Chemical Name: ETHYL (R)-3-NIPECOTATE L-TARTRATE
Chemical Formula: C12H19NO8
Synonyms: Ethyl (R)-3-piperidinecarboxylate tartrate, Ethyl 3-nipecotate tartrate
CAS Number: 167228-49-5
Recommended Use: Used as an intermediate in organic synthesis and pharmaceutical research
Supplier Information: Contact details, including address and emergency phone number of manufacturer or distributor, should be available on the product label and shipping documents
Product Code: Detailed as per supplier system for traceability
Emergency Contact: Company emergency line, Poison Control Centers, and local emergency numbers provide point-of-contact in urgent cases
Classification: Classified as an irritant under local and international chemical safety regulations
Label Elements: Signal word: Warning; Hazard pictograms displaying skin and eye irritation
Hazard Statements: Causes skin and eye irritation, may cause respiratory tract irritation
Precautionary Statements: Wear protective gloves, clothing, and eye protection; wash hands thoroughly after handling; avoid inhaling dust or fumes
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Effects of Overexposure: Irritation, redness, burning sensation, possible headache or nausea
Other Hazards: No known carcinogenic, mutagenic, or reproductive toxicity reported based on available data; dust can present a slip hazard
Main Ingredient: ETHYL (R)-3-NIPECOTATE L-TARTRATE: approximately 95-100% by weight
Impurities: Trace levels of unreacted precursor acids, esters, and possible salts (reported as <1%)
Stabilizers or Additives: None expected in standard formulations; verify with supplier for batch-specific variations
Inhalation: Remove to fresh air promptly; seek medical attention if symptoms like coughing, shortness of breath, or dizziness persist
Skin Contact: Rinse exposed skin with plenty of water and mild soap for at least 15 minutes; remove contaminated clothing and launder before reuse; seek care if irritation continues
Eye Contact: Rinse eyes gently with water, lifting eyelids as necessary, for a minimum of 15 minutes; remove any contact lenses and seek urgent medical attention if symptoms persist
Ingestion: Rinse mouth with water thoroughly; do not induce vomiting unless directed by a medical professional; seek immediate medical attention for persistent symptoms such as abdominal pain, vomiting, or dizziness
Note for Healthcare Providers: Treat symptomatically; monitor for respiratory complications or allergic reactions in sensitive individuals
Suitable Extinguishing Media: Use CO2, dry chemical, or foam for small fires; water spray for larger fires involving surrounding materials
Unsuitable Media: Avoid direct water stream to prevent chemical runoff
Specific Hazards: Combustion may generate toxic fumes including nitrogen oxides and carbon monoxide
Protective Equipment for Firefighters: Full protective gear, self-contained breathing apparatus (SCBA)
Special Procedures: Cool exposed containers with water; ventilate area after fire subsides; avoid inhaling fumes
Explosion Data: No specific risk of explosion based on structure and standard storage
Personal Precautions: Evacuate area and wear appropriate protective equipment, including gloves, goggles, and approved respirator if airborne dust is present
Environmental Precautions: Prevent entry into sewers, waterways, or soil; inform local authorities of large spills
Clean-Up Methods: Sweep up solid material using non-sparking tools and collect in suitable, labeled containers for disposal; ventilate area and wash spill site after material pickup
Decontamination: Wash contaminated surfaces with soap and water, ensuring complete removal before area is returned to normal use
Handling: Use in well-ventilated areas with appropriate local exhaust or fume hood; avoid contact with skin, eyes, and clothing; use compatible equipment and clean all tools before and after use
Storage Conditions: Store in tightly closed containers away from direct sunlight, moisture, and sources of heat or ignition; maintain ambient temperature and avoid freezing or excessive heat fluctuations
Incompatible Materials: Strong oxidizers, strong bases, and strong acids may cause hazardous reactions
Specific Requirements: Use secondary containment for bulk storage; label clearly for hazard communication; segregate from food and feed
Occupational Exposure Limits: No specific occupational exposure limit has been established; follow general dust and chemical hygiene standards
Engineering Controls: Use chemical fume hood or local exhaust ventilation; implement spill and splash containment in work areas
Personal Protective Equipment: Impervious gloves, safety goggles, long lab coats or coveralls; use respirators compliant with national standards if dust or fumes are present
