Product Name: (S)-1-amino-3-chloro-2-propanol hydrochloride
Synonyms: (S)-1-amino-3-chloro-2-propanol HCl
CAS Number: 104706-47-0
Recommended Uses: Laboratory research, chemical synthesis, intermediate for pharmaceuticals
Supplier: Major fine chemical manufacturers, research distributors
Emergency Contact: Refer to local supplier emergency hotline for 24-hour response
Classification: Acute toxicity (oral, dermal), Skin and Eye irritation, Environmental hazard
Pictograms: Exclamation mark, Health hazard, Environmental hazard
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and serious eye irritation, may cause respiratory irritation, hazardous to aquatic life with long-lasting effects
Precautionary Statements: Avoid breathing dust and vapors, wear protective clothing and eye protection, wash thoroughly after handling, avoid release to the environment
Other Hazards: May cause central nervous system effects if absorbed, dust generation increases exposure risk
Chemical Identity: (S)-1-amino-3-chloro-2-propanol hydrochloride
Molecular Formula: C3H9Cl2NO
Molecular Weight: 146.02 g/mol
Concentration: 97-100% active ingredient
Impurities: Traces of related amino alcohols, minor residual solvents possible
Ingredient List: Main component only, no stabilizers or additives listed
Inhalation: Move person to fresh air, keep at rest, monitor breathing, seek immediate medical attention if symptoms develop
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water and mild soap, obtain medical advice if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue flushing, seek urgent medical attention
Ingestion: Do not induce vomiting, rinse mouth with water, seek immediate medical advice, provide information about the product to responsive health professionals
Advice to Physician: Treat symptoms, monitor for delayed effects particularly neurotoxicity and respiratory irritation; provide specific therapy for chemical toxicity
Suitable Extinguishing Media: Carbon dioxide, dry powder, foam, or water spray as appropriate for surrounding fire; avoid high-pressure water streams
Fire Hazards: Decomposition can release toxic and corrosive fumes of HCl, nitrogen oxides, and chlorine
Personal Protection: Firefighters should wear self-contained breathing apparatus and full protective gear, use water spray to cool containers
Combustion Products: Hydrogen chloride, carbon monoxide, carbon dioxide, nitrogen oxides, possible traces of chloroorganic gases
Explosion Data: Not considered highly explosive, but dust can create static accumulation hazard in certain settings
Personal Precautions: Avoid inhaling dust or vapors, ventilate area, evacuate unnecessary personnel, use personal protective equipment including respirator
Environmental Precautions: Prevent entry into drains, sewers, or waterways; contain spill with inert absorbents such as sand or vermiculite
Cleanup Methods: Absorb spill with dry material, collect in suitable sealed containers for disposal, clean area with detergent and water, avoid generating airborne dust
Disposal: Transport waste in accordance with regulatory guidelines, label appropriately, ensure spill residues are removed to prevent future exposure
Handling: Minimize exposure by working in well-ventilated area, avoid inhalation of dust, use local exhaust if available, avoid direct contact with skin and eyes, prevent static buildup by grounding containers and handling equipment
Storage: Store in tightly closed containers, keep cool and dry, segregate from incompatible substances such as strong oxidizers, acids, and bases, avoid sunlight and moisture, ensure containers are labeled clearly
Special Considerations: Protect product from physical damage, inspect packaging regularly for leaks or deterioration, maintain access control to storage areas
Occupational Exposure Limits: No established occupational exposure limits for this compound, use controls appropriate for similar amino-alcohols
Engineering Controls: Use chemical fume hoods, maintain mechanical exhaust, implement local ventilation where dust/vapors may be generated
Personal Protection: Suitable lab gloves (nitrile recommended), chemical splash goggles, lab coats, suitable respirator if ventilation is insufficient, avoid skin exposure, do not eat or drink in work area
Hygiene Measures: Wash hands before breaks and after handling, do not reuse contaminated PPE, dispose PPE per lab protocols
Appearance: White to off-white crystalline powder or solid
Odor: Faint amine odor
pH (aqueous solution): 3-4
Melting Point: 172-178°C
Boiling Point: Decomposes prior to boiling
Flash Point: Not applicable (solid, high melting)
Solubility: Soluble in water, partially soluble in polar organic solvents
Density: Approximately 1.19 g/cm³
Vapor Pressure: Negligible at 20°C
Partition Coefficient (log Kow): Estimated low, product prefers aqueous phase
Stability under Light and Air: Stable if kept sealed and dry
Formulation State: Used as supplied; not typically blended for application
Reactivity: Product stable under recommended storage conditions, may react with strong acids, bases, and oxidizing agents
Chemical Stability: Stable under ordinary conditions, decomposes at elevated temperature, damp, or acidic environment
Possibility of Hazardous Reactions: Risk of hazardous gases if mixed with reactive chemicals
Hazardous Decomposition Products: Hydrogen chloride gas, ammonia, carbon oxides, chloro-organic byproducts
Conditions to Avoid: Moisture, excessive heat, high humidity, open flames, incompatible materials
Incompatible Materials: Strong oxidizers, concentrated mineral acids, strong bases, reactive metals
Acute Toxicity: Oral LD50 (rat) estimated at 200-500 mg/kg, considered toxic if swallowed
Skin Corrosion/Irritation: May cause irritation, especially on prolonged or repeated skin contact
Serious Eye Damage/Irritation: Causes severe irritation, potential for corneal damage
Respiratory Sensitization: Inhalation of powders/dust may irritate respiratory tract and cause coughing or shortness of breath
Chronic Effects: Prolonged or repeated exposure may impact central nervous system, possible kidney and liver stress
Genotoxicity: No data for this compound, similar related molecules show no direct mutagenic potential
Carcinogenicity: No components listed by IARC, NTP, or OSHA as carcinogenic
Other Effects: Users with allergies to amine groups or vulnerable respiratory systems may be more sensitive
Acute Aquatic Toxicity: Harmful to aquatic organisms at low concentrations, can cause long-term adverse effects
Persistence & Degradability: Degrades slowly in environment, hydrolysis possible in acidic/basic media
Bioaccumulation Potential: Not expected to bioaccumulate significantly due to hydrophilicity
Mobility in Soil: Mobile in water, readily migrates if released to soil
Other Ecological Effects: Possible toxic effects on bacteria and lower aquatic organisms, may disrupt local microbial populations in wastewater streams
Waste Disposal: Do not discharge to the environment, collect all waste in labeled containers, treat as hazardous chemical waste
Disposal Methods: Send to licensed chemical disposal contractor, practice incineration in controlled facilities, comply strictly with regional and national disposal regulations
Contaminated Packaging: Rinse containers thoroughly, treat as hazardous waste, dispose based on local rules for dangerous containers
Special Precautions: Never dispose through drains or regular municipal waste, minimize unnecessary handling of waste
UN Number: Not classified under UN hazardous transport codes for most jurisdictions
Transport Name: Chemical, non-regulated for transport unless packed with other dangerous goods
Class: Not applicable for ground or air
Packing Group: Not assigned
Marine Pollutant: Yes, avoid release near waterways
Transport Notes: Use strong secondary packaging to prevent spills, label all shipments with product and hazard information, keep documentation available during transit
Labelling: Follow GHS labelling with appropriate pictograms and hazard statements
Section 313 (SARA Title III): Not listed
TSCA: Complies with inventory requirements
REACH: Not registered at typical import volumes; handle as per REACH safety measures for intermediates
Workplace Regulations: OSHA Hazard Communications applies, employer required to provide hazard training
Other Local Regulations: Comply with all country-specific handling, labeling, and environmental release laws; update internal protocols as rules evolve
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