Material Safety Data Sheet: Kitasamycin Tartrate Base

Identification

Product Name: Kitasamycin Tartrate Base
Chemical Formula: C35H59NO13.C4H6O6
CAS Number: 569-61-9
Synonyms: Leucomycin tartrate, Kitasamycin propionate tartrate
Brand Names: Common in veterinary medicines and some industrial applications
Recommended Use: Antibacterial agent in veterinary settings
Manufacturer: Contact supplier or production facility for specifics
Emergency Contact: Emergency phone information supplied with each shipment
Relevant Identified Uses: Pharmaceutical intermediate, research chemical. Do not use for food, cosmetic, or household purposes.

Hazard Identification

Classification: Eye irritation, Skin irritation, Sensitizer, Respiratory hazard
GHS Label Elements: Exclamation mark, health hazard pictogram
Signal Word: Warning
Hazard Statements: H315 causes skin irritation, H319 causes serious eye irritation, H334 may cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary Statements: Avoid breathing dust or vapor, wash hands after handling, use only outdoors or in well ventilated area, wear eye protection, gloves, and mask.
Potential Health Effects: Irritates eyes and skin on direct contact, may aggravate existing respiratory conditions, sensitization on prolonged or repeated exposure
Environmental Risks: Harmful to aquatic organisms, long-term adverse effects possible in the environment

Composition / Information on Ingredients

Ingredient: Kitasamycin Tartrate
Concentration: Typically >90% by weight
Other Components: Trace residual solvents, possible sodium chloride, water (up to 5%)
Impurities: Trace levels of manufacturing by-products
Physical Form: Off-white to pale yellow powder

First Aid Measures

Inhalation: Move affected person to fresh air, keep at rest, seek immediate medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water and soap for at least 15 minutes, obtain medical attention for persistent irritation
Eye Contact: Immediately flush or rinse eye with plenty of clean water for at least 15 minutes, lifting upper and lower eyelids occasionally, seek prompt medical attention
Ingestion: Rinse mouth, do not induce vomiting, never give anything by mouth to an unconscious person, seek medical attention immediately
Notes to Physician: No specific antidote, provide symptomatic and supportive care

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide or water spray
Unusual Fire Hazards: Emits toxic fumes of carbon oxides, nitrogen oxides under fire conditions
Special Protective Equipment: Firefighters need self-contained breathing apparatus and full protective clothing
Explosion Data: Fine dust dispersed in air can ignite; take measures to prevent dust buildup
Advice for Firefighters: Approach from upwind side, keep containers cool with water spray, prevent runoff from entering drains or watercourses
Combustion Products: Oxides of carbon, nitrogen, unidentified organic compounds

Accidental Release Measures

Personal Precautions: Isolate area, evacuate unnecessary personnel, wear approved respirator, protective gloves, goggles, and full body covering
Environmental Precautions: Avoid release to environment, prevent spillage entering drains, watercourses, or soil
Methods for Clean-Up: Avoid creating dust, sweep or shovel up material using approved antistatic tools, dispose waste in accordance with local regulations; use vacuum systems with HEPA filters for fine particles
Decontamination: Wash spill site with water and detergent once cleanup is complete
Disposal of Contaminated Material: Bag for authorized waste disposal contractor

Handling and Storage

Safe Handling Precautions: Avoid breathing dust, avoid contact with skin, eyes, and clothing, always handle in chemical fume hood or well-ventilated area, ensure proper training before working with this product
Storage Conditions: Store in tightly closed original container, keep in cool, dry, and well ventilated area away from incompatible substances, limit exposure to direct light and moisture
Incompatibilities: Strong oxidizing agents, strong acids, strong bases
Hygiene Measures: Wash hands and face thoroughly after handling, do not eat or drink in workplace, remove contaminated clothing before leaving workspace

Exposure Controls and Personal Protection

Exposure Limits: No established occupational exposure limits; handle as for hazardous pharmaceutical chemicals
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits
Respiratory Protection: NIOSH approved respirator if dust formation takes place
Eye Protection: Chemical splash goggles or face shield
Skin Protection: Wear impervious gloves (nitrile or PVC), lab coat or full body suit
Environmental Exposure Controls: Prevent further leakage or spillage if safe to do so, do not let product enter drains

Physical and Chemical Properties

Appearance: Off-white to pale yellow powder
Odor: Mild, characteristic
Odor Threshold: Not determined
pH: Not available in supplied form, weakly acidic in solution
Melting Point/Freezing Point: Decomposes above 150°C
Boiling Point: Not applicable (decomposes)
Flash Point: Not determined
Evaporation Rate: Not applicable
Flammability: May form explosive dust-air mixtures
Vapor Pressure: Negligible at room temperature
Vapor Density: Not determined
Bulk Density: Approx. 0.3 - 0.5 g/cm³
Solubility: Slightly soluble in water, more soluble in methanol, ethanol, acetone
Partition Coefficient n-octanol/water: Not determined
Auto-Ignition Temperature: Not determined
Decomposition Temperature: >150°C
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under standard handling and storage at recommended temperatures and conditions
Possibility of Hazardous Reactions: May react with strong acids, bases, oxidizing agents
Conditions to Avoid: Moisture, high temperature, sources of ignition, dust formation
Incompatible Materials: Strong oxidizing agents, acids, alkalis
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, possible tar by-products

Toxicological Information

Acute Toxicity: Data limited; animal studies indicate moderate toxicity by ingestion and inhalation
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Symptoms of Exposure: May lead to skin redness, eye watering, respiratory discomfort, allergic symptoms or skin sensitization
Chronic Effects: Risk of asthma or dermatitis following repeated exposure; possible immunosensitization
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA
Mutagenicity: Not enough information, treat as potential hazard
Reproductive Toxicity: No targeted reproductive effects reported
Medical Conditions Aggravated: Asthma, skin diseases, allergies

Ecological Information

Aquatic Toxicity: Limited studies suggest harmful to aquatic organisms, with potential long-term adverse effects
Persistence and Degradability: Not readily biodegradable, remains in environment if not treated
Bioaccumulation Potential: Low to moderate, unlikely to concentrate in higher organisms
Mobility in Soil: Low; remains mostly adsorbed to soil or sediment
Other Adverse Effects: May contribute to antibiotic resistance in water systems if not controlled

Disposal Considerations

Waste Management: Dispose as hazardous waste according to national, state, and local regulations
Methods of Disposal: Incineration preferred, use licensed waste disposal contractor
Precautions for Disposal: Do not allow to enter drains, water courses, soil
Packaging Disposal: Use triple-rinsing or designated disposal containers, never reuse contaminated packaging for any purpose

Transport Information

UN Number: Not regulated under most transport codes
Proper Shipping Name: Kitasamycin Tartrate Base
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not assigned
Special Precautions for User: Avoid spillage and dust formation during loading and unloading
Environmental Hazards: Not marine pollutant but precautions required to prevent accidental release

Regulatory Information

Regulatory Status: Not listed as controlled substance; subject to chemical safety assessment
Industry Specific Regulations: Handle according to pharmaceutical and veterinary health and safety regulations, OSHA and local workplace rules
Hazard Communication: Product label must contain hazard warning, safe handling advice, emergency response information
Inventory Listings: May be listed under national chemical inventory. Confirm with local chemical authorities.
Worker Protection: Training in chemical handling and personal protective equipment mandated by workplace rules