Product Name: Noradrenaline hydrogen tartrate
Chemical Formula: C8H11NO3 · C4H6O6
Synonyms: Norepinephrine bitartrate, Noradrenaline bitartrate
CAS Number: 62-31-7
Intended Use: Research and laboratory use, prescription pharmaceutical ingredient
Manufacturer: Contact supplier for details
Emergency Contact: Refer to local emergency response services or regional poison control
Recommended Restrictions: Medical professionals only, not for general public use
GHS Classification: Acute toxicity (oral, dermal, inhalation), Eye irritation, Skin sensitization
Hazard Statements: May cause serious eye and skin irritation, harmful if swallowed, inhaled, or absorbed through skin, can lead to respiratory issues on overexposure, triggers allergic skin reactions in sensitive individuals
Pictogram: Exclamation mark (irritant); Health hazard
Signal Word: Warning
Precautionary Statements: Avoid all contact with eyes, skin, and clothing, do not breathe dust or fumes, wash thoroughly after handling and before eating, do not eat, drink, or smoke during work, secure proper ventilation at work site
Symptoms of Exposure: Headache, shortness of breath, skin/redness, eye pain, cardiovascular irregularities, tremors, nausea, and possible loss of consciousness after large exposure
Component: Noradrenaline hydrogen tartrate
Chemical Name: 4-(2-amino-1-hydroxyethyl)-1,2-benzenediol hydrogen tartrate
Concentration: Typically >98% pure (USP, EP, or equivalent standard)
Impurities: Trace amounts of residual solvents, heavy metals below regulated thresholds
Other Components: No significant non-active ingredients in bulk material intended for compounding or formulation
Inhalation: Remove person from area to fresh air at once, keep at rest, monitor for breathing difficulty; give artificial respiration if breathing stops, seek immediate medical attention
Skin Contact: Remove contaminated clothing, rinse affected area thoroughly with soap and water for at least fifteen minutes; consult physician in case of irritation or persistent discomfort
Eye Contact: Rinse eyes gently with water for at least fifteen minutes, lifting eyelids occasionally; medical attention needed to prevent potential eye damage
Ingestion: Rinse mouth with water, never induce vomiting, keep patient calm, contact physician or poison center urgently
Protective Advice for Rescuers: Use gloves and splash goggles, avoid unnecessary exposure, wash hands thoroughly after intervention
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, or foam, choose based on surrounding fire
Unsuitable Extinguishing Media: Direct water jet can spread chemical
Hazards from Combustion: May emit toxic fumes such as carbon oxides, nitrogen oxides, other unidentified organic compounds on combustion or thermal breakdown
Special Protective Actions for Firefighters: Use self-contained breathing apparatus, wear full-body protection, avoid inhaling combustion gases
Additional Fire Information: Cool containers with water spray to prevent pressure build-up, limit spread of chemical residue runoff
Personal Precautions: Evacuate non-essential personnel, avoid direct contact with spilled material, wear suitable PPE (N95 respirator, gloves, goggles, lab coat)
Environmental Precautions: Prevent entry into drains, sewage, water courses, and soil, use containment to control spillage
Clean-up Methods: Scoop, sweep, or vacuum up dry material into suitable container for disposal, use wet cloth or absorbent pads for residual dust, ventilate area after cleanup
Disposal of Clean-up Materials: Place waste in clearly labeled hazardous waste containers, follow legal regulations for chemical disposal
Safe Handling: Wear appropriate personal protective equipment, avoid generation of airborne dust, handle in fume hood if available, minimize exposure through dermal or inhalation routes, avoid eating and drinking in work area
Storage Conditions: Store in sealed, light-resistant containers, avoid moisture and heat, keep separate from food, animal feed, and incompatible chemicals (strong oxidizers, acids)
Temperature Requirements: Maintain temperature between 2°C-8°C (refrigerated), short excursions permitted up to 25°C
Storage Area Requirements: Secure access, ventilation, appropriate chemical signage, away from ignition sources
Incompatibilities: Strong oxidants, strong acids, bases
Exposure Limit Values: No established occupational exposure limits; minimize exposure by all routes
Engineering Controls: Operate with mechanical ventilation or fume extraction, work in fume hood during weighing and manipulation
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, laboratory coat, closed-toe shoes, respiratory protection where dust or aerosols are present
Hygiene Measures: Wash hands, face, and exposed skin after handling, do not bring contaminated PPE home, launder work clothing frequently
Occupational Sensing: Monitor area for dust or vapors if large quantities handled
Physical State: Solid, crystalline powder
Color: White to slightly off-white
Odor: Odorless or faintly characteristic
Molecular Weight: 337.3 g/mol
pH (1% solution): 3.0-4.5
Melting Point: Decomposes at about 174°C
Solubility: Highly soluble in water, sparingly soluble in ethanol
Other Information: Stable under recommended storage conditions, deliquescent in high humidity
Chemical Stability: Stable under normal refrigerated storage, deteriorates in light or heat, sensitive to moisture
Reactive Conditions: Avoid strong oxidizing agents, reducing agents, acids, bases, elevated temperatures, light
Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, tarry residues
Hazardous Reactions: No unexpected hazardous reactivity expected under recommended handling
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Noradrenaline can cause serious cardiovascular disturbances (hypertension, rapid heart rate, arrhythmia), CNS stimulation, tremors, anxiety, severe headache, in high doses may result in cardiac arrest or convulsions
Chronic Toxicity: Long-term or repeated exposure can affect cardiovascular, nervous, and endocrine systems
Carcinogenicity: No information indicating carcinogenic risk in humans
Reproductive and Developmental Effects: Animal studies suggest possible fetal effects at high doses, insufficient human data
Sensitization: Can provoke allergic reactions and skin sensitization in predisposed individuals
Ecotoxicity: Toxic to aquatic organisms in high concentrations, may cause long-term effects in aquatic environments
Persistence and Degradability: Biodegradable to some extent but degradation depends on environmental conditions; may persist in sediments
Bioaccumulative Potential: Low to moderate bioaccumulation expected
Mobility in Soil: Mobile in aqueous solutions, potential for contamination if released
Other Adverse Effects: Precaution advised to avoid environmental release
Waste Handling: Manage as hazardous chemical waste per local, regional, and national guidelines
Container Disposal: Triple rinse and then puncture containers before discarding, observe all label precautions when disposing
Methods of Disposal: Incineration by authorized chemical waste facility, do not dispose with regular household or laboratory trash
Environmental Precautions: Prevent leaks into water or soil during disposal, do not flush into surface waters or drains
UN Number: 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (noradrenaline hydrogen tartrate)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Special Precautions: Protect against rough handling, avoid contamination of cargo holds, keep containers tightly closed and away from incompatible materials
Labeling Requirements: Toxic substance mark, hazard pictograms per relevant regulations (ADR/RID, IMDG, IATA)
Classification: Regulated as hazardous pharmaceutical and laboratory chemical
Hazard Symbols: GHS07 (exclamation mark), GHS06 (skull and crossbones); compliance with local workplace safety laws
Inventory Status: Listed in inventories including TSCA (US), EINECS (EU), DSL (Canada), AICS (Australia)
Labeling Provisions: GHS-compliant, per OSHA Hazard Communication Standard and CLP Regulation (EC)
Additional Legal Requirements: Subject to transport, environment, and health regulations concerning toxic, medicament, and controlled substances; always consult national laws and institutional policies before use or disposal
Providing high-quality chemical products and logistics solutions for global trade partners.
