Product Name: L-(+)-Threo-2-Amino-1-Phenyl-1,3-Propanediol
Synonyms: L-Threo-2-Amino-1-Phenyl-1,3-Propanediol, L-threo-APD
Chemical Formula: C9H13NO2
Molecular Weight: 167.21 g/mol
Recommended Use: Research, development, laboratory reagent in chemical and pharmaceutical industries
Manufacturer: Refer to sourcing distributor or direct supplier documentation
Emergency Contact Number: Refer to local poison control, emergency medical, and fire services
CAS Number: 3188-13-2
UN Number: Not regulated under most shipping classifications
GHS Classification: Not classified as hazardous under GHS criteria for physical, health, or environmental hazards
Signal Word: None assigned
Hazard Statements: May cause irritation to eyes, skin, or respiratory tract on direct contact or inhalation
Precautionary Statements: Wear protective gloves and equipment; avoid dust inhalation; wash thoroughly after handling
Potential Health Effects: Eyes: mild-moderate irritation; Skin: mild redness; Inhalation: respiratory irritation if dust forms; Ingestion: nausea, discomfort
Symptoms of Overexposure: Headache, dizziness, mild gastrointestinal upset, coughing
Chemical Name: L-(+)-Threo-2-Amino-1-Phenyl-1,3-Propanediol
Purity: ≥98% (lab reagent grade)
Impurities: Trace amounts (≤2%) of related phenylated amino alcohols or residual solvents depending on supplier documentation
Other Components: Does not contain hazardous stabilizers, diluents, or preservatives per SDS requirements
Inhalation: Move affected person to fresh air, support breathing if necessary, seek medical attention for persistent symptoms
Skin Contact: Immediately wash exposed skin with mild soap and plenty of water, remove contaminated clothing, consult physician if irritation persists
Eye Contact: Rinse thoroughly with gentle stream of clean water for at least 15 minutes, seek medical advice for prolonged irritation
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical evaluation for large accidental intake
Most Important Symptoms: Irritation, mild inflammation at contact sites, no known acute systemic toxicity at laboratory scale use
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam, water spray for larger fires
Specific Hazards: Combustion produces carbon oxides (CO, CO₂), nitrogen oxides, unidentified organic fragments
Protective Equipment: Wear self-contained breathing apparatus and fire-resistant clothing to avoid inhaling combustion byproducts
Explosion Hazard: Fine organic dust can present a fire/explosion risk under rare high-dust concentration conditions
Special Procedures: Remain upwind during suppression, avoid runoff contamination, ventilate fire area post-extinguishing
Personal Protection: Use gloves, goggles, and dust mask or respirator if powder disperses in air
Spill Management: Sweep up with minimum dust generation, collect in labeled waste container, avoid contaminating water sources
Environmental Precautions: Prevent entry to soil, surface waters, or sewage; notify appropriate regulatory authorities if significant release occurs
Cleanup Methods: Moisten powder to avoid dust, use inert absorbent for solutions, wash spill area thoroughly post-collection
Handling: Control dust, avoid breathing powder, use only in ventilated area, protect from physical damage
Storage Conditions: Keep tightly sealed in original container, store at controlled room temperature (15-25°C), protect from moisture and strong oxidants
Incompatibilities: Strong acids, strong bases, oxidizing agents, reducing agents
Special Storage Needs: Label container clearly, restrict access to authorized trained personnel, maintain inventory logs for laboratory use
Occupational Exposure Limits: No established limits under OSHA, NIOSH, or ACGIH standards
Engineering Controls: Use chemical fume hood or local exhaust if airborne dust forms during weighing or transfer
Personal Protection: Gloves (nitrile or PVC), safety goggles, lightweight laboratory coat, NIOSH-approved respirator for airborne powder
Hygiene Measures: Prevent contact with skin and eyes, remove contaminated clothing, wash hands with soap, avoid eating or drinking in the lab
Appearance: Off-white to pale yellow crystalline powder
Odor: Minimal or faint characteristic odor (not pungent)
pH (1% solution): Neutral to weakly basic
Melting Point: 156-158°C
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not determined, likely above 150°C based on comparable aromatic aminoalcohols
Water Solubility: Moderately soluble
Partition Coefficient (Log Pow): Not measured directly, expected low-moderate based on molecular structure
Vapor Pressure: Negligible at ambient temperature
Density: Estimated 1.2-1.3 g/cm³
Other Data: Stable under recommended storage, hygroscopic if exposed to air
Chemical Stability: Stable for extended periods in dry, closed containers at ambient temperature
Reactivity: Does not react vigorously with air or water, but contact with strong acids/bases or oxidizers can degrade structure
Hazardous Decomposition: Unidentified organic vapors, carbon monoxide, carbon dioxide may form if heated to decomposition
Polymerization: No hazardous polymerization reported
Special Conditions to Avoid: Prolonged high temperature, moisture, incompatible chemicals
Acute Toxicity: Not reported to have acute toxicity based on available data on structure and analogs
Skin Irritation: Mild to moderate, avoid prolonged or repeated contact
Eye Irritation: Mild to moderate; flush eyes thoroughly if exposed
Inhalation: Irritation of upper respiratory tract can occur if dust concentrations are high
Ingestion: Can cause gastrointestinal upset at significant doses
Chronic Effects: No known long-term toxicity with current usage patterns in laboratory or chemical research
Sensitization: No evidence for skin or respiratory sensitization based on related compounds
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity/Genotoxicity: No available data indicate genotoxic risk
Remark: Good laboratory safety precautions minimize risk of accidental overexposure
Ecotoxicity: Not expected to pose significant risk to aquatic life at laboratory levels of discharge
Persistence and Degradability: Degradable in soil and water, limited bioaccumulation
Bioaccumulation: Not expected based on chemical structure
Mobility in Soil: Moderate solubility, low mobility due to adsorption to organic matter
Other Information: Avoid uncontrolled release to the environment, maintain proper disposal practices at laboratory and pilot-plant scale
Waste Treatment: Handle as non-hazardous organic waste, incinerate in accordance with local regulations or deliver to authorized chemical waste processing partners
Contaminated Packaging: Rinse and dispose in accordance with local, state, and national laws governing non-hazardous chemical containers
Sewage Disposal: Do not flush into municipal drains or watercourses
Special Precautions: Collect wastes in properly labeled containers, keep away from incompatible wastes, limit volumes per primary container
DOT Classification: Not regulated as hazardous material
IMDG: Not classified as a marine pollutant or hazardous under IMDG code
IATA: Not subject to dangerous goods transport regulations
UN Number: None assigned
Packing Group: Not applicable
Precautionary Transport Measures: Use sealed containers, prevent shifting or breakage, secure packaging against physical damage, include correct shipping papers
TSCA Status: Listed or exempted per US EPA TSCA Inventory
OSHA Hazard Communication: Not regulated as a hazardous material
SARA Title III: Not subject to SARA hazard categories, no reporting threshold exceeded
REACH Status: Not registered for high volume industrial use; consult supplier for current pre-registration/compliance statements
California Proposition 65: Does not contain chemicals subject to Proposition 65 labeling
Other Statutory Information: Comply with relevant state, national, and international chemical regulations, provide safety training to all users before workplace handling
Providing high-quality chemical products and logistics solutions for global trade partners.
