Product Name: L-(+)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Synonyms: None
Chemical Family: Amino alcohols
Recommended Use: Laboratory research, synthesis, chemical studies
Supplier: Manufacturer and distributor contact details required for legal and emergency communications
Emergency Phone: Country-specific emergency hotline, CHEMTREC or equivalent
CAS Number: 3446-89-7
GHS Classification: Acute toxicity (oral, dermal), skin irritation, serious eye irritation, specific target organ toxicity (single exposure)
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes skin and eye irritation. May cause damage to organs through single exposure. Toxic to aquatic life.
Pictograms: Exclamation mark, health hazard, aquatic toxicity
Precautionary Statements: Avoid breathing dust. Wear protective gloves, clothing, and eye/face protection. Wash thoroughly after handling. Do not eat, drink, or smoke during use.
Chemical Name: L-(+)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
CAS Number: 3446-89-7
Concentration: 98% or greater, with trace impurities below regulated thresholds
Impurities: Analytical trace, as determined by batch control and supplier testing, specifics provided on batch documentation
Inhalation: Move affected person to fresh air. Seek medical attention for difficulties in breathing or persistent discomfort. Remove from exposure source.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water for at least 15 minutes. Seek medical advice for irritation.
Eye Contact: Rinse eyes carefully for at least 15 minutes, lifting eyelids. Contact a medical professional promptly.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting. Get medical help immediately.
Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide. Avoid direct water stream if possible.
Hazardous Combustion Products: Nitrogen oxides, carbon monoxide, dioxide, and toxic fumes released at high temperatures.
Special Firefighting Procedures: Wear full protective equipment and self-contained breathing apparatus. Remove containers from area if it is safe.
Unusual Fire and Explosion Hazards: Dust accumulation may pose explosion hazard. Cool adjacent containers to reduce risk.
Personal Precautions: Wear proper PPE (gloves, eye protection, respirator in poorly ventilated areas). Isolate spill area.
Environmental Precautions: Prevent entry to drains and natural waterways. Notify relevant authorities in line with regulatory rules.
Containment and Cleanup: Scoop solid spills into suitable labeled containers for disposal. Wipe or mop contaminated surfaces with a suitable cleaning solvent. Ensure adequate ventilation during cleanup.
Safe Handling: Avoid contact with skin, eyes, and clothing. Use only in areas with appropriate ventilation. Practice good hygiene after handling.
Storage Requirements: Secure containers tightly closed and store in a cool, dry, and well-ventilated location. Separate from incompatible materials: strong oxidizers, acids, and bases. Protect from moisture and heat sources.
Incompatible Materials: Oxidizing agents, strong acids, strong bases.
Exposure Limits: No occupational exposure limits established for this compound; use general chemical control procedures.
Engineering Controls: Use fume hood or equivalent local exhaust. Maintain proper ventilation in storage and handling areas.
Personal Protection Equipment (PPE): Use nitrile gloves, chemical-resistant protective clothing, and eye/face protection (goggles). For airborne dust, wear NIOSH-approved respirator.
Form: Crystalline solid
Color: Pale-yellow to orange
Odor: Odorless
Melting Point: 199 - 203°C (specific laboratory tested range)
Boiling Point: Not determined
Solubility: Soluble in water, methanol, and ethanol; poor solubility in non-polar organic solvents
pH: Slightly acidic
Flash Point: Not applicable (non-volatile solid)
Vapor Pressure: Negligible
Specific Gravity: Data not available
Chemical Stability: Stable under standard ambient conditions of temperature and pressure, within original packaging.
Reactivity: Reacts with strong oxidizers, acids, and reducing agents.
Hazardous Decomposition: Yields nitrogen oxides, carbon monoxide, and other potentially hazardous vapors if heated beyond decomposition.
Polymerization: Does not polymerize
Conditions to Avoid: Prolonged heat, open flame, direct sunlight, moisture
Routes of Exposure: Inhalation, ingestion, dermal, and ocular contact
Acute Oral Toxicity: Harmful if swallowed (category 4)
Acute Dermal Toxicity: Irritating to skin upon direct contact
Eye Effects: Causes significant eye irritation
Respiratory Effects: Prolonged dust inhalation may cause respiratory irritation
Chronic Toxicity: Not classified as carcinogenic or teratogenic by internationally recognized agencies, though data remain limited. Seek safer alternatives for pregnant women or those with reactive airway disease.
Symptoms of Exposure: Nausea, headache, eye redness, coughing, skin redness or rash.
Aquatic Toxicity: Toxic to freshwater and aquatic life upon release
Persistence and Degradability: Not readily biodegradable; lingers in water and soil
Bioaccumulation Potential: Limited data; not expected to bioaccumulate significantly due to polar functional groups
Mobility: Product demonstrates moderate mobility in soil, with high solubility favoring migration to groundwater in uncontained spills
Other Adverse Effects: Do not allow large-scale release to sewerage or waterways; possible risk to terrestrial fauna if mishandled.
Disposal Method: Dispose of through licensed chemical waste disposal provider. Consult local, regional, and federal regulations for hazardous waste segmentation.
Container Disposal: Empty containers may retain residue; treat as hazardous chemical waste. Decontaminate or incinerate under controlled conditions.
Precautions: Never discharge to public sewage or landfill. Keep in secure, labeled containers until final disposal. Avoid transferring to general waste streams.
UN Number: Not classified under current UN transport guidelines
Packaging Group: No specific code but handle as potentially harmful solid
Transport Hazard Class: No assigned class; use category for toxic solids if crossing borders
Marine Pollutant: Not specifically listed, advise precaution in marine environments
Special Transport Precautions: Protect containers from physical damage; avoid stacking; provide documentation to carriers regarding potential hazards.
TSCA Status: Listed or subject to the Significant New Use Rule (SNUR) in the US
EU REACH Registration: Registration expected for volumes above one ton per year; check updated ECHA lists
OSHA/HCS: Considered hazardous under US HCS
Other Regulations: Subject to workplace safety and chemical hygiene rules in laboratory and industrial settings in most countries; special disposal and reporting required in the European Union, Japan, and Canada.
Labeling Requirements: Conform to GHS, OSHA, and country-specific right-to-know laws; hazard pictograms, signal word, and hazard/precautionary statements displayed clearly on packaging.
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