Product Name: Levalbuterol tartrate
Synonyms: (R)-Albuterol tartrate, Xopenex (brand), Levosalbutamol tartrate
Chemical Family: Adrenergic beta-2 agonist
Manufacturer: Refer to label or packaging for supplier details
Emergency Phone Number: Refer to local poison control or manufacturer
Recommended Use: Pharmaceutical active, bronchodilator for respiratory relief
Restrictions on Use: For healthcare professional dispensing only, not for general public without prescription
Classification: Not classified as hazardous under OSHA Hazard Communication Standard (29 CFR 1910.1200)
GHS Label Elements: Not required
Main Hazards: May cause allergic reaction in sensitive people. Potential to trigger asthma-like symptoms, eye irritation, mild skin reaction. Not acutely toxic in small quantities. Large exposure can affect cardiac rhythm and muscle tremors in overdose situations.
Signal Word: Not required
Hazard Statements: Exposure to powder or solution may aggravate pre-existing pulmonary conditions.
Chemical Name: Levalbuterol tartrate
Molecular Formula: C13H21NO3 · C4H6O6
Molecular Weight: 628.71 g/mol
Purity: > 98% (as typically provided by USP suppliers)
CAS Number: 138528-85-1
Other Ingredients: None in pure API form; finished products may contain excipients
Inhalation: Move to fresh air. If symptoms develop, seek medical help. Continuous coughing or difficulty breathing requires immediate medical attention.
Skin Contact: Wash exposed skin with plenty of soap and water. If irritation or allergic reaction persists, consult a doctor.
Eye Contact: Flush eyes for at least 15 minutes with water. Remove contact lenses if present and easy to do. Seek medical help if discomfort remains.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical care if large quantity swallowed or if symptoms like palpitations, tremor, or dizziness develop.
Advice to Physicians: Treat symptomatically, monitor vital signs and cardiac rhythm, consider beta-blockers if patient develops tachycardia after large exposure.
Suitable Extinguishing Media: Use water spray, foam, dry chemical powder, or carbon dioxide for small fires.
Special Hazards: Burning material produces toxic gases such as nitrogen oxides, carbon monoxide, and carbon dioxide. Powder dust may pose minor explosion risk in confined space.
Protective Equipment: Firefighters use self-contained breathing apparatus and full protective gear. Limit exposure through open flames.
Specific Methods: Prevent runoff from firefighting to sewers and waterways, contain spill if possible.
Personal Precautions: Use gloves, lab coat, and N95 or higher mask. Limit inhalation, skin or eye exposure. Evacuate unnecessary personnel.
Environmental Precautions: Prevent entry to drains or surface water. Notify authorities for significant spills.
Clean-Up Method: Absorb dry powder or solution with inert material like sand, then sweep up. Wash area with mild detergent solution. Dispose in chemical waste container. Avoid generating dust.
Handling: Employ closed-system transfer or containment if powder is handled in quantity. Avoid breathing dust or vapor. Keep away from food, drink, and animal feed.
Storage: Store at 20-25°C (68-77°F), control humidity and direct sunlight. Keep container tightly closed. Secure from unauthorized use.
Conditions to Avoid: Heat, flame, and moisture may degrade active compound.
Occupational Exposure Limit: Not established for Levalbuterol tartrate. Minimize dust generation as a precaution.
Engineering Controls: Use local exhaust or general ventilation to avoid airborne concentrations.
Personal Protective Equipment: Safety goggles, disposable gloves, lab coat. NIOSH-approved respirator if exposure exceeds minimal or in case of spill.
Additional Measures: Use good industrial hygiene, wash hands after handling. Remove contaminated clothing for professional cleaning or disposal.
Appearance: White or almost white crystalline powder
Odor: Odorless
Odor Threshold: Not established
pH: 4-5 (1% solution in water)
Melting Point: Decomposes > 196°C
Boiling Point: Not applicable
Solubility: Freely soluble in water, slightly soluble in ethanol
Vapor Pressure: Negligible
Relative Density: Not available
Partition Coefficient: Not determined
Other Properties: Stable as a solid under recommended transport and storage. Not volatile.
Chemical Stability: Chemically stable under normal handling and storage
Reactivity: No hazardous reactivity anticipated under normal conditions
Incompatibilities: Strong oxidizers, strong acids
Hazardous Decomposition Products: Acrid smoke, carbon monoxide, nitrogen oxides when heated to decomposition
Hazardous Polymerization: Will not occur
Routes of Exposure: Inhalation, skin absorption, ingestion
Acute Symptoms: Tremor, nervousness, palpitations, headache may occur with overdose/excess exposure
Target Organs: Heart, lungs, nervous system (due to beta-2 agonist activity)
Delayed/Chronic Effects: Risk of hypokalemia, tachycardia with prolonged large-scale exposure; rare allergic reactions (urticaria, angioedema)
Carcinogenicity: Not listed by IARC, NTP, ACGIH, or OSHA
Other Data: Extremely low toxicity by all routes in small quantities used clinically
Aquatic Toxicity: No specific data, structurally similar compounds predicted low acute aquatic toxicity
Persistence and Degradability: Not persistent; expected to degrade by hydrolysis and microbial metabolism
Bioaccumulation: Low potential
Mobility in Soil: High solubility in water, moderate mobility predicted
Other Harmful Effects: No known significant environmental risk at therapeutic volumes; large uncontrolled discharges could harm aquatic organisms
Disposal Methods: Collect all waste in sealed, labeled chemical waste containers. Incinerate at licensed facility or land fill according to national and local regulations.
Special Precautions: Do not flush to sewer. Dispose of empty packaging as regulated medical waste if contaminated.
Legal Requirement: Follow local, regional, and federal requirements for pharmaceutical chemical disposal
UN Number: Not regulated as hazardous for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Use tightly sealed original packaging. Avoid heat, shock, or damage during transit.
Labeling: Not subject to DOT, ICAO/IATA, IMDG regulations for transport of hazardous goods
Environmental Hazards: Not a marine pollutant
Occupational Safety and Health: Not subject to OSHA-specific chemical regulations. GHS labeling not required.
Inventory Listing: Check local chemical inventory for registration status.
WHMIS Classification (Canada): Not controlled
TSCA (USA): For research or pharmaceutical use only, not for general manufacturing
Other Regulations: Subject to prescription pharmaceutical controls under US FDA and other international authorities. Consult national authorities for workplace control recommendations and environmental reporting obligations.
Providing high-quality chemical products and logistics solutions for global trade partners.
