Product Name: (-)-Epinephrine-(+)-Hydrogentartrate
Synonyms: Adrenaline hydrogentartrate, L-Epinephrine hydrogen tartrate
CAS Number: 51-42-3
Molecular Formula: C13H19NO9
Manufacturer: Major pharmaceutical providers and chemical distributors
Intended Use: Pharmaceutical, research, laboratory reagents
Contact Information: Available on request from supplier
GHS Classification: Acute toxicity (oral) Category 4, eye irritation Category 2A, skin sensitization Category 1
Health Hazards: Shortness of breath, headache, increased heart rate, palpitations, anxiety, tremor
Environmental Hazards: May harm aquatic life in high concentrations
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes serious eye irritation, may cause allergic skin reactions, may cause chronic symptoms with long term exposure
Pictograms: Exclamation mark, health hazard symbol
Chemical Identity: (-)-Epinephrine-(+)-Hydrogentartrate
Common Name: Adrenaline hydrogentartrate
Concentration: 98-100%
Impurities: Trace mineral salts and residual solvents not exceeding regulated limits
Molecular Weight: 333.29 g/mol
Inhalation: Move to fresh air, rest, seek medical attention for difficulty breathing, monitor breathing closely
Skin Contact: Rinