Material Safety Data Sheet – Propanediol Oxybis-

Identification

Product name: Propanediol oxybis-
Synonyms: 2,2'-Oxybispropanol; Dipropylene glycol
Chemical formula: C6H14O3
CAS number: 25265-71-8
Recommended uses: Solvent in cleaning agents, ingredient in personal care products, polymer manufacturing, hydraulic fluids
Supplier contact: Company address and emergency contact phone number must be printed on the packaging and included in company SDS communications
Emergency phone: 24-hour emergency response phone associated with supplier or local poison center

Hazard Identification

Classification: Not classified as hazardous according to GHS criteria for the majority of regulatory regions, though the substance can cause skin and eye irritation in sensitive individuals
Label elements: Not required under GHS, but precautionary statements help guide safety: avoid inhalation, prevent eye and skin contact, wash thoroughly after handling
Physical dangers: May pose slip hazard if spilled on hard surfaces due to viscosity
Health hazards: Overexposure may lead to mild headache, nausea, dizziness, or skin reactions
Environmental hazards: Large releases could contribute to oxygen demand in water systems and cause aquatic issues over time

Composition / Information on Ingredients

Main ingredient: Propanediol oxybis- (purity often exceeds 99%)
Impurities: Trace levels of monopropylene glycol, water, related glycols under 1%
Other ingredients: No hazardous additives present under typical commercial formulations

First Aid Measures

Inhalation: Move exposed person to fresh air, keep comfortable, seek medical advice if symptoms develop
Skin contact: Remove contaminated clothing, wash affected skin with soap and water, seek attention if irritation stays
Eye contact: Flush with water for at least 15 minutes, remove contact lenses if present and easy to do, visit doctor for persistent redness
Ingestion: Rinse mouth, avoid inducing vomiting, drink water to dilute, call a healthcare professional for further assessment

Fire-Fighting Measures

Suitable extinguishing media: Water spray, foam, dry chemical, or carbon dioxide
Unsuitable media: High-pressure water jets may spread spilled material
Specific hazards: Decomposes at elevated temperatures to produce carbon monoxide and carbon dioxide
Protective gear: Firefighters should wear self-contained breathing apparatus and protective clothing
Special procedures: Remove containers from fire area if safe, cool exposed containers with water mist
Combustion products: Release of smoky, acrid fumes if involved in a fire

Accidental Release Measures

Personal precautions: Use protective gloves, safety goggles, avoid inhaling vapors or mists
Environmental precautions: Prevent entry to sewers or waterways by diking spills with absorbent material
Cleanup methods: Stop source, soak up with inert absorbent like sand or earth, shovel into drums for disposal
After spill: Wash area with plenty of water, ventilate area to remove residual vapors, dispose of cleanup waste following official disposal guidance

Handling and Storage

Safe handling: Use with adequate ventilation, do not eat or drink during use, wash thoroughly after handling
Storage conditions: Store in original, tightly closed containers in a cool, dry, well-ventilated place away from strong oxidizers and acids
Incompatibilities: Strong oxidizing agents, strong acids
Storage temperature: Keep below 40°C, protect from moisture to avoid hydrolysis and product degradation
Containers: Use polypropylene, stainless steel, or lined steel drums suited for glycol storage

Exposure Controls and Personal Protection

Exposure limits: No established OSHA or ACGIH exposure limits, but a workplace hygiene standard often applies
Engineering controls: Local exhaust ventilation, mechanical systems to ensure adequate air movement
Personal protection: Impermeable gloves like nitrile or neoprene, safety goggles or glasses, chemical-resistant apron if splash risk present
Respiratory protection: Air-purifying respirators with organic vapor cartridges for high vapor concentrations or accidental large-scale release
Hygiene measures: Wash hands after handling, remove contaminated clothing, avoid inhaling mists or vapors

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid, syrupy consistency
Odor: Mild, barely perceptible
pH: Approximately 7 (neutral) for 50% aqueous solution
Boiling point: Ranges from 230°C to 250°C depending on isomer composition
Melting point: Below -20°C
Flash point: Above 100°C (closed cup, varies with grade)
Solubility: Fully miscible with water, soluble in alcohols
Vapor pressure: Low vapor pressure at room temperature
Density: Roughly 1.02-1.06 g/cm³ at 20°C
Viscosity: High, flows slowly from standard containers

Stability and Reactivity

Chemical stability: Remains stable under normal storage and use temperatures
Reactivity: Reacts with strong oxidizers, acids, can generate heat
Hazardous decomposition products: Carbon monoxide, carbon dioxide, minor formaldehyde at high heat
Conditions to avoid: Prolonged exposure to heat, open flames, contact with incompatible chemicals
Polymerization: No hazardous polymerization anticipated under normal handling

Toxicological Information

Acute toxicity: Oral LD50 for rats around 15,000 mg/kg, low acute toxicity; similar values for dermal exposure
Chronic effects: No long-term adverse effects observed at industrial exposure levels; occasional mild skin sensitization noted
Sensitization: Some reports of irritation or dermatitis after repeated or prolonged contact
Inhalation risk: Low vapor formation at room temperature, but high concentrations can cause headache, dizziness
Carcinogenicity and mutagenicity: Not listed as carcinogen by major health agencies, negative results on key mutagenicity testing
Other effects: No evidence for reproductive toxicity under realistic use conditions

Ecological Information

Ecotoxicity: Not acutely toxic to aquatic organisms at concentrations typically seen in environmental releases; LC50 (fish, 96h) > 10,000 mg/L
Persistence and degradability: Readily biodegradable, rapidly metabolized by environmental bacteria
Bioaccumulation:** Low potential; substance does not concentrate in biological systems
Mobility in soil: Fully miscible with water, will migrate through most soils but tends to degrade quickly by soil microorganisms
Other impacts: Large-scale spills may temporarily deplete oxygen in rivers or streams