Material Safety Data Sheet for Monopropylene Glycol

Identification

Product Name: Monopropylene Glycol
Synonyms: 1,2-Propanediol, Propylene Glycol
Chemical Formula: C3H8O2
CAS Number: 57-55-6
Manufacturer: Typically provided by supplier upon purchase; consult label or purchasing records.
Intended Uses: Ingredient in foods, cosmetics, pharmaceuticals, antifreeze, and industrial applications.
Supplier Contact: Reference to on-site emergency numbers, supplier emergency hotline available on product label.

Hazard Identification

GHS Classification: Substance is not classified as hazardous according to GHS standards.
Label Elements: No pictogram required, signal word not mandated, hazard statements not applicable, precautionary statements oriented towards safe handling.
Potential Health Effects: Mild central nervous system effects may occur after ingestion of large quantities; skin contact does not cause significant irritation for most people; eye exposure can cause mild, temporary discomfort.
Physical Dangers: Product does not ignite easily, vapors at high temperatures could contribute to a minor fire risk.
Environmental Risks: Not expected to cause short-term or long-term harmful effects to aquatic organisms at normal environmental concentrations.

Composition / Information on Ingredients

Chemical Name: Monopropylene Glycol
Content: 99-100% (by volume)
Chemical Formula: C3H8O2
EC Number: 200-338-0
Impurities/Additives: Trace amounts of water or proprietary stabilizers may be present given the grade and source of supply.

First Aid Measures

Inhalation: Remove person to fresh air, monitor for symptoms such as drowsiness or headache, offer water. Seek medical attention if discomfort persists.
Skin Contact: Rinse exposed area with water, remove contaminated clothing, wash with soap if necessary.
Eye Contact: Rinse immediately with plenty of water for several minutes, avoid rubbing, seek further help if discomfort continues.
Ingestion: Rinse mouth, offer water to drink, do not induce vomiting unless directed by medical personnel, consult doctor if large volume was consumed or symptoms develop.

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide.
Special Hazards: Vapors may accumulate in poorly-ventilated spaces under fire conditions, forming mild explosion risk.
Protective Equipment: Fire fighters should wear self-contained breathing apparatus and protective clothing.
Combustion Products: Carbon monoxide, carbon dioxide, and possibly aldehydes if combustion is incomplete.

Accidental Release Measures

Personal Precautions: Wear appropriate gloves and eye protection, ventilate area.
Environmental Precautions: Retain contaminated water, prevent discharge to waterways.
Cleanup Methods: Absorb with sand, soil, or inert material, sweep or shovel into containers, wash spill site after material pickup is complete.
Notification Procedures: Follow local regulations for spill response and waste disposal reporting.

Handling and Storage

Handling: Avoid contact with eyes, minimize prolonged skin contact, keep container closed when not in use, ensure good ventilation in work area, avoid breathing mists.
Storage: Store in cool, dry, and well-ventilated area, away from strong oxidizers and acids, keep in tightly sealed containers, protect from direct sunlight and sources of heat.
Special Measures: Use antistatic containers if possible for large-scale handling.

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established in most regions, consult local authority.
Engineering Controls: Use local exhaust ventilation for confined spaces, provide eyewash stations near work area.
Personal Protective Equipment: Gloves made of nitrile, PVC or similar, safety goggles, protective clothing upon risk assessment.
Respiratory Protection: Not usually needed under normal conditions; for mists or heating, use appropriate respirator.

Physical and Chemical Properties

Appearance: Clear, colorless, and viscous liquid
Odor: Nearly odorless, faint sweet taste
Melting Point: -59°C
Boiling Point: 188.2°C
Flash Point: Approximately 104°C (closed cup)
Density: 1.036 g/cm³ at 20°C
Solubility: Miscible with water, ethanol, and acetone
Vapor Pressure: 0.1 mm Hg at 20°C
pH: Neutral (5-7 for aqueous solution)
Viscosity: High, varies by temperature

Stability and Reactivity

Stability: Stable under normal conditions of temperature and pressure
Incompatible Materials: Strong oxidizers, strong acids, may cause reactive hazards on contact.
Decomposition Products: Carbon monoxide, carbon dioxide, possible hydrocarbon fragments if severely overheated.
Conditions to Avoid: Avoid heat, open flames, prolonged exposure to strong sunlight.

Toxicological Information

Acute Toxicity: Low oral toxicity, LD50 (rat) approx. 20-34 g/kg
Skin Irritation: Prolonged or repeated contact can lead to mild irritation in sensitive individuals
Eye Irritation: May cause temporary discomfort, redness, watering
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity at normal workplace exposure levels
Routes of Exposure: Inhalation, ingestion, skin and eye contact

Ecological Information

Ecotoxicity: Low toxicity to aquatic life (LC50 for fish > 10,000 mg/L over 96 hours)
Mobility: Completely soluble in water, freely mobile, low bioaccumulation expected
Persistence and Degradability: Biodegradable—microorganisms rapidly break down in wastewater treatment
Bioaccumulative Potential: Not likely to accumulate in aquatic species
Other Adverse Effects: Generally considered safe; large spills could cause oxygen depletion in water bodies due to high biological oxygen demand on degradation

Disposal Considerations

Waste Disposal: Dispose of contents and container in accordance with local, regional, and national regulations; offer surplus and non-recyclable solutions to a licensed disposal company
Packaging: Rinse empty containers with water before recycling or disposal, avoid landfill if recycling options exist
Special Requirements: Prevent spillage from reaching drains and waterways, use licensed chemical waste contractors if available

Transport Information

Land Transport (ADR/RID): Not classified as hazardous
Sea Transport (IMDG): Not classified as dangerous for transport
Air Transport (IATA): Not considered hazardous for air cargo
Proper Shipping Name: Propylene Glycol
UN Number: Not assigned
Packing Group: Not regulated

Regulatory Information

International Regulations: No specific category under GHS, not included in SVHC (Substances of Very High Concern) lists
Inventory Listings: Compliant with regulations in the US (TSCA), EU (EINECS/ELINCS), Canada (DSL), Australia (AICS), Japan (ENCS), China (IECSC)
Other Labeling: Label with product identifier, name of supplier, basic handling comments, date of preparation as best practice
SARA Title III (US): Not regulated under Sections 302, 304, 313