Product Name: Metaraminol Tartrate
Chemical Name: (1R,2S)-2-amino-1-(3-hydroxyphenyl)propan-1-ol hydrogen tartrate
Synonyms: Aramine tartrate
Recommended Use: Pharmaceutical vasopressor agent
Manufacturer: Pharmaceutical injectable drug supplier
Emergency Contact: Refer to local poison control center or manufacturer
CAS Number: 33402-34-3
Molecular Formula: C9H13NO2•C4H6O6
Molecular Weight: 339.33 g/mol
GHS Classification: Not classifiable as hazardous under GHS criteria for most laboratory quantities
Label Elements: None required for pharmaceutical reference use
Physical Hazards: Non-flammable, powder or crystalline solid
Health Hazards: Toxic if ingested in large amounts, may cause cardiovascular stimulation, may cause headache, tremor, restlessness, hypertension
Environmental Hazards: Avoid large releases to natural waterways, not persistent or bioaccumulative in soil
Signal Word: None
Precautionary Statements: Use pharmaceutical handling protocols – do not ingest, avoid skin and eye contact
Routes of Exposure: Oral, dermal, inhalation, ocular
Main Ingredient: Metaraminol Tartrate
Chemical Structure: Aromatic phenol and ethylamine moiety
Concentration: 100% (for reagent or pharmaceutical powder)
Impurities: Pharmaceutical grade compounds typically contain not more than 0.5% related substances
Formulation: Injectable or oral powder, lyophilized form or solution in ampoules
Stabilizers/Preservatives: None added for reference standards
Inhalation: Move individual to fresh air, provide oxygen if breathing becomes difficult, seek medical attention for persistent symptoms
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, consult poison control or physician
Skin Contact: Wash affected area with soap and water for at least 15 minutes, remove contaminated clothing, seek medical help for persistent irritation
Eye Contact: Rinse eyes carefully with water for at least 15 minutes while holding eyelids apart, seek immediate medical advice
Notes for Doctors: Treat symptomatically, monitor cardiovascular status
Suitable Extinguishing Media: Use water spray, CO2, dry chemical or foam extinguishers
Unsuitable Media: Avoid high pressure water streams that may spread powder
Special Hazards: Dust can build up and present a minor combustion hazard in rare cases; decomposition may produce carbon oxides and nitrogen oxides
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Special Procedures: Prevent contamination of water sources; control runoff if possible
Personal Precautions: Wear suitable gloves, goggles, and disposable gown; avoid dust formation and inhalation
Emergency Procedures: Ventilate area, avoid breathing dust, evacuate unnecessary personnel
Containment: Sweep or scoop up material using non-sparking tools, place in labeled containers for disposal
Cleanup Methods: Wash spill area thoroughly with water after removal of bulk material, dispose of waste by regulatory guidelines
Handling Precautions: Handle in clean, ventilated space with good laboratory hygiene; avoid direct contact or inhalation; use appropriate PPE
Hygienic Measures: Wash hands after handling, keep work area clean
Storage Conditions: Store in well-closed container at controlled room temperature, away from incompatible substances such as oxidizers
Incompatibilities: Avoid excessive heat, moisture, and light; do not store near acids or strong bases
Storage Life: Check product expiration date or retest period as assigned by manufacturer
Control Parameters: No official workplace exposure limits established for this compound
Engineering Controls: Use local exhaust ventilation or work within fume hood for bulk handling
Respiratory Protection: NIOSH-approved dust mask for handling dry powders
Eye/Face Protection: Safety goggles or face shield
Skin Protection: Laboratory coat and impermeable gloves
Other Protection: Use disposable shoe covers for large-scale handling
General Precautions: Remove contaminated clothing; avoid eating, drinking, or smoking in handling area
Appearance: White to off-white crystalline powder
Odor: Odorless
pH: Approximately 3.5-5.0 (10% aqueous solution)
Melting Point: 169°C - 172°C (decomposes)
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water, slightly soluble in alcohol
Relative Density: Approximately 1.45 g/cm³
Partition Coefficient (octanol/water): Not determined
Vapor Pressure: Negligible
Flash Point: Not flammable
Auto-Ignition Temperature: No data
Explosive Properties: Not considered explosive
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: May react with strong oxidizing agents
Conditions to Avoid: Excess heat, moisture, direct sunlight
Decomposition Products: Produces oxides of carbon and nitrogen if heated to decomposition
Hazardous Reactions: No hazardous polymerization anticipated
Acute Toxicity: LD50 (rat, oral) estimated >200 mg/kg
Chronic Effects: Prolonged exposure may affect cardiovascular system; possible hypertension, tachycardia
Routes of Exposure: Oral, inhalation, dermal, ocular
Irritation: May irritate skin and eyes
Mutagenicity/Carcinogenicity: No data indicating carcinogenicity; not listed as carcinogen by IARC, NTP, or OSHA
Reproductive Effects: Limited animal data, monitor pregnant individuals for effects
Sensitization: Not reported in standard handling
Medical Conditions Aggravated: Individuals with hypertension or cardiac arrhythmias might experience effects at lower exposure
Ecotoxicity: Not expected to be harmful to aquatic organisms at low concentrations; avoid large discharges
Persistence and Degradability: Readily biodegradable in soil and water
Bioaccumulation Potential: Low, compound does not persist in tissue
Mobility in Soil: Expected to be mobile in aqueous media due to water solubility
Other Adverse Effects: Avoid releasing to drains; pharmacologically active compounds should not reach water bodies
Waste Treatment Methods: Dispose of unused material as pharmaceutical waste through incineration or hazardous waste facility
Contaminated Packaging: Wash thoroughly before disposal or, if contaminated, treat as hazardous waste
Precautions: Do not dispose of in municipal trash or by draining into water systems
Disposal Authorization: Follow local, regional, and national regulations for controlled substances and pharmaceutical products
UN Number: Not regulated as dangerous good for transport
UN Proper Shipping Name: Not classified
Transport Hazard Class: Not applicable
Packing Group: Not regulated
Environmental Hazards: Not a marine pollutant
Special Precautions: Keep in original packaging, protect from excessive heat and direct sunlight during transport
Regulations: Transport in compliance with Good Distribution Practice guidelines for pharmaceuticals
US TSCA: Not listed for non-industrial use
EU REACH: Not specifically registered; use restricted to pharmaceutical applications
OSHA Hazard Communication: Not classified as hazardous for labeling, follow pharmaceutical handling standards
SARA Title III: Not subject to reporting requirements
WHMIS (Canada): Not controlled
Other Regulations: Handle and store according to FDA, EMA, and USP quality requirements; prescription drug regulations apply for clinical or research use
Product Statement: For use by qualified personnel only, not for general or non-pharmaceutical purposes
Providing high-quality chemical products and logistics solutions for global trade partners.
