Product Name: Propanediol monomethyl ether
Other Names: 1-Methoxy-2-propanol, PGME, Propylene glycol methyl ether
CAS Number: 107-98-2
Recommended Use: Solvent for inks, paints, coatings, cleaning agents
Manufacturer Information: Industrial chemical suppliers and specialty solvent companies
Emergency Phone: Company-provided emergency telephone line
Address: Listed on the supplier's label and Safety Data Sheet
Classification: Flammable liquid (Category 3), Eye irritation (Category 2A), Specific target organ toxicity – single exposure (Category 3, respiratory tract irritation, drowsiness, or dizziness)
Label Elements: Pictogram of flame and exclamation mark, Signal word: Warning
Hazard Statements: Flammable liquid and vapor; Causes serious eye irritation; May cause drowsiness or dizziness
Precautionary Statements: Avoid breathing vapors; Keep away from heat, hot surfaces, sparks, open flames; Use explosion-proof electrical/ventilating/lighting equipment; Wear protective gloves and eye protection
Most Important Hazards: May catch fire easily; Vapors heavier than air; Irritating to eyes and respiratory system; May cause headaches, dizziness, or sleepiness at high concentrations
Chemical Name: Propanediol monomethyl ether
Synonyms: 1-Methoxy-2-propanol, PGME
Concentration: Typically ≥99% (commercial grade)
Chemical Formula: C4H10O2
Impurities/Additives: Minimal, but check supplier MSDS for trace contaminants
Ingredient List: No hazardous components other than main chemical at significant concentrations
Inhalation: Move to fresh air, seek medical attention if symptoms persist such as headache, dizziness, nausea
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water; obtain medical attention for persistent irritation
Eye Contact: Rinse beneath eyelids with water for several minutes, remove contact lenses if present and easy, seek medical advice if redness or pain continues
Ingestion: Do not induce vomiting, rinse mouth thoroughly, drink small amounts of water if conscious, seek immediate medical help
Acute and Delayed Effects: Central nervous system symptoms such as drowsiness, respiratory tract irritation, moderate eye irritation may appear with exposure
Suitable Extinguishing Media: Water fog, dry chemical, alcohol-resistant foam, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet can cause fire to spread
Specific Hazards: Liquid and vapor flammable; may produce toxic gases, carbon monoxide and dioxide under fire
Fire-Fighting Instructions: Wear full protective gear and positive-pressure self-contained breathing apparatus; containers in fire area can explode under heat
Personal Precautions: Evacuate area, keep unauthorized personnel away, cool exposed containers with water spray
Personal Protection: Equip with splash goggles, chemical resistant gloves, impervious clothing, suitable respirator in poor ventilation
Emergency Procedures: Remove ignition sources, ventilate area, prevent further spillage if safe
Environmental Precautions: Avoid discharge into drains, surface waters, soil; report releases to environmental agencies as required by regulation
Cleanup Methods: Contain and collect with inert, non-combustible absorbent (e.g., sand, diatomaceous earth); place in properly labeled containers for disposal; wash area with water after material removal, preventing runoff
Safe Handling: Ground containers, use spark-resistant tools; prevent buildup of electrostatic charges; avoid inhalation or direct skin/eye contact; wash thoroughly after handling
Precautions: No smoking or open flames in use/storage areas; use only in well-ventilated spaces
Safe Storage: Keep containers tightly closed, store in cool, well-ventilated area; keep away from incompatible materials such as strong oxidizers, acids; protect from sunlight and static electricity
Storage Temperature: Store away from direct heat or freezing conditions
Specific Storage Practices: Follow regional storage laws, keep storage areas clearly labeled
Occupational Exposure Limits: ACGIH TLV: 100 ppm TWA; OSHA PEL: 100 ppm TWA (as 1-Methoxy-2-propanol)
Engineering Controls: Ensure adequate local exhaust ventilation; provide eyewash stations and safety showers near handling areas
Respiratory Protection: Use approved masks if exposure limits may be exceeded, especially in confined spaces
Skin Protection: Chemical-resistant gloves such as nitrile or neoprene, long sleeves, and protective shoes
