Product Name: Norepinephrine bitartrate
Chemical Name: norepinephrine bitartrate
Synonyms: levo-noradrenaline bitartrate, noradrenaline bitartrate
CAS Number: 108341-18-0
Recommended Use: pharmaceutical intermediate, research and laboratory reagent
Supplier Contact: Emergency contact information found on shipping label or supplier SDS
Molecular Formula: C8H11NO3•C4H6O6
EC Number: 200-241-0
Classification: Acute toxicity (oral, dermal, inhalation), Eye irritation, Skin irritation
Hazard Statements: Harmful if swallowed, causes eye and skin irritation
Signal Word: Warning
Precautionary Statements: Avoid contact with skin and eyes, do not breathe dust, wash hands thoroughly after handling, wear suitable protective equipment
Potential Health Effects: May cause symptoms related to cardiovascular and nervous systems on exposure
Label Elements: Exclamation mark symbol
Chemical Identity: Norepinephrine bitartrate
Concentration: 100%
CAS Number: 108341-18-0
Impurities: No significant hazardous impurities above regulatory disclosure cutoffs
Ingredient Description: White to off-white crystalline powder
Inhalation: Remove victim to fresh air, get medical attention if symptoms persist, keep patient at rest
Skin Contact: Wash off thoroughly with soap and water, remove contaminated clothing, see a doctor for lasting irritation
Eye Contact: Rinse with plenty of water for several minutes, lift eyelids to ensure removal, seek medical attention
Ingestion: Rinse mouth with water, do not induce vomiting unless advised by medical professionals, seek immediate medical help
Notes to Physician: Treat symptomatically, monitor vital functions, provide supportive treatment as needed
Suitable Extinguishing Media: Dry chemical, carbon dioxide (CO2), or foam
Extinguishing Media Not to Use: Direct water jet for large fires
Specific Hazards: Emits toxic fumes of nitrogen oxides and carbon oxides during combustion
Protective Equipment: Full protective clothing and self-contained breathing apparatus for all fire situations
Special Procedures: Approach from upwind, prevent run-off into drains and water sources
Personal Precautions: Wear chemical resistant gloves, safety goggles, and protective clothing
Environmental Precautions: Prevent entry into drains, sewers, or surface water
Containment: Sweep up carefully to avoid dusting, transfer to suitable containers for disposal, use tools that minimize dust formation
Cleanup Methods: Ventilate area, wash spill site after material pickup is complete, discard cleaning materials as hazardous waste
Handling: Use in well-ventilated areas, avoid skin or eye contact, wash hands after use, handle powder in fume hood if possible
Storage Conditions: Keep container tightly closed and in a cool, dry place, no exposure to direct sunlight or heat sources
Incompatibilities: Strong oxidizing agents, acids, and alkalis
Packing Materials: Store in original containers or chemically compatible labeled containers
Engineering Controls: Use mechanical exhaust or laboratory fume hood, provide eye wash and safety showers in work area
Personal Protective Equipment: Protective gloves (nitrile recommended), safety goggles, laboratory coat
Respiratory Protection: Suitable respirator if dust formation is likely
Hygiene Measures: No eating, drinking, or smoking during handling, wash thoroughly after handling, remove contaminated clothing
Exposure Limits: No specific occupational exposure limits have been established
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not determined
pH: 3.3 – 4.5 (5% solution)
Melting Point/Freezing Point: Decomposes above 150°C
Boiling Point: Not determined
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not flammable
Vapor Pressure: Not available
Vapor Density: Not available
Relative Density: Not determined
Solubility in Water: Freely soluble
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Above 150°C
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions
Reactivity: No dangerous reactions known under normal use
Conditions to Avoid: Exposure to light, heat, and moisture can cause degradation
Materials to Avoid: Strong oxidizing agents, acids, alkalis
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides
Likely Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Harmful if swallowed; LD50 oral in rats: 105 mg/kg
Skin Corrosion/Irritation: Causes mild skin irritation
Eye Damage/Irritation: May cause irritation
Respiratory Sensitization: Dust may irritate airways
Chronic Effects: Repeated or prolonged exposure may affect cardiovascular and nervous system
Other Toxicological Data: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity in available literature
Ecotoxicity: May be harmful to aquatic life in high concentrations
Persistence and Degradability: No data available; likely degrades biologically over time
Bioaccumulative Potential: No data suggests significant bioaccumulation
Mobility in Soil: No specific data, likely moderate mobility due to solubility
Other Adverse Effects: Avoid release to the environment
Disposal Methods: Dispose of according to local, regional, and national regulations for hazardous waste
Contaminated Packaging: Dispose of containers as hazardous waste, ensure complete cleaning prior to recycling or disposal
Additional Disposal Considerations: Do not allow into sewers, drains, or any water courses, consult licensed waste disposal contractor
UN Number: Not regulated for transport
Transport Hazard Class: Not classified as a dangerous good
Packing Group: Not applicable
Proper Shipping Name: Norepinephrine bitartrate
Environmental Hazards: Not considered a marine pollutant
Special Precautions: Secure packaging to prevent spill, avoid extreme temperatures during transport
US TSCA: Not listed due to pharmaceutical application
OSHA Regulation: Not specifically listed
SARA Title III: Not subject to reporting requirements
EU Regulations: Not classified as hazardous under current CLP regulation
Canada WHMIS: Not specifically listed
Other Regulations: Use requires trained personnel, observe chemical hygiene and laboratory safety practices
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