Product Name: Kojic Acid Dipalmitate
Other Names: Hexadecanoic acid, 2-(hexadecyloxy)-1,3-dioxo-4H-pyran-4-yl ester
Recommended Uses: Cosmetic ingredient for skin-lightening formulations, research and laboratory use
Supplier Details: Manufacturer or distributor’s name, address, and emergency contact number as listed on packaging
Chemical Formula: C38H66O6
CAS Number: 79725-98-7
Molecular Weight: 618.92 g/mol
Classification: Not classified as hazardous under GHS for most applications
Possible Hazards: May cause skin or eye irritation on direct contact
Label Elements: Signal word: Warning; Pictograms: Exclamation mark for irritation risks
Precautionary Statements: Avoid inhalation and direct contact with skin or eyes; wash hands after handling
Acute Health Effects: Mild skin, eye, and respiratory tract irritation
Chronic Effects: Long-term effects are not widely reported in available toxicological data
Main Ingredient: Kojic Acid Dipalmitate
Concentration: 98–100%
Impurities/Additives: Trace amounts of related fatty acid esters, no significant hazardous ingredients
Ingredient Type: Pure substance
Inhalation: Remove affected person to fresh air; seek medical attention if breathing is difficult or symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with water for 15 minutes, and wash thoroughly with soap
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing
Ingestion: Rinse mouth thoroughly with water, seek medical help immediately, do not induce vomiting unless instructed by medical personnel
Advice For Medical Personnel: Symptomatic treatment
Suitable Extinguishing Media: Use foam, dry chemical, carbon dioxide, or water spray
Unsuitable Media: Avoid high-pressure water streams that may spread the material
Specific Hazards: Combustion can produce carbon monoxide, carbon dioxide, and other unidentified toxic fumes
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Special Procedures: Cool containers with water to prevent bursting from heat
Personal Precautions: Wear appropriate protective gloves, safety glasses, and face mask
Environmental Precautions: Prevent material from entering water sources, sewers, or soil
Containment Methods: Sweep up and collect spilled substance into appropriate containers for disposal
Cleanup Methods: Wipe up residue with damp absorbent material, avoid creating dust
Decontamination: Wash spill area with soap and water once solid material is removed
Safe Handling: Use in well-ventilated areas, minimize dust formation, and avoid inhaling particles
Avoid Contact: Always use personal protective equipment to limit skin and eye exposure
Hygiene Measures: Wash hands, face, and any exposed skin after handling, do not eat or drink while using this material
Storage Conditions: Store in tightly closed containers, away from light, heat sources, moisture, and strong oxidizers
Storage Temperature: Keep at room temperature (15–25°C), avoid freezing or excessive heat
Packaging Materials: Store in original packaging or compatible inert containers
Exposure Limits: No established occupational exposure limits
Engineering Controls: Use mechanical ventilation in work area, local exhaust preferred
Respiratory Protection: NIOSH-approved dust masks for dusty environments
Eye Protection: Chemical safety goggles when dust or splash potential exists
Hand Protection: Impermeable gloves (nitrile, neoprene)
Skin Protection: Lab coats or chemical-resistant apron to protect clothing and skin
Environmental Controls: Avoid release into environment, manage waste responsibly
Appearance: White to pale yellow powder
Odor: Faint, fatty odor
Odor Threshold: Not determined
pH: Not applicable in dry state
Melting Point/Freezing Point: 93–97°C
Boiling Point/Range: Not easily available due to decomposition
Flash Point: > 150°C
Evaporation Rate: Not available
Flammability: May burn when in contact with open flame
Vapor Pressure: Negligible
Vapor Density: Not determined
Relative Density: ~1.0–1.1 g/cm³
Solubility: Insoluble in water, soluble in oils and organic solvents
Partition Coefficient (log Kow): Not readily available
Autoignition Temperature: Not determined
Decomposition Temperature: Above 200°C
Viscosity: Not applicable
Chemical Stability: Stable under normal conditions of storage and use
Reactivity: Unreactive to most common substances, reacts with strong oxidizing agents
Hazardous Reactions: None under recommended conditions
Conditions to Avoid: Excessive heat, exposure to light, contact with strong oxidizers
Decomposition Products: Produces carbon monoxide, carbon dioxide upon burning
Acute Toxicity: Low toxicity, LD50 (oral, rat) expected to be high, no specific values available
Skin Corrosion/Irritation: May cause mild irritation to skin upon prolonged or repeated contact
Serious Eye Damage/Irritation: Direct eye exposure can cause redness or discomfort
Respiratory Sensitization: Dust may cause mild respiratory tract irritation
Germ Cell Mutagenicity: Not mutagenic, based on available data
Carcinogenicity: Not listed as carcinogenic by IARC, ACGIH, NTP, or OSHA
Reproductive Toxicity: No adverse reproductive effects reported in available studies
Target Organs: Not reported to target specific organ systems
Potential Health Effects: Eyes, skin, and mucous membranes may be affected by dust exposure
Ecotoxicity: No significant hazards reported at standard usage levels for cosmetic products
Mobility in Soil: Low water solubility, likely to adsorb onto soil particles
Persistence and Degradability: Environmental breakdown is slow, not readily biodegradable
Bioaccumulative Potential: Potential for bioaccumulation exists due to fat solubility
Aquatic Toxicity: Limited data, but no major harm anticipated based on typical usage rates
Waste Treatment Methods: Collect and send solid waste to approved chemical disposal facility
Unused Product: Dispose in accordance with local, regional, and national regulations for chemical waste
Contaminated Packaging: Rinse empty containers thoroughly before disposing or sending to recycler
Environmental Precautions: Do not dispose of in surface water, sewer, or general waste streams
Special Precautions: Follow guidelines for handling persistent organic pollutants as appropriate
UN Number: Not regulated for transport
UN Proper Shipping Name: Not classified
Transport Hazard Class(es): Not recognized as a hazardous material during transit
Packing Group: Not assigned
Special Precautions for User: Keep container sealed and protected from moisture and excessive heat during movement
International Transport: Complies with IATA, IMDG, and DOT regulations for non-hazardous solid chemicals
OSHA: Not specifically regulated as hazardous
TSCA: Listed
DSL/NDSL: Listed as a permitted ingredient in cosmetics
REACH: Registered for use in cosmetic applications
Other: Ensure compliance with EU Cosmetics Regulation (EC) No. 1223/2009 and local cosmetic ingredient guidelines
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