Eye Protection: Safety glasses with side shields or chemical splash goggles; in large volume handling, use full-face shields
Hygiene Measures: Avoid eating, drinking, or smoking during handling; wash hands after use and before breaks or meals
Appearance: Clear, colorless liquid
Odor: Mild, ether-like
pH: Not applicable (neutral compound)
Melting Point: -97°C
Boiling Point: 120°C
Flash Point: 31°C (closed cup)
Evaporation Rate: 0.33 (butyl acetate=1)
Flammability: Flammable
Vapor Pressure: 10 mmHg at 20°C
Vapor Density: 3.1 (air=1)
Specific Gravity: 0.92 at 20°C
Solubility: Miscible with water, many organic solvents
Partition coefficient (n-octanol/water): -0.43
Auto-ignition Temperature: 315°C
Decomposition Temperature: Decomposes above 200°C
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Low, but reacts with strong oxidizers, acids, and bases
Conditions to Avoid: Heat, flames, sparks, sources of static, confined areas without ventilation
Incompatible Materials: Oxidizing agents, strong acids, alkali metals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, potentially toxic fumes during thermal decomposition
Hazardous Polymerization: Will not occur in typical storage conditions
Acute Toxicity: Oral LD50 (rat): ~4,016 mg/kg; Dermal LD50 (rabbit): ~13,000 mg/kg; Inhalation LC50 (rat, 6h): > 6,000 ppm
Potential Health Effects: Inhalation: headache, dizziness, drowsiness, coughing; Skin: mild irritation possible with prolonged exposure; Eyes: moderate irritation, redness; Ingestion: symptoms similar to inhalation, central nervous system depression
Chronic Effects: Prolonged contact may cause skin dryness or cracking; extended vapor exposure may affect nervous system
Carcinogenicity: Not listed as a carcinogen (by NTP, IARC, OSHA)
Mutagenicity: No evidence in standard tests
Reproductive Toxicity: No substantial evidence of risk in studies reviewed by regulatory agencies
Ecotoxicity: Low toxicity to aquatic organisms; LC50 (fish, 96h): ~20,800 mg/L
Persistence and Degradability: Readily biodegradable in the environment, according to OECD tests
Bioaccumulation Potential: Low; log Kow: -0.43, indicates little tendency to accumulate in aquatic organisms
Mobility in Soil: High mobility expected, water-soluble substance
Other Adverse Effects: If large volumes enter watercourses, may reduce dissolved oxygen and affect aquatic life
Additional Info: Avoid spills into environment; many regions regulate quantities released into surface water or drains
Waste Treatment Methods: Collect in suitable container, send to licensed chemical waste incinerator or hazardous waste facility
Product Disposal: Handle as hazardous waste, following regional or national guidelines
Container Disposal: Containers must be drained, triple rinsed, punctured, and recycled if possible, otherwise dispose as hazardous waste
Precautions: Do not pour into sewers, ground, or water bodies; avoid landfill unless specifically permitted for hazardous chemical waste
Regulatory Waste Codes: Dispose of according to relevant EPA and local hazardous waste codes for solvent chemicals
UN Number: 3092
Proper Shipping Name: 1-Methoxy-2-propanol
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Label Required: Flammable liquid
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Transport in upright, sealed containers; avoid rough handling; follow all local, national, and international transportation regulations
Additional Info: Review bill of lading, ensure correct placarding for shipments by road, rail, air, or sea
US Regulations: Listed on TSCA Inventory; SARA Title III Sec. 313 reporting not required in routine use levels
European Regulations: Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) compliant; classified for supply under CLP Regulation
Canada: DSL listed, subject to WHMIS; Controlled Product, Class B2 (flammable liquid), Class D2B (eye irritant)
Australia: Listed on AICS
Other Regional Regulations: Subject to GHS (Globally Harmonized System) labeling and classification requirements worldwide
Specific National Requirements: Review occupational exposure limits and environmental registration depending on jurisdiction
Other Legal Requirements: Safety data sheets must be provided to users, training recommended for handlers
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