Material Safety Data Sheet: Propylene Glycol Diacetate

Identification

Product Name: Propylene Glycol Diacetate
Chemical Formula: C7H12O4
CAS Number: 623-84-7
Synonyms: PGDA, 1,2-Propanediol diacetate
Recommended Uses: Solvent in coatings, lacquers, and industrial cleaning
Supplier: Chemical supply companies, industrial distributors
Contact Information: Emergency phone number and company address provided by supplier

Hazard Identification

Classification: Eye irritation, category 2A; skin irritation, category 3
Signal Word: Warning
Hazard Statements: Causes serious eye irritation; may cause mild skin irritation
Pictograms: Exclamation mark symbol
Precautionary Statements: Avoid contact with eyes and skin; wash exposed areas thoroughly after handling; wear protective equipment; seek medical advice if exposure causes symptoms
Other Risks: Vapors may cause drowsiness or dizziness if inhaled in poorly ventilated spaces; not classified as carcinogenic by IARC or OSHA; not listed as a reproductive hazard

Composition / Information on Ingredients

Chemical Name: Propylene Glycol Diacetate
Concentration: >98% by weight
Impurities: Trace amounts of Acetic Acid, Propylene Glycol
Stabilizers/Additives: None indicated in standard supply; consult supplier for specific batch analysis
Substance Type: Single chemical compound

First Aid Measures

Eyes: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing; seek medical attention if irritation persists
Skin: Wash off with soap and water; remove contaminated clothes and wash before reuse; if irritation develops, consult a physician
Inhalation: Move to fresh air; rest in a position comfortable for breathing; if symptoms such as headache or dizziness occur, get medical help
Ingestion: Rinse mouth; do not induce vomiting; seek medical attention if discomfort or adverse effects arise
Notes to Physician: Treat symptomatically; show medical personnel the container or label where possible

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Specific Hazards: Gives off irritating or toxic fumes (carbon oxides) when burned; container may rupture in fire
Protective Equipment: Firefighters should wear self-contained breathing apparatus (SCBA), full protective gear
Special Procedures: Cool fire-exposed containers with water spray to prevent rupture; use water spray or fog to disperse vapors
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, acetic acid fumes

Accidental Release Measures

Personal Protection: Wear safety goggles, chemical resistant gloves, and suitable clothing to avoid contact
Environmental Precautions: Prevent entry into drains, watercourses, and soil; notify relevant authorities in case of significant release
Cleanup Methods: Absorb spill with inert material (sand, diatomaceous earth); collect and place in properly labeled containers; ventilate area; do not flush with water
Decontamination: Wash contaminated surface with soap and water after removal of residue

Handling and Storage

Handling: Use only in well-ventilated areas; avoid breathing vapors; avoid contact with skin and eyes; keep out of reach of children; do not eat, drink, or smoke when handling this material
Storage: Store in tightly closed original container in a cool, dry, well-ventilated place; keep away from sources of ignition, acids, and strong oxidizing agents
Incompatibilities: Avoid contact with oxidizers, strong acids, alkalis
Handling Precautions: Ground and bond containers when transferring to prevent static discharge

Exposure Controls and Personal Protection

Exposure Limits: No OSHA PEL or ACGIH TLV established for propylene glycol diacetate
Engineering Controls: Local exhaust ventilation to control vapor levels; safety shower and eyewash station recommended
Personal Protective Equipment: Chemical-resistant gloves (nitrile, butyl rubber), safety goggles, lab coat or apron, in high vapor situations a NIOSH-approved organic vapor respirator
Hygiene Measures: Wash hands and face after handling; remove contaminated clothing and wash before reuse

Physical and Chemical Properties

Appearance: Clear, colorless to pale yellow liquid
Odor: Slightly sweet, ester-like odor
pH: Not applicable (neat substance)
Melting Point/Freezing Point: Approximately -40°C
Boiling Point: 190–210°C
Flash Point: 93°C (closed cup)
Evaporation Rate: Slower than butyl acetate
Flammability: Combustible liquid
Vapor Pressure: 0.2 mm Hg at 20°C
Vapor Density (air=1): 5
Specific Gravity: 1.08 at 20°C
Solubility: Moderately soluble in water, mixes well with organic solvents
Partition Coefficient (log Kow): Estimated -0.33
Autoignition Temperature: Approximately 415°C
Decomposition Temperature: Not established
Viscosity: Low viscosity liquid

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive under normal use and handling
Hazardous Reactions: Reacts with strong oxidizers releasing heat; may react with strong acids or bases
Decomposition Products: Carbon monoxide, carbon dioxide, acetic acid (on thermal decomposition)
Conditions to Avoid: Excessive heat, open flames, spark sources, incompatible materials

Toxicological Information

Acute Toxicity: Oral LD50 (rat) > 2,000 mg/kg; low acute oral toxicity
Skin Corrosion/Irritation: May cause mild, transient skin irritation
Eye Damage/Irritation: Causes moderate to severe temporary eye irritation
Inhalation: High concentrations of vapor may cause respiratory tract irritation, dizziness, or headaches
Sensitization: No known skin or respiratory sensitization
Chronic Effects: Prolonged or repeated contact may dry or defat skin
Carcinogenicity: Not listed by NTP, IARC, or OSHA as a carcinogen
Mutagenicity/Genotoxicity: Not expected based on available data
Reproductive Toxicity: No evidence in animal studies

Ecological Information

Ecotoxicity: Not classified as hazardous to aquatic life; fish and invertebrate studies show low acute toxicity
Persistence and Degradability: Readily biodegradable in the environment; breakdown by hydrolysis and microbial action
Bioaccumulation: Low potential for bioaccumulation (log Kow below 1)
Mobility in Soil: Highly mobile in soil due to high water solubility
Other Adverse Effects: No known long-term environmental effects from normal uses; large spills may disrupt local wastewater treatment

Disposal Considerations

Waste Handling: Dispose of in accordance with local, regional, national, and international regulations
Waste Treatment Methods: Incinerate under approved, controlled conditions or coordinate with licensed waste disposal contractor
Container Disposal: Rinse empty containers and dispose of as hazardous waste unless thoroughly cleaned
Precautions: Avoid releasing large quantities into environment; comply with all labeling and transport requirements for industrial hazardous waste

Transport Information

UN Number: Not regulated for ground, sea, or air transport (not classified as dangerous goods)
Proper Shipping Name: Propylene Glycol Diacetate
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Labeling Requirements: Standard chemical labeling and hazard communication as per workplace regulations
Special Precautions: Prevent container damage and leaks during transit

Regulatory Information

OSHA Status: Covered under OSHA Hazard Communication Standard for general workplace safety
TSCA: Listed in the US Toxic Substances Control Act inventory
REACH Status (EU): Registered or pre-registered as required
SARA Title III: Not subject to Section 313 reporting
California Proposition 65: Not listed as a chemical known to cause cancer or reproductive harm
Other International Regulations: Complies with regulations in Canada (DSL), Japan, Australia (AICS), and China (IECSC)
Workplace Classification: Employers should include this material in workplace hazard training and emergency action plans