Product Name: Iron(II) gluconate hydrate
Synonyms: Ferrous gluconate, Gluconic acid iron(2+) salt, hydrate
Chemical Formula: C12H22FeO14•xH2O
CAS Number: 299-29-6
Recommended Uses: Food fortification, nutritional supplement, pharmaceutical ingredient, research laboratories
Supplier Details: Name, address, phone, and emergency contact of the supplier or manufacturer
Emergency Contact: Local poison control center, fire department, or manufacturer’s emergency number
Classification: Not classified as hazardous according to GHS (Globally Harmonized System)
Signal Word: Not applicable
Hazard Statements: Dust may irritate eyes, nose, throat, or skin
Pictograms: None required
Precautionary Statements: Avoid generating dust, wear suitable protection, practice good workplace hygiene
Other Hazards: May cause mild gastrointestinal discomfort if ingested in large quantities; may produce iron overload with chronic or excessive exposure
Routes of Exposure: Oral, inhalation, dermal, eye contact
Chronic Effects: Prolonged high-level ingestion may lead to iron overload; no evidence of carcinogenic, mutagenic, or reproductive effects at occupational exposure levels
Chemical Name: Iron(II) gluconate hydrate
Common Name: Ferrous gluconate
CAS Number: 299-29-6
Content: >97% (weight/weight basis)
Impurities: Trace amounts of related gluconate salts, water (hydrates), possible residual starting materials
Molecular Weight: 448.14 (anhydrous), varies with hydration
Inhalation: Move exposed individual to fresh air; monitor for breathing difficulties; seek medical attention for symptoms
Skin Contact: Remove any contaminated clothing; wash skin thoroughly with soap and water; seek medical attention for persistent irritation
Eye Contact: Rinse cautiously with clean, lukewarm water for several minutes; remove contact lenses if present and easy to do; get medical attention if irritation persists
Ingestion: Rinse mouth and drink water to dilute; do not induce vomiting; seek immediate medical attention for large exposures or if vomiting, drowsiness, or pain occurs
Most Important Symptoms: Mild skin, eye, respiratory irritation; large oral intake may result in iron toxicity symptoms (abdominal pain, vomiting, diarrhea)
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Special Hazards from Fire: May generate carbon oxides, iron oxides, irritating fumes; no unusual fire or explosion risk
Advice for Firefighters: Wear self-contained breathing apparatus and protective gear; prevent runoff contamination; approach from upwind
Thermal Decomposition Products: Carbon monoxide, carbon dioxide, iron oxides, other organic decomposition products
Personal Precautions: Use dust mask, gloves, eye protection; avoid dust formation; ventilate area
Environmental Precautions: Avoid release to waterways and drains
Containment: For small spills, sweep carefully to avoid dust; for larger amounts, use vacuum with HEPA filter
Cleanup Methods: Collect product in suitable container for disposal or reuse; wash spill area with water; prevent spills from entering environment
Decontamination: Clean non-recoverable product with detergent and water
Handling: Work in well-ventilated area; wear dust protection; avoid breathing dust or contact with eyes/skin; practice good hygiene such as hand washing after handling
Storage: Keep container tightly closed in dry, cool, well-ventilated place; protect from moisture, direct sunlight, incompatible materials (strong oxidizers, acids); keep away from food and beverages
Incompatible Materials: Strong oxidizing agents, strong acids
Exposure Limits: No established occupational exposure limits for iron(II) gluconate hydrate; general nuisance dust limits apply (e.g., OSHA PEL for particulates not otherwise regulated: 15 mg/m³ total dust, 5 mg/m³ respirable fraction)
Engineering Controls: Local exhaust ventilation, general dilution ventilation
Personal Protection:
Appearance: Yellowish to gray-green powder or granules
Odor: Practically odorless
Odor Threshold: Not determined
pH (1% solution): 4.5–5.5
Melting Point: Decomposes before melting
Boiling Point: Not applicable
Flash Point: Not flammable
Flammability: Not considered flammable
Autoignition Temperature: Not determined
Vapor Pressure: Negligible
Vapor Density: Not applicable
Evaporation Rate: Not applicable
Solubility: Soluble in water, insoluble in most organic solvents
Partition Coefficient (n-octanol/water): Not available
Decomposition Temperature: > 200°C
Bulk Density: Varies with granule size, typically 0.6–1.0 g/cm³
Molecular Weight: 448.14 (anhydrous)
Chemical Stability: Stable under normal ambient storage and handling conditions
Reactivity: May react with strong oxidizers or acids
Hazardous Reactions: No hazardous polymerization
Conditions to Avoid: Excessive heat, moisture, strong oxidizing environments
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition Products: May produce carbon oxides, iron oxides under severe heating or combustion
Acute Toxicity: Low acute toxicity by oral, inhalation, or dermal routes; human LD50 oral estimated > 2000 mg/kg
Inhalation: Dust may cause mild respiratory tract irritation
Skin: May cause mild irritation with prolonged or repeated contact
Eyes: May cause mild transient irritation
Ingestion: Large doses may result in symptoms of iron toxicity (nausea, vomiting, diarrhea, abdominal pain)
Chronic Effects: Chronic overexposure may cause iron overload and associated health problems
Sensitization: No evidence for skin sensitization
Carcinogenicity: Not listed as a carcinogen by IARC, ACGIH, NTP, or OSHA
Mutagenicity / Reproductive Effects: No relevant data indicating genotoxic or reproductive risks
Environmental Impact: Not expected to pose significant risk at low concentrations
Ecotoxicity: No data indicating significant hazard to aquatic organisms at expected use levels
Persistence and Degradability: Expected to degrade by natural processes; iron components can persist but do not bioaccumulate
Mobility in Soil: Water-soluble fraction may migrate in soil and water
Bioaccumulation Potential: Not expected
Other Adverse Effects: Large quantities may cause localized environmental effects due to iron enrichment
Waste Disposal: Dispose of small quantities as regular waste if allowed by local regulations; larger amounts or contaminated material should follow facility protocols and legal requirements
Container Disposal: Rinse thoroughly before recycling or disposal; follow regional and national regulations
Precautions: Prevent spillage into drains, soil, or water sources to avoid iron enrichment of environment
UN Number: Not regulated
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions: Minimize dust generation; keep container sealed; transport in labelled, robust packaging; observe general precautions for chemical shipment
Safety, Health, and Environmental Regulations: Not listed as hazardous under OSHA Hazard Communication Standard; regulated as food additive in many countries; TSCA listed in the United States
Labelling Requirements: No major label elements required for non-industrial use; recommendations for precautionary statements
Restrictions: Check local, national, and international guidelines for specific restrictions or permissions regarding use and disposal
Chemical Inventory Status: Present on TSCA, EINECS, DSL, AICS, ENCS, and other relevant chemical inventories where registered
Other Regulations: Product as an ingredient in food, nutraceutical, and pharmaceutical preparations should comply with US FDA, EU food safety, or other agencies as applicable
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