Product Name: Poly(propylene glycol) 4000
Synonyms: Polyoxypropylene glycol, PPG-4000
Chemical Formula: C3H8O2)_n, where n represents degree of polymerization for an average molecular weight of 4000
CAS Number: 25322-69-4
Manufacturer: Supplier details available upon request from local distributor
Recommended Use: Used primarily as a base polymer for adhesives, coatings, sealants, chemical intermediates, and lubricants
Emergency Contact: Chemtrec: +1-800-424-9300 (U.S.), local emergency numbers available internationally
GHS Classification: Not classified as hazardous per GHS criteria
Signal Word: None required
Hazard Statements: May cause mild skin and eye irritation, not readily absorbed through intact skin
Precautionary Statements: Avoid prolonged or repeated skin contact, avoid inhalation of mist, wash hands thoroughly after handling
Routes of Exposure: Skin, eyes, inhalation of mist or dust
Symptoms: Mild eye or skin irritation, possible slight respiratory discomfort at high concentrations
Potential Chronic Effects: Limited evidence for chronic toxicity in animal studies, not mutagenic or carcinogenic
Substance: Poly(propylene glycol) 4000
Concentration: 98% or greater, substance in pure form
Impurities: Trace residual monomers (propylene oxide & diols, less than 1%)
Chemical Family: Polyether glycol
Hazardous Components: None expected in typical batches
Eye Contact: Rinse with running water for 10-15 minutes, remove contact lenses if present, seek medical attention if irritation persists
Skin Contact: Wash with soap and water, remove contaminated clothing, consult a doctor if irritation develops
Inhalation: Move to fresh air, seek medical attention if symptoms develop
Ingestion: Rinse mouth with water, do not induce vomiting, contact healthcare professional if large quantity ingested
Advice to Physician: Treat symptomatically, no specific antidote known
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Media: Direct high-pressure water jet could spread product
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, low molecular weight hydrocarbons, possible formaldehyde
Special Protective Equipment: Use self-contained breathing apparatus and full protective gear
Fire and Explosion Hazards: Product is not easily combustible, can burn and produce toxic smoke at high temperatures
Flash Point: Exceeds 200°C (closed cup), high thermal stability
Personal Precautions: Wear appropriate PPE including gloves, safety glasses, and impervious clothing, ensure adequate ventilation
Environmental Protection: Prevent entry into drains, sewers, waterways, and soil
Cleanup Methods: Absorb spill with inert material like sand or vermiculite, collect in marked containers for safe disposal
Spill Size Considerations: For large spills, dike area and pump out, for small spills, wipe up with absorbent
Decontamination: Wash affected area with soap and water, ventilate area
Handling Precautions: Avoid direct contact with eyes, skin, and clothing, use in well-ventilated area, keep containers closed when not in use
Safe Storage Conditions: Store in original tightly sealed containers, keep in cool, dry, and well-ventilated place away from heat sources, protect from sunlight and frost
Incompatibles: Strong oxidizing agents, strong acids or bases
Specific Use Recommendations: Use only as intended, don’t reuse empty containers for food or drink
Bulk Storage Notes: Tanks should have secondary containment to prevent environmental release
Occupational Exposure Limits: No established limits (OSHA, ACGIH)
Engineering Controls: Good general ventilation sufficient, local exhaust for mist or aerosol generation
Eye Protection: Safety goggles or face shield recommended for splash risk
Skin Protection: Chemical-resistant gloves (nitrile, neoprene), long sleeves, and protective footwear
Respiratory Protection: Not necessary under normal use, NIOSH-certified mask if mist or aerosol present
Hygiene Measures: Wash hands after handling, avoid eating or drinking while working
Appearance: Clear, colorless to pale yellow, viscous liquid
Odor: Mild, faint ether-like
Molecular Weight: Approximately 4000 g/mol
Boiling Point: Above 250°C (482°F)
Melting Point: Approximately 40-45°C (104-113°F)
Vapor Pressure: Negligible at ambient temperature
Solubility in Water: Slightly soluble, forms emulsions with vigorous mixing
Density: 1.010 to 1.030 g/cm³ (20°C)
Viscosity: High, thixotropic
pH: Neutral (approximately 5.5-7.0 in 10% solution)
Chemical Stability: Stable under recommended usage and storage conditions
Conditions to Avoid: Prolonged heating above 200°C, open flames, strong sunlight, and freezing temperatures
Materials to Avoid: Strong acids, strong bases, oxidizers
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possible formaldehyde at high temperatures
Polymerization: Not expected to occur under normal storage or use
Acute Toxicity: Low toxicity by oral, dermal, and inhalation exposure; LD50 (oral, rat) > 5000 mg/kg
Skin Corrosion/Irritation: May cause mild irritation with prolonged or repeated exposure
Eye Damage/Irritation: May cause slight, reversible irritation
Sensitization: Not a known sensitizer
Mutagenicity & Carcinogenicity: Based on available studies, does not cause genetic mutations or cancer
Long-Term Effects: No evidence of organ-specific toxicity, minimal risk of adverse health effects under normal handling
Ecotoxicity: Not expected to be harmful to aquatic life, acute toxicity to fish (LC50, 96 hr, rainbow trout) > 1000 mg/L
Persistence and Degradability: Moderately biodegradable in natural environments, undergoes slow microbial breakdown
Bioaccumulative Potential: Low, does not readily accumulate in organisms
Mobility in Soil: Slight water solubility suggests limited mobility, product tends to remain in soil matrices
Other Adverse Effects: No evidence for ozone depletion or endocrine disruption
Waste Handling: Dispose in accordance with federal, state, and local regulations, do not pour into drains, water bodies, or soil
Contaminated Packaging: Empty containers should be triple-rinsed and offered for recycling or disposal as hazardous waste if contaminated
Industrial Disposal Methods: Incineration or landfill at approved facilities
Other Recommendations: Avoid creating mist or aerosol during disposal, document waste type for traceability
UN Number: Not regulated for transport under UN, IATA, IMDG codes
Proper Shipping Name: Not classified as dangerous goods
Transport Hazards Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant
Special Precautions: Keep containers sealed during transport, avoid rough handling that could cause leaks
Bulk Transport: Check compatibility with tank coatings and lines before bulk shipment
Safety, Health and Environmental Regulations: Listed on major chemical inventories (TSCA, EINECS/ELINCS, DSL, AICS)
SARA Title III: Not a SARA 302, 304, or 313 listed chemical
CERCLA: Not a hazardous substance
California Prop 65: Not listed
REACH Status: Exempt as a polymer, monomer registration available
Other National Regulations: Workers should receive training on chemical handling procedures as per OSHA's Hazard Communication Standard
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