Product Name: Propylene Glycol Methyl Ether Propionate
Synonyms: PGMEP, 1-Methoxy-2-propanol acetate
CAS Number: 88917-22-0
Recommended Use: Industrial solvent, coatings, paints, inks
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Classification: Flammable liquid (Category 3), Eye irritation (Category 2A), Specific target organ toxicity - single exposure (Category 3)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor; Causes serious eye irritation; May cause drowsiness or dizziness
Pictograms: Flame, Exclamation mark
Precautionary Statements: Keep away from heat, sparks, open flames; No smoking; Use explosion-proof equipment; Wear eye protection; Avoid breathing vapors; If in eyes: Rinse cautiously for several minutes
Chemical: Propylene Glycol Methyl Ether Propionate
CAS Number: 88917-22-0
Concentration: 98% or higher by weight, trace amounts of impurities may include water and probable trace ethers
Inhalation: Remove person to fresh air. Keep at rest in position comfortable for breathing. Seek medical attention if symptoms persist such as headache, dizziness, or respiratory irritation.
Skin contact: Immediately wash with plenty of soap and water. Remove contaminated clothing.
Eye contact: Rinse immediately with plenty of water, lifting eyelids occasionally. Continue flushing for at least 15 minutes. Seek prompt medical advice.
Ingestion: Do not induce vomiting. Rinse mouth with water. Never give anything by mouth to an unconscious person. Obtain medical aid without delay.
Most Important Symptoms: Irritation, central nervous system symptoms like drowsiness, nausea
Notes for the Physician: Symptomatic treatment. Monitor respiratory function.
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide, water spray for cooling containers
Hazards from Combustion: Emits toxic vapors like carbon monoxide and carbon dioxide under fire conditions
Advice for Firefighters: Wear full protective gear and self-contained breathing apparatus. Cool exposed containers with water. Approach fire from upwind.
Special Procedures: Use water spray to keep containers cool. Prevent release to drains or waterways if possible.
Personal Precautions: Avoid breathing vapor. Ensure adequate ventilation. Use personal protective equipment (gloves, goggles, respirator if exposure may exceed limits)
Environmental Precautions: Prevent entry into sewers or waterways. Notify authorities if significant spill contaminates environment.
Methods for Containment: Contain spill with inert material (dry sand, earth). Avoid using sawdust.
Cleanup Methods: Collect spill in suitable containers for disposal. Ventilate area. Wash spill site with water after material pickup.
Handling: Keep container tightly closed. Avoid inhalation of vapor or mist. Use only non-sparking tools. Avoid skin and eye contact. Use in well-ventilated area away from ignition sources.
Storage: Store in a cool, dry, well-ventilated area away from heat, sparks, open flames, oxidizing agents, and acids. Keep container tightly sealed when not in use. Store in original container.
Incompatible Materials: Strong oxidizers, acids, alkalis
Exposure Limits: OSHA PEL (TWA): Not established. ACGIH TLV: 50 ppm (245 mg/m³) as total vapor and aerosol
Engineering Controls: Use local exhaust or general dilution to keep vapor concentrations below limits.
Personal Protection: Wear chemical-resistant gloves (nitrile or neoprene), safety goggles, face shield, protective clothing as appropriate, and, if ventilation inadequate, organic vapor respirator.
Hygiene Measures: Wash thoroughly after handling. Discard contaminated clothing and footwear or clean before reuse.
Appearance: Clear, colorless liquid
Odor: Mild, ether-like
Odor Threshold: Not available
pH: Not applicable
Melting/Freezing Point: -67°C (-88°F)
Boiling Point/Range: 146°C (295°F)
Flash Point: 47°C (117°F), closed cup
Evaporation Rate: 0.2 (Butyl Acetate = 1)
Flammability: Flammable liquid and vapor
Upper/Lower Flammability Limits: 1.1% - 8.7% (v/v)
Vapor Pressure: 0.47 mmHg at 20°C
Vapor Density: 5.1 (Air=1)
Relative Density: 0.96 g/cm³
Solubility: Miscible in water
Partition Coefficient: 0.53 (log Kow)
Auto-ignition Temperature: 345°C (653°F)
Decomposition Temperature: Not readily available
Viscosity: 1.4 cP at 20°C
Reactivity: Stable under recommended storage conditions.
Chemical Stability: Material remains stable under ordinary temperatures and pressures.
Possibility of Hazardous Reactions: May react with strong oxidizing agents.
Conditions to Avoid: Excessive heat, open flame, spark, static discharge
Incompatible Materials: Oxidizers, strong acids, strong bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, and possibly irritating aldehydes and acids
Acute Toxicity: LD50 (oral, rat): 5150 mg/kg; LD50 (dermal, rabbit): >5000 mg/kg
Inhalation: Can cause irritation, headache, drowsiness, dizziness
Skin Contact: Prolonged or repeated exposure may cause mild irritation
Eye Contact: Causes severe irritation and possible corneal injury
Sensitization: No data supporting sensitization in humans or animals
Chronic Effects: Prolonged or repeated exposure may cause symptoms targeting central nervous system
Carcinogenicity: Not classified as carcinogenic by OSHA, IARC, or NTP
Mutagenicity: Not expected to be mutagenic based on available data
Reproductive Toxicity: No evidence of impaired fertility or reproductive toxicity
Ecotoxicity: Not considered highly toxic to aquatic life.
Fish Toxicity: LC50 (Pimephales promelas, 96 h): >100 mg/L
Aquatic Invertebrates: EC50 (Daphnia magna, 48 h): >100 mg/L
Algae: EC50 (algae, 96 hr): >100 mg/L
Persistence and Degradability: Expected to be readily biodegradable.
Bioaccumulation Potential: Low (log Kow <1).
Mobility in Soil: High mobility due to water solubility.
Other Adverse Effects: No known significant environmental effects.
Waste Disposal: Dispose of in accordance with federal, state, and local environmental regulations. Incineration preferred method for large quantities. May be diluted and treated at approved facility.
Container Disposal: Empty container may retain residue. Do not reuse. Triple rinse, puncture, recycle or dispose of through qualified service.
Precautions: Do not allow into drains, surface or ground water. Chemical is classified as hazardous waste (EPA RCRA number may apply depending on concentration and state regulation).
UN Number: UN 3272
Proper Shipping Name: Esters, N.O.S. (Propylene Glycol Methyl Ether Propionate)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Label Required: Flammable Liquid
Environmental Hazards: Not regulated as marine pollutant
Special Precautions for User: Secure containers to prevent spillage or leakage.
Regulatory References: Complies with ICAO/IATA-DGR, IMDG, DOT, ADR provisions
OSHA Status: Classified as hazardous according to OSHA HazCom Standard.
TSCA: Listed.
SARA Title III: Not subject to Section 313 reporting. Not regulated under Section 302 or 304 for extremely hazardous substances.
CERCLA: Does not carry a reportable quantity.
California Proposition 65: Not listed as causing cancer, birth defects, or other reproductive harm.
Canadian WHMIS: B2 (Flammable Liquid), D2B (Other toxic effects - irritant)
EU Classification: F; R10 (Flammable), Xi; R36 (Irritating to eyes); R67 (Vapors may cause drowsiness)
International Inventories: EINECS, DSL, AICS, MITI, KECL, NZIoC all include this substance.
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