Product Name: l-Noradrenaline tartrate
Synonyms: Norepinephrine bitartrate, Levonorepinephrine hydrogen tartrate
CAS Number: 108341-18-0
Recommended Use: Laboratory research, pharmaceutical intermediate
Manufacturer/Supplier: Available from various chemical suppliers for research purposes
Emergency Contact: Access local poison control or emergency numbers promptly for incidents involving this chemical
GHS Classification: Acute toxicity (oral, dermal, inhalation) Category 3, Eye irritation Category 2A, Skin irritation Category 2
Hazard Statements: Toxic if swallowed, may cause skin irritation and serious eye irritation, can cause respiratory tract irritation
Signal Word: Danger
Pictograms: Skull and crossbones, exclamation mark
Other Hazards: May affect heart rate, blood pressure, and neurological functions upon exposure
Chemical Name: l-Noradrenaline tartrate
CAS Number: 108341-18-0
EC Number: Not listed
Purity: At least 98% (varies with supplier)
Relevant Impurities: Minor byproducts from synthesis/oil or moisture content may be present in small quantities
Inhalation: Move person to fresh air, keep at rest, seek immediate medical attention for difficulty breathing or persistent symptoms
Skin Contact: Remove contaminated clothing, wash exposed skin thoroughly with water and soap for several minutes, seek medical advice for persistent effects
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to handle, continue rinsing and get prompt medical assessment
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical attention and provide medical personnel with all available product information
Advice for Medical Personnel: Treat symptomatically, be aware of possible cardiac effects and potential for rapid systemic absorption
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide or foam
Hazards from Combustion: May release toxic fumes like nitrogen oxides, carbon monoxide, carbon dioxide and other hazardous decomposition products
Protective Equipment: Firefighters should use self-contained breathing apparatus and complete protective gear
Additional Information: Prevent runoff from entering drains, use water spray to keep containers cool near fire area, watch for aggressive fire behavior in chemical storage situations
Personal Precautions: Evacuate unprotected personnel, wear gloves, lab coat, goggles, and suitable respirator if airborne dust or vapor may be generated
Environmental Precautions: Prevent further leakage or spillage if safe to do so, avoid discharge into the environment and watercourses
Containment and Cleaning: Scoop or sweep up spilled material, place in sealed chemical waste container for disposal, ventilate area well and decontaminate surfaces with water and detergent
Handling: Use only in well-ventilated environments, avoid contact with skin and eyes, minimize dust and aerosol generation, practice good personal hygiene after handling
Storage Conditions: Store in tightly closed container, keep away from incompatible materials, store in cool, dry, ventilated place away from direct sunlight
Incompatible Materials: Strong oxidizers, acids, bases, reactive metals
Handling Advice: Implement secondary containment and lock access to trained personnel only, label all containers clearly
Engineering Controls: Use chemical fume hood, ensure local exhaust ventilation at work site
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, protective lab coat, and respiratory protection when significant dust or vapors are possible
Exposure Limits: No established occupational limit, observe general chemical safety practices
Hygiene Measures: Wash hands thoroughly after handling, avoid eating, drinking, or smoking in work area
Appearance: White to off-white crystalline powder
Odor: Odorless
Molecular Formula: C8H11NO3·C4H6O6
Molecular Weight: 337.3 g/mol
Melting Point: Typically reported as 218–221°C
Solubility: Soluble in water, practically insoluble in organic solvents
pH (solution): 3–5 (in water)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not readily flammable
Vapor Pressure: Not available
Density: Approximately 1.4 g/cm³
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Excessive heat, light, moisture, incompatible substances
Hazardous Decomposition: Nitrogen oxides, carbon monoxide, carbon dioxide, irritating fumes released in fire or on decomposition
Reactivity: Not highly reactive in standard storage but reacts with strong oxidizers and acids
Polymerization: Avoid conditions that may promote hazardous reactions
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; effects include headache, increased heart rate, hypertension, restlessness, skin and eye irritation
Chronic Effects: Continuous or repeated exposure may result in nervous system effects; long-term organ impact not established
Routes of Exposure: Ingestion, inhalation, dermal, ocular
Symptoms: Palpitations, tremors, anxiety, irritability, nausea, vomiting, rapid pulse, cardiovascular complications in severe cases
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA
Mutagenicity: No relevant data observed in available studies
Reproductive Toxicity: Data insufficient; avoid exposure if pregnant or breastfeeding
Aquatic Toxicity: May pose a hazard to aquatic organisms in significant quantities
Persistence / Degradability: Likely to degrade in environment but persistence data limited
Bioaccumulation: Low potential for bioaccumulation expected
Mobility: Readily soluble in water; may migrate in aquatic environments
Environmental Precautions: Avoid spills or release into soil and waterways, prevent chemical waste from entering streams or sewage
Waste Treatment: Dispose of in accordance with local, regional, and national regulations
Methods: Collect liquid and solid waste into designated containers labeled with hazard symbol, hand over to licensed hazardous waste disposal company
Contaminated Packaging: Empty containers retain chemical residue, must be disposed of as hazardous waste
Precautions: Do not discharge into environment; incineration under controlled conditions preferred over landfill for this class of compound
UN Number: Not assigned specific UN number for this compound
Proper Shipping Name: Not regulated as dangerous good under transport codes (ADR, RID, IMDG, IATA) when shipped in small quantities for laboratory use
Hazard Class: Not assigned
Packaging Requirements: Pack in secure, leak-proof, chemically resistant packaging, marked according to regulations
Special Precautions: Always handle with care and keep package documentation identifying substance for customs and regulatory compliance
Labeling: GHS-compliant hazard labeling required for shipments; appropriate warning signs and pictograms on primary and secondary containers
Chemical Inventories: Not specifically listed on US TSCA, EU REACH exempt for R&D, country-specific rules may apply
Specific Regulations: For medical and scientific research use, subject to regulations covering pharmaceutical precursors and laboratory safety
Occupational Safety: Covered under chemical safety and hazardous material regulations for laboratories and industry; compliance enforced by agencies like OSHA, EPA, and analogous authorities globally
Restrictions: Not intended for food, drug, or household use and restricted to trained professionals in controlled settings
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