Product Name: Ethyl Acetoacetate Propylene Glycol Ketal
Chemical Family: Ketal
Molecular Formula: C10H18O4
Molecular Weight: 202.25 g/mol
CAS Number: 67480-73-9
Synonyms: EAA-PG-Ketal
Uses: Solvent, flavor and fragrance intermediate, chemical synthesis
Supplier: Manufacturer or distributor identified by label
Emergency Phone: Refer to label on container for regional emergency hotline
GHS Classification: Flammable liquid (Category 3), Eye irritation (Category 2A), Skin irritation (Category 2)
Signal Word: Warning
Hazard Statements: May cause skin irritation. Causes serious eye irritation. Flammable liquid and vapor. May be harmful if swallowed or inhaled.
Pictograms: Flame, Exclamation mark
Precautionary Statements: Keep away from open flames, hot surfaces, and sources of ignition. Avoid contact with eyes and skin. Use only in a well-ventilated area.
Target Organs: Eye, skin, respiratory system
Component: Ethyl Acetoacetate Propylene Glycol Ketal
Concentration: 95–100%
Impurities: Ethyl acetoacetate (<2%), propylene glycol (<2%)
Other Components: No additives, stabilizers, or non-reactive carriers reported
Inhalation: Move to fresh air. If breathing difficulty occurs, seek immediate medical attention. Administer oxygen if breathing is difficult. Remove contaminated clothing and loosen tight garments around the neck.
Skin Contact: Remove contaminated clothing. Rinse skin with plenty of water for at least 15 minutes. Wash with mild soap. If irritation persists, seek medical advice.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present. Continue rinsing and consult a physician promptly.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting without medical supervision. Seek immediate medical attention.
Suitable Extinguishing Media: Use foam, carbon dioxide, dry chemical, or water spray. Avoid heavy water stream to prevent the spread of burning liquid.
Unsuitable Media: Direct water jet can spread the material
Fire Hazards: Product forms flammable vapors above flash point. Vapors may travel long distances and ignite explosively.
Hazardous Combustion Products: Carbon oxides (CO, CO2), irritating organic vapors
Protective Equipment: Firefighters should wear full protective gear, including self-contained breathing apparatus (SCBA).
Personal Precautions: Evacuate area and ensure adequate ventilation. Wear gloves, goggles, and suitable protective clothing. Remove all ignition sources.
Environmental Precautions: Prevent entry into sewers, drains, or waterways.
Cleanup Methods: Absorb spill with inert material such as dry sand or earth. Collect and place in suitable containers for disposal. Wash spill site after material pick-up is complete.
Reporting: Notify regulatory authorities as required.
Handling: Use only in well-ventilated areas. Avoid breathing vapors or mist. Do not get in eyes, on skin, or on clothing. Use explosion-proof equipment.
Storage: Store in a tightly closed container. Keep in a cool, dry, well-ventilated area away from direct sunlight and incompatible materials. Store away from heat sources, oxidizers, acids, and bases. Ground and bond containers during transfer.
Container Materials: Use steel or high-density polyethylene containers resistant to ketals.
Occupational Exposure Limits: No official threshold limit value established for this compound; consider comparable ketal or glycol ethers (TLV: 50 ppm, as analogy, consult local regulations)
Engineering Controls: Provide local exhaust ventilation to minimize vapor exposure.
Personal Protective Equipment (PPE): Chemical splash goggles, protective gloves (nitrile or neoprene), lab coat or apron, closed-toe shoes. Use a respirator with organic vapor cartridge when ventilation cannot eliminate exposure.
Hygiene Measures: Wash thoroughly after handling. Do not eat, drink, or smoke while using this product.
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild, fruity, ester-like
Odor Threshold: Not tested
pH: Not applicable
Melting Point/Freezing Point: < -40°C
Boiling Point/Range: 210–220°C
Flash Point: 66°C (Closed cup)
Evaporation Rate: Slower than ether
Flammability (solid, gas): Not applicable
Upper/Lower Flammability or Explosive Limits: Lower: 1.2%; Upper: 8.5%
Vapor Pressure: 0.3 mmHg at 20°C
Vapor Density: Heavier than air (air = 1)
Relative Density: 1.06–1.10 (water = 1)
Solubility (Water): Slightly soluble
Partition Coefficient (n-octanol/water): log Kow ~1.8
Auto-ignition Temperature: 280°C
Decomposition Temperature: Above 220°C
Viscosity: 6–9 mPa·s at 25°C
Chemical Stability: Stable under recommended storage conditions and at room temperature.
Polymerization: Does not polymerize.
Reactivity: Reacts with strong acids, bases, and oxidizing agents.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, and other toxic vapors when heated to decomposition.
Acute Toxicity: LD50 (oral, rat): 1800 mg/kg estimate; LD50 (dermal, rabbit): 4200 mg/kg estimate
Skin Irritation: Moderate to severe irritation on prolonged exposure
Eye Irritation: Severe, can cause redness, pain, and temporary damage to corneal tissue
Inhalation: May produce dizziness, headache, respiratory irritation at higher concentrations
Chronic Toxicity: Prolonged exposure may affect liver and kidneys
Mutagenicity: No data available
Reproductive Effects: No data available
Aquatic Toxicity: LC50 (fish, 96h): 130 mg/L; EC50 (Daphnia, 48h): 70 mg/L
Degradability: Expected to biodegrade slowly under aerobic conditions
Bioaccumulation: Potential for low to moderate accumulation based on log Kow
Mobility in Soil: Low to moderate mobility predicted; product can leach to groundwater if uncontrolled spills occur
Other Adverse Effects: High concentrations in watercourses may cause harm to aquatic organisms.
Waste Treatment: Incinerate in approved facility or dispose of according to local, state, national, and international regulations
Container Disposal: Triple rinse drums and containers before disposal. Dispose of rinsates as hazardous waste.
Special Notes: Do not pour into drains or water courses.
UN Number: UN1987
Proper Shipping Name: Alcohols, n.o.s. (contains Ethyl Acetoacetate Propylene Glycol Ketal)
Hazard Class: 3 (Flammable liquid)
Packing Group: III
Labels: Flammable Liquid
Special Precautions: Transport with secure closures and upright. Avoid rough handling. Follow local regulations for flammable substances.
TSCA: Listed
REACH: Registration required for manufacture or import into European Economic Area
OSHA Hazards: Flammable liquid, irritant
SARA 313: Not listed
California Proposition 65: Not listed
Labeling Requirements: GHS-compliant labeling including hazard and precautionary pictograms/statements
Other Regulations: Subject to local and international transport and workplace safety standards
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