keep away from sources of ignition, ground all equipment, minimize exposure to sunlight or elevated temperature
Storage: Store in cool, dry, well-ventilated space away from heat or direct sunlight, keep containers tightly closed, use UN-approved containers with inhibitor present, segregate from strong oxidizing agents, acids, bases, and free-radical initiators
Technical Measures: Use local exhaust ventilation, keep storage area labelled and access restricted, provide spill containment
Occupational Exposure Limit: No specific OEL established; recommend airborne concentration below 1 mg/m³ to reduce risks
Engineering Controls: Local exhaust ventilation, closed processing systems, eyewash and safety shower stations in case of emergencies
Personal Protective Equipment: Chemical splash goggles, nitrile or butyl rubber gloves, flame-resistant lab coat or coveralls, proper respiratory protection if vapor or aerosol exceeds recommended exposure limits
Hygiene Measures: Avoid eating, drinking or smoking in work area, wash hands and face after handling, remove contaminated clothing immediately
Appearance: Clear, colorless to slightly yellow liquid
Odor: Faint, ester-like
Odor Threshold: Not available
pH: Not determined (neutral)
Melting Point / Freezing Point: -55°C (approximate)
Boiling Point: 80-90°C at reduced pressure (decomposes at higher temperatures)
Flash Point: > 100°C (closed cup)
Evaporation Rate: Not established
Flammability: Forms combustible vapor/air mixtures
Lower / Upper Explosive Limits: 1.6% / 8.9% (estimated)
Vapor Pressure: 0.2 mm Hg at 20°C
Vapor Density: 5.4 (air = 1)
Relative Density: 1.07 g/mL at 20°C
Solubility: Soluble in water, alcohols, and most organic solvents
Partition Coefficient: log Kow ≈ 0.8
Auto-ignition Temperature: Not established
Decomposition Temperature: Not established
Viscosity: 6-10 cP at 20°C
Chemical Stability: Stable under recommended storage conditions with inhibitor present, can polymerize violently if contaminants or heat initiate the reaction
Possibility of Hazardous Reactions: Exothermic polymerization when exposed to heat, light, peroxides, strong acids, or bases
Conditions to Avoid: Direct sunlight, heat sources, uncontrolled temperatures, absence of inhibitor
Incompatible Materials: Strong acids and bases, oxidizing agents, reducing agents, free-radical initiators
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, organic acid vapors
Acute Toxicity: Oral LD50 (rat) 1120-4000 mg/kg, Dermal LD50 (rabbit) >1000 mg/kg, Inhalation toxicity data limited but vapors irritating at high levels
Skin Contact: Irritant, may produce dermatitis with repeated or prolonged contact
Eye Contact: Causes moderate to severe irritation, redness, tearing, blurred vision
Sensitization: Documented cases of allergic reactions in susceptible individuals, especially with repeated exposure
Chronic Effects: Repeated skin exposure may induce sensitization and eczema, unlikely to pose genotoxic or carcinogenic risk based on current animal studies
Other Symptoms: Headache, dizziness, gastrointestinal upset if inhaled or ingested in quantity
Aquatic Toxicity: LC50 (fish, 96 h) 35-100 mg/L, EC50 (daphnia, 48 h) 97 mg/L
Persistence and Degradability: Moderately biodegradable in water and soil, breaks down within weeks under favorable aerobic conditions
Bioaccumulative Potential: Low, based on octanol-water partition coefficient
Mobility in Soil: High, due to water solubility
Other Adverse Effects: Discharge of large volumes or neat material to surface water may cause localized disruption to aquatic ecosystems, impact on wastewater treatment bacteria
Waste Treatment Methods: Collect product in designated sealed hazardous chemical container, incinerate in approved facility under controlled conditions, avoid landfill disposal
Uncontaminated Packaging: Clean thoroughly before recycling, dispose under relevant regulations
Do Not: Discharge to drains or natural water bodies, mix with other incompatible wastes
Local Legislation: Consult national and regional waste management authorities regarding proper classification and handling
UN Number: 2929
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (contains Propylene Glycol Monomethacrylate)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Not classified as a marine pollutant
Transport Labels Required: Toxic substance, keep away from foodstuffs and feed products, avoid heat and sunlight exposure in transit
Special Precautions: Secure container during transport, use spill containment where possible
Regulation: Listed under TSCA (US), EINECS (Europe, 248-666-3), compliant with REACH and Australian AICS
Workplace Exposure Guidance: Follows OSHA Hazard Communication Standard in US, Control of Substances Hazardous to Health (COSHH) in UK
Labeling Requirements: GHS-compliant, includes hazard statements and pictograms, listed for mandatory employee notification
Compliance: Subject to hazardous substance regulations in storage, handling, and transport, proper documentation and training required for legal compliance
User Responsibility: Maintain up-to-date MSDS, regularly review internal safety protocols, ensure waste and emissions controls align with state and national guidelines
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