Product Name: L-Dimethyl Amino Ethanol Bitartarate
Chemical Formula: C8H17NO6
CAS Number: 3164-65-6
Recommended Use: Laboratory reagents, intermediate for chemical synthesis, research applications
Synonyms: 2-(Dimethylamino)ethanol hydrogen tartrate, DMAE bitartrate
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Hazard Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Acute toxicity—oral (Category 4)
Signal Word: Warning
Pictograms: Exclamation mark
Hazard Statements: Causes eye irritation. Causes skin irritation. Harmful if swallowed.
Precautionary Statements: Wash hands thoroughly after handling. Wear protective gloves, clothing, eye, and face protection. Avoid breathing dust or vapors. If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.
Potential Health Effects: Direct contact leads to redness and discomfort in eyes or on skin. High exposure causes headaches, drowsiness, or nausea.
Chemical Name: L-Dimethyl Amino Ethanol Bitartarate
Common Name: DMAE Bitartarate
Concentration: 98–100%
Impurities: Potential traces of related tartaric acid derivatives (less than 2%)
CAS Number: 3164-65-6
EC Number: 221-623-5
Eye Contact: Immediately flush eyes with gently running water for at least 15 minutes, lifting upper and lower eyelids occasionally. Seek medical attention promptly if irritation persists.
Skin Contact: Wash contaminated skin with soap and plenty of water. Remove contaminated clothing. Get medical attention if irritation or discomfort continues.
Inhalation: Move victim to fresh air. Provide oxygen or artificial respiration if breathing is difficult. Seek medical attention if symptoms develop.
Ingestion: Rinse mouth with water. Do not induce vomiting unless advised by medical professionals. Seek medical advice immediately.
Most Important Symptoms: Eye and skin irritation, headache, dizziness, nausea in case of significant ingestion or inhalation.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Unsuitable Extinguishing Media: Direct water jet (may spread fire)
Specific Hazards: Emits toxic fumes of carbon oxides and nitrogen oxides when burned.
Special Protective Equipment: Firefighters use self-contained breathing apparatus and full protective clothing.
Fire/Explosion Hazards: Fine powders may form explosive mixtures with air; containers may rupture under intense heat.
Advice for Firefighters: Prevent run-off from reaching drains or waterways.
Personal Precautions: Evacuate unprotected personnel. Wear chemical-resistant gloves, goggles, and protective clothing. Avoid breathing dust.
Environmental Precautions: Prevent entry into drains, sewers, and waterways. Notify authorities if product contaminates the environment.
Methods for Cleanup: Sweep or vacuum up spills and place in appropriate waste disposal container. Avoid raising dust. Wash spill area thoroughly with water.
Containment: Use inert absorbent material for large spills. Dispose of according to local regulations.
Handling: Wear suitable personal protective equipment. Avoid creating dust or aerosols. Work in a well-ventilated space.
Hygiene Measures: Wash hands and face after handling. Avoid eating, drinking, or smoking in work area.
Storage Conditions: Store in tightly closed containers in a dry, cool, and well-ventilated area. Keep away from incompatible materials such as strong oxidizers and acids.
Recommended Packaging: Use non-reactive, sealed containers. Label all containers clearly.
Incompatible Materials: Strong acids, oxidizers, and bases.
Occupational Exposure Limits: No established OSHA or ACGIH limits for this compound; use general limits for nuisance dust (10 mg/m³ total, 3 mg/m³ respirable).
Engineering Controls: Use local exhaust ventilation. Mechanical ventilation recommended to minimize exposure.
Eye Protection: Safety goggles or face shield.
Skin Protection: Chemical-resistant gloves and laboratory coat.
Respiratory Protection: Approved respirator in case of inadequate ventilation or elevated airborne levels.
Workplace Monitoring: Regular air monitoring for dust and decomposition products in high-use environments.
Environmental Exposure Controls: Prevent product from reaching soil, waterways, and sewers.
Appearance: White crystalline powder
Odor: Mild, characteristic chemical
pH (solution): 4.0–5.0 (1% solution in water)
Melting Point: Approximately 165–170°C
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not readily flammable
Solubility: Soluble in water, slightly soluble in alcohol
Density: 1.4 g/cm³
Vapor Pressure: Negligible at room temperature
Partition Coefficient (n-octanol/water): Not available
Autoignition Temperature: Not established
Decomposition Temperature: Above 180°C releases toxic smoke
Viscosity: Not applicable (solid at room temperature)
Chemical Stability: Stable under recommended storage and handling conditions.
Conditions to Avoid: Excessive heat, humidity, direct sunlight.
Materials to Avoid: Strong oxidizers, acids, alkali materials.
Hazardous Decomposition Products: Emits carbon monoxide, carbon dioxide, nitrogen oxides, and other toxic byproducts on thermal decomposition.
Hazardous Polymerization: Does not occur under normal conditions.
Likely Routes of Exposure: Inhalation, skin, and eye contact; ingestion
Acute Toxicity—Oral LD50 (rat): >1000 mg/kg
Skin Corrosion/Irritation: Causes mild to moderate skin irritation
Eye Damage/Irritation: Causes significant irritation
Respiratory Sensitization: Not classified
Skin Sensitization: Not classified
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Mutagenicity: Not reported
Reproductive Toxicity: No adverse effects reported
Symptoms: Redness, discomfort, dizziness, nausea, vomiting.
Ecotoxicity: No detailed studies available; expected to have low aquatic toxicity based on structural analogs.
Persistence and Degradability: Expected to be biodegradable. Degrades in soil and water, though exact rate not documented.
Bioaccumulation: No potential for bioaccumulation predicted, low octanol-water partition coefficient.
Mobility in Soil: Readily soluble in water; mobile in aqueous environment.
Other Adverse Effects: Release to waterways can alter pH and affect aquatic organisms if uncontrolled.
Waste Treatment Methods: Dispose of contents and container in accordance with local, regional, and national regulations.
Methods of Disposal: Treat as chemical waste. Avoid discharge into drains or surface water.
Packaging Disposal: Triple rinse containers; offer for recycling if available or dispose of as hazardous waste.
Special Precautions: Incinerate waste under controlled conditions if permitted.
Legal Requirements: Follow all applicable guidelines for hazardous chemical disposal.
UN Number: Not regulated for ground, air, or sea transport under UN Model Regulations
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Not classified as marine pollutant
Transport in Bulk: No special precautions required; keep dry and sealed
Additional Information: Standard labeling and secure packaging to prevent spillage during transit.
TSCA (US): Listed
REACH (EU): Registrant notification and safety considerations apply
DSL/NDSL (Canada): Listed
Labeling Requirements: Comply with OSHA Hazard Communication Standard, CLP Regulation (EC) No 1272/2008
SARA Title III: Not subject to regulations under SARA 302, 304, 311, 312, or 313
California Prop 65: Not listed
Workplace Hazardous Materials Information System (WHMIS): D2B - Toxic material causing other toxic effects
Inventory Status: Included in most national inventories
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