Hygiene Measures: Wash hands before eating, drinking, or using restroom; avoid eating or drinking in work areas; shower and launder clothing after handling
Appearance: White to off-white crystalline solid
Odor: Mild, characteristic
Melting Point: 125-130°C (reported range)
Boiling Point: Not easily distilled before decomposing
Solubility: Soluble in water and alcohols; slightly soluble in organic solvents like ether
Specific Gravity: Approximately 1.3 (estimated)
pH (1% solution): Slightly acidic, typically 4-5
Partition Coefficient: Not available
Vapor Pressure: Negligible at room temperature
Evaporation Rate: Not applicable
Flash Point: Not applicable (solid material)
Decomposition Temperature: Decomposes above 150°C
Other Properties: Stable under standard conditions but sensitive to prolonged exposure to air and moisture
Chemical Stability: Stable under normal temperatures and pressures; store in tightly closed container
Possible Hazardous Reactions: No hazardous polymerization expected under recommended storage and use conditions
Conditions to Avoid: Exposure to extreme moisture, heat, or open flames; avoid strong oxidizing or reducing agents
Incompatible Materials: Contact with acids, bases, or strong oxidizers can cause degradation or hazardous fumes
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, organic acids, and possibly unidentified toxic compounds
Other Notes: Store away from incompatible chemicals and observe all standard lab safety protocols
Acute Toxicity: Limited toxicity data on chemical; related compounds cause mild to moderate irritation on contact or ingestion
Routes of Exposure: Inhalation of dust, skin and eye contact, accidental ingestion
Symptoms: Redness, irritation, coughing, nausea, headache; severe exposure can cause gastrointestinal upset
Chronic Effects: No chronic toxicity reported or characterized specifically for this compound; related substances occasionally reported to trigger allergic responses after repeated exposure
Carcinogenicity: No evidence of carcinogenicity or mutagenicity based on available scientific literature
Target Organs: Skin, eyes, respiratory tract (with high exposure)
Other Information: Safety profile similar to other tartrate esters and nipecotate derivatives; always use good industrial hygiene practices
Ecotoxicity: No specific test data available; structurally similar compounds reportedly low in bioaccumulation and moderately degradable
Persistence and Degradability: Expected to degrade slowly in soil and water; hydrolyzes to organic acids and alcohols
Bioaccumulation Potential: Low; expected to break down into smaller, less bioactive molecules in nature
Mobility in Soil: Moderate water solubility may allow movement through upper soil layers, but rapid breakdown minimizes long-term risks
Other Adverse Effects: Avoid large uncontrolled releases to waterways or soil; proper disposal and spill control limit environmental impact
Waste Treatment Methods: Collect residues and contaminated absorbents in clearly labeled, corrosion-resistant containers; dispose through an approved chemical waste facility
Contaminated Packaging: Rinse containers if possible, or treat as hazardous waste if residues remain
Disposal Precautions: Do not release to sewer, ground, or waterways; follow local, regional, and national hazardous waste regulations
Recycling or Reclamation: Not typically feasible for laboratory or small-scale quantities; check with local waste services for possible options
UN Number: Not classified as a dangerous good for transport under United Nations or major international guidelines
Transport Hazard Class: Not subject to hazardous substance shipping rules in most jurisdictions
Packing Group: Not applicable
Shipping Procedures: Ship in tightly closed, clearly labeled packaging; protect containers from damage and keep upright
Additional Transport Notes: Keep away from food and feedstuffs during shipping; provide documents indicating chemical identification and hazard class (if required)
Labelling Requirements: Conform to standards set out by OSHA Hazard Communication Standard (29 CFR 1910.1200), EU CLP Regulation, and other local guidelines
Inventory Status: Check regulatory status against chemical inventories like TSCA (US), REACH (EU), and DSL (Canada)
Reporting Obligations: Ensure compliance with workplace exposure notifications and chemical release reporting as applicable by law
Other Local, State, and National Regulations: Refer to regional occupational health, waste disposal, and transportation safety requirements for updates or changes in regulatory control
Restrictions: Follow any restricted or controlled uses based on product registration and application, especially for pharmaceutical or agricultural research
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