Material Safety Data Sheet – Manganese Gluconate Dihydrate USP/FCC (Vegan/Vegetarian)

Identification

Product Name: Manganese Gluconate Dihydrate USP/FCC
Synonyms: Manganese(II) gluconate dihydrate
CAS Number: 6485-39-8
Molecular Formula: C12H22MnO14 · 2H2O
Molecular Weight: 481.27 g/mol
Recommended Use: Nutritional supplements, food additive, pharmaceutical ingredient
Supplier Details: [Insert company name, address, emergency contact number]
Emergency Phone Number: [Insert emergency response number]

Hazard Identification

GHS Classification: Slightly hazardous, Eye Irritant (Category 2A), Skin Irritant (Category 3), Specific Target Organ Toxicity - Repeated Exposure (Category 2)
Signal Word: Warning
Hazard Statements: May cause mild eye and skin irritation, may be harmful if inhaled or swallowed in large quantities, prolonged exposure may cause manganese toxicity affecting the central nervous system
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust, wash thoroughly after handling, wear protective equipment, avoid release to environment

Composition / Information on Ingredients

Chemical Name: Manganese Gluconate Dihydrate
Common Name: Manganese(II) gluconate dihydrate
CAS Number: 6485-39-8
EC Number: 229-022-6
Concentration: ≥ 98%
Impurities/Additives: None declared, suitable for vegan/vegetarian use

First Aid Measures

Inhalation: Move person to fresh air, keep at rest, seek medical attention if symptoms develop such as cough, dizziness or irritation
Skin Contact: Remove contaminated clothing, wash affected area with soap and plenty of water, seek medical help if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, consult physician if discomfort continues
Ingestion: Rinse mouth thoroughly, never give anything by mouth to an unconscious person, contact physician if large amounts are ingested or if feeling unwell
Most important symptoms: Irritation, coughing, headache, stomach upset, no delayed effects expected at recommended dosages but chronic overexposure can lead to manganese toxicity symptoms

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical powder, foam, carbon dioxide
Unsuitable Extinguishing Media: None identified in normal situations
Special Hazards: Decomposition releases carbon oxides and manganese oxides at high temperatures
Protective Equipment: Firefighters should wear full protective gear and self-contained breathing apparatus
Other Information: Prevent fire-fighting water runoff from entering drains or water courses

Accidental Release Measures

Personal Protection: Use recommended PPE including gloves, goggles, dust mask, work in a well-ventilated area
Environmental Precautions: Prevent spill from entering sewers or waterways, contain spill with inert material such as sand
Cleanup Methods: Sweep up and collect in appropriate container for disposal, avoid creating airborne dust, clean area thoroughly with water after material removal
Other Precautions: Dispose of in accordance with local, regional, national regulations

Handling and Storage

Handling: Keep container tightly closed, use with adequate ventilation, avoid dust formation, practice good hygiene and wash hands before eating or drinking, do not eat, drink or smoke in work area
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers or acids, protect container from physical damage, keep out of reach of children

Exposure Controls and Personal Protection

Exposure Limits: OSHA PEL: Not established, ACGIH TLV for manganese compounds: 0.02 mg/m³ (respirable), 0.1 mg/m³ (inhalable fraction), workplace exposure limits may vary by country
Engineering Controls: Use local exhaust ventilation or process enclosure to control airborne dust levels
Personal Protective Equipment: Protective gloves (nitrile or suitable alternative), safety glasses or chemical goggles, dust mask or particulate respirator (NIOSH-approved for airborne manganese if dust exceeds limits), protective clothing for prolonged exposure
Hygiene Measures: Wash thoroughly after handling, keep work clothing separate from other clothing

Physical and Chemical Properties

Appearance: Fine, light pink to pale brown crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 5.5 – 7.5 (5% solution in water)
Melting Point/Freezing Point: Not established due to decomposition
Boiling Point: Not applicable
Flash Point: Not available
Evaporation Rate: Not applicable
Flammability: Non-flammable
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Relative Density: Approximately 2.1 g/cm³
Solubility: Soluble in water, slightly soluble in ethanol
Partition Coefficient: Not available
Auto-ignition Temperature: Not applicable
Decomposition Temperature: >200°C
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, sensitive to moisture
Possibility of Hazardous Reactions: None under normal processing
Incompatible Materials: Strong acids, strong oxidizers
Hazardous Decomposition Products: Carbon oxides, Manganese oxides
Conditions to Avoid: High humidity, excessive heat

Toxicological Information

Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Low oral toxicity, may cause mild irritation to eyes and skin, ingestion in large amounts may cause abdominal pain and vomiting
Chronic Toxicity: Prolonged excessive exposure may result in impaired neurological function (manganism), symptoms could include tremors, difficulty walking, mood disturbances
Carcinogenicity: Not identified as carcinogenic (IARC, NTP, OSHA)
Mutagenicity: No data indicating mutagenic effects
Reproductive Toxicity: Not expected at typical intake, high doses in animal studies may affect fertility
Other Data: Manganese is an essential nutrient but excessive chronic exposure has known systemic health risks

Ecological Information

Ecotoxicity: Low acute toxicity for aquatic organisms at dilution likely for food/pharma use, high concentrations may be hazardous to aquatic life
Persistence and Degradability: Biodegradable, gluconate moiety degrades in the environment
Bioaccumulative Potential: Low, not likely to bioaccumulate in aquatic organisms
Mobility in Soil: Expected to have moderate mobility due to water solubility
Other Data: Avoid large-scale release into environment, prevent entry into waterways and public sewers

Disposal Considerations

Waste Disposal Methods: Dispose in accordance with federal, state and local regulations, small quantities can be washed away with ample water, larger quantities require disposal at approved chemical waste facilities
Contaminated Packaging: Rinse thoroughly before recycling or disposal
Special Precautions: Do not incinerate closed containers, avoid landfill disposal if possible

Transport Information

UN Number: Not regulated
Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not applicable
Special Precautions: Avoid creating dust during shipment, ensure packaging prevents moisture uptake

Regulatory Information

US TSCA: Listed
EU EINECS/ELINCS: Listed
Food Additive Status: Compliant with relevant FCC/USP and food safety regulations as nutritional supplement ingredient
GHS Labeling: Required if supplied in large packages
Other Regulations: Not subject to SARA Section 313 reporting, not a controlled substance under DOT, IATA or IMDG, always check local, state and national regulations for additional compliance requirements