MSDS for N N-DIMETHYL-3-AMINO-1,2-PROPANEDIOL

Identification

Product Name: N N-Dimethyl-3-amino-1,2-propanediol
Chemical Formula: C5H13NO2
Synonyms: 3-Amino-1,2-propanediol, N,N-dimethyl-; Dimethylamino-propanediol
Recommended Use: Used as a chemical intermediate in organic synthesis and potential pharmaceutical manufacturing
Supplier: Chemical manufacturer or distributor information posted on packaging or invoice
Contact Information: Emergency telephone numbers and address should be included from the supplier for fast response to exposures, spills, or fires
CAS Number: 67345-94-2
UN Number: Not classified as dangerous for transport by most regulations; check local guidelines

Hazard Identification

GHS Classification: Irritant for skin and eyes; possible harmful by inhalation or swallowing
Pictograms: Exclamation mark for acute toxicity and skin/eye irritation
Signal Word: Warning
Hazard Statements: Causes skin irritation; causes serious eye irritation; may be harmful if swallowed or inhaled
Precautionary Statements: Wear protective gloves, clothing, eye, and face protection; wash exposed skin thoroughly after handling; avoid breathing dust, vapors, or mist; use only outdoors or in a well-ventilated area

Composition / Information on Ingredients

Chemical Identity: N N-Dimethyl-3-amino-1,2-propanediol
Concentration: Typically above 98% as supplied
Impurities: Water and trace levels of other amines or diols (usually less than 2%)
Additives: None present except for stabilizers if specified by the supplier

First Aid Measures

Inhalation: Move to fresh air promptly; if symptoms such as cough, headache, or shortness of breath develop, seek medical attention
Skin Contact: Remove contaminated clothing; wash skin thoroughly with water and soap; keep rinsing for at least 15 minutes if irritation occurs
Eye Contact: Immediately flush eyes with plenty of water, pulling eyelids apart; rinse for several minutes; contact a physician for persistent irritation
Ingestion: Rinse mouth with water; do not induce vomiting; offer water if conscious; get medical help right away
Note to Physicians: Symptoms can be delayed; treat symptomatically; monitor for respiratory issues and skin or eye damage

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or foam
Specific Hazards: May give off carbon oxides and nitrogen oxides if burned; vapors may form explosive mixtures with air at high temperatures
Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing to avoid contact with vapors and decomposition products
Special Procedures: Cool containers exposed to fire with water spray; avoid releasing runoff from fire control to sewers or waterways

Accidental Release Measures

Personal Protection: Wear chemical-resistant gloves, goggles, clothing, and if possible, a face shield
Environmental Protection: Avoid letting substance enter soil, surface water, or drains; contain spill as quickly as possible
Clean-Up Methods: Absorb spill with inert material such as sand or vermiculite; place residues in sealed containers for proper disposal; ventilate area and wash site with water after material pick-up

Handling and Storage

Precautions: Handle in well-ventilated area; minimize contact with skin and eyes; use proper grounding and bonding when transferring materials; never use near open flames or heat sources
Storage: Keep in tightly closed containers; store in a cool, dry, and well-ventilated space, away from incompatible materials such as oxidizers, acids, and bases; label containers clearly

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation; prevent vapor buildup in work areas
Personal Protection Equipment: Resistant gloves (nitrile or neoprene), safety goggles, face shield if splash risk, long-sleeved lab coats
Respiratory Protection: Use NIOSH/MSHA approved respirators if vapor/mist concentrations exceed occupational exposure limits
Hygiene Measures: Wash hands before eating, drinking, or smoking; shower and change clothes after handling

Physical and Chemical Properties

Appearance: Clear, colorless to pale yellow liquid or crystalline solid
Odor: Ammonia- or amine-like odor
Molecular Weight: 119.2 g/mol
Boiling Point: 230-250°C under atmospheric pressure
Melting Point: Data not widely published; likely below room temperature
Solubility: Easily dissolves in water; also soluble in ethanol
Density: Around 1.05 g/cm³ at 25°C
Vapor Pressure: Low, less than 1 mmHg at 20°C
pH (1% solution): Slightly basic, between 9 and 10

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures
Reactivity: Reacts with strong acids, strong bases, oxidizing agents; can form dangerous gases if heated to decomposition
Hazardous Decomposition Products: Emits nitrogen oxides, carbon monoxide, carbon dioxide under fire conditions
Polymerization: Not known to occur under recommended conditions

Toxicological Information

Acute Toxicity: Data limited; estimated oral LD50 (rat) above 500 mg/kg; inhalation and dermal routes less documented
Skin Contact: Causes irritation, redness, and potential dermatitis with prolonged or repeated exposure
Eye Contact: Causes burning, watering, and redness; may cause corneal damage in severe cases
Chronic Effects: Repeated exposure can lead to sensitization reactions or systemic toxicity affecting liver and kidney
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a known carcinogen
Other Effects: Central nervous system depression at high concentrations

Ecological Information

Aquatic Toxicity: Expected to be toxic to fish and aquatic organisms at high concentrations
Persistence and Degradability: Can biodegrade under aerobic conditions, but stable enough to persist temporarily
Bioaccumulation: Not expected to significantly bioaccumulate based on molecular size and water solubility
Mobility in Soil: Moves rapidly through soil due to high solubility in water
Other Risks: May disrupt biological treatment systems if released in significant amounts

Disposal Considerations

Waste Disposal: Collect waste in clearly labeled containers; do not release directly to sewer or the environment
Disposal Methods: Incinerate in an approved facility or dispose of at licensed hazardous waste site, following all government regulations
Containers: Rinse empty containers with plenty of water before disposal, or triple rinse and puncture to prevent reuse

Transport Information

UN Number: Not regulated for most modes of transport;
Proper Shipping Name: Not classified as a dangerous good; check specific regulations when shipping internationally
Hazard Class: None assigned
Packing Group: None assigned
Special Precautions: Secure packaging to prevent leaks or spills; avoid loading near food or incompatible chemicals

Regulatory Information

TSCA Status: Listed on the Toxic Substances Control Act Inventory in the United States
DSL/NDSL: Verified against Canadian registry— confirm listing before import/export
EINECS/ELINCS: European inventory checked; usually listed under EC Number 267-700-7
Other Regulations: Comply with workplace exposure laws; label in accordance with GHS and local requirements; employer must provide workers with safety information and training related to chemical hazards