Material Safety Data Sheet: Propylene Glycol Dioctanoate

Identification

Product Name: Propylene glycol dioctanoate
Chemical Formula: C19H36O4
Other Names: 1,2-Propanediol dioctanoate; PGDO
CAS Number: 623-82-1
Intended Use: Used as a plasticizer, solvent in cosmetic formulations, lubricants, and specialty industrial fluids
Manufacturer: Contact information for supplier or manufacturer, including emergency number, must appear on the shipping label and be accessible for workplace inquiries.

Hazard Identification

GHS Classification: Not classified as hazardous under GHS criteria
Label Elements: No required hazard pictograms; none assigned signal word
Physical Hazards: Liquid, may create slipping hazards if spilled; not volatile or explosive
Health Hazards: Mild irritation to eyes and skin with prolonged exposure; ingestion can cause gastrointestinal discomfort such as nausea or diarrhea
Environmental Hazards: Low acute aquatic toxicity, but large spills may cause environmental harm and should not enter drains or watercourses
Precautionary Statements: Avoid eye and skin contact; prevent release to the environment

Composition / Information on Ingredients

Chemical Name: Propylene glycol dioctanoate
Synonyms: Propane-1,2-diol dioctanoate
Concentration: ≥98% by weight
Impurities: May contain trace amounts (<2%) of related diesters or monoester impurities
Ingredient Disclosure: No other substances present classified as hazardous according to current regulations

First Aid Measures

Inhalation: Move exposed person to fresh air if respiratory irritation occurs, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin gently with soap and water, seek medical attention if irritation develops
Eye Contact: Rinse eyes cautiously with plenty of water for several minutes, remove contact lenses, call a doctor if irritation continues
Ingestion: Rinse mouth thoroughly, drink water to dilute, do not induce vomiting unless advised by a healthcare professional, get medical attention if you feel unwell
Symptoms: May cause mild skin redness, eye stinging, or stomach upset

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide can extinguish flames involving this substance
Unsuitable Extinguishing Media: Strong water jets may spread spilled material
Fire Hazards: Combustion creates fumes, carbon monoxide and dioxide, possibly irritating vapors
Protective Equipment: Firefighters require protective gear including self-contained breathing apparatus
Hazardous Combustion Products: Burning produces acrid smoke, carbon oxides, other unidentified organic fragments

Accidental Release Measures

Personal Precautions: Wear chemical resistant gloves and safety goggles; avoid inhalation and skin contact
Environmental Precautions: Prevent from entering drains, surface waters, or soil; contain run-off with sand, earth, or non-combustible absorbent.
Cleanup Methods: Soak up spill using absorbent materials such as sand or vermiculite, shovel into secure container for regulated disposal; wash exposed area with water and detergent
Additional Advice: Remove sources of ignition; ventilate the area to disperse vapor

Handling and Storage

Handling: Use in well-ventilated areas, avoid repeated or prolonged contact with skin and eyes; do not eat, drink, or smoke when handling; wash thoroughly after use
Storage: Store tightly closed in cool, dry, and well-ventilated spot, away from direct sunlight, incompatible chemicals, and strong oxidizers
Special Considerations: Keep container upright to prevent leakage; use clean tools and equipment to minimize contamination

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established for this compound
Engineering Controls: Use general or local exhaust ventilation to keep vapor concentrations below nuisance levels
Personal Protective Equipment: Employees wear chemical-resistant gloves (nitrile, neoprene), splash-proof safety goggles, and lab coats or appropriate protective clothing
Respiratory Protection: If exposure to mists or vapors is likely, use NIOSH-approved respirator
Hygiene Measures: Wash hands before breaks and at end of work shift, remove contaminated clothing promptly

Physical and Chemical Properties

State: Clear, oily liquid
Color: Colorless to pale yellow
Odor: Faint, characteristic ester scent
Boiling Point: 313°C (594°F)
Melting Point: -20°C (-4°F)
Density: 0.97 g/cm³ @ 20°C
Solubility: Insoluble in water; mixes with most organic solvents
Vapor Pressure: Negligible at ambient conditions
Flash Point: >160°C (320°F) Closed Cup
Auto-Ignition Temperature: Estimated 370°C (698°F)
Viscosity: 60-80 mPa·s @ 20°C
pH: Not applicable (non-aqueous)
Partition Coefficient (log Kow): Estimated 6.4

Stability and Reactivity

Stability: Chemically stable under ambient storage and use
Incompatibilities: Strong oxidizing agents can cause hazardous reactions
Hazardous Decomposition: On burning, may produce carbon monoxide, carbon dioxide, irritating organic fumes
Polymerization: Not known to undergo hazardous polymerization
Conditions to Avoid: Excessive heating, sources of ignition, strong acids or bases, oxidizing substances

Toxicological Information

Acute Oral Toxicity: LD50 (oral, rat): >5000 mg/kg;
Acute Dermal Toxicity: LD50 (dermal, rabbit): >2000 mg/kg;
Inhalation: Low toxicity by inhalation; vapor is not expected to cause significant harm at room temperature
Skin Corrosion/Irritation: Repeated contact might lead to mild irritation; no evidence of severe harm found in typical workplace exposure
Eye Damage/Irritation: May cause slight and reversible irritation
Respiratory Sensitization: No evidence for respiratory sensitization
Skin Sensitization: Current data finds low risk
Mutagenicity/Carcinogenicity: No studies indicate genetic or cancer risk
Other Effects: Accidental ingestion in large quantities may disturb digestive system

Ecological Information

Ecotoxicity: Acute aquatic toxicity LC50 (fish, 96 h): >100 mg/L
Persistence and Degradability: Biodegradable, breaks down under typical environmental conditions
Bioaccumulative Potential: Potential for accumulation in aquatic organisms; log Kow indicates high partitioning in fat tissues
Mobility in Soil: Low mobility, tends to bind to soils due to low solubility
Other Adverse Effects: Large spills may coat surfaces or disrupt oxygen transfer in water, affecting aquatic life by physical means

Disposal Considerations

Waste Treatment: Dispose through licensed waste disposal operators, using approved methods for organic chemicals
Disposal of Containers: Triple rinse empty containers, then puncture and recycle or dispose per local regulations
Do Not: Release to surface waters, sewers, or natural environments
Relevant Legislation: Observe all local, regional, and national requirements for proper chemical disposal

Transport Information

UN Number: Not regulated as dangerous goods
Proper Shipping Name: Propylene glycol dioctanoate
Transport Hazard Class: Not classified for transport
Packing Group: None assigned
Special Precautions: Transport in covered, leak-proof containers; avoid temperature extremes that may compromise product integrity
Environmental Hazards: Not a marine pollutant by standard definitions

Regulatory Information

Regulatory Listings: Not subject to major international chemical inventories as hazardous (e.g., TSCA, REACH, DSL, AICS)
Labeling Requirements: No specific requirements beyond general chemical safety; provide standard workplace labeling
Health and Safety: Follow chemical hygiene standards as outlined by OSHA, WHMIS, or local laws
Other Applicable Laws: Product may be subject to local agreements covering workplace safety, environmental protection, waste management, and transportation of non-hazardous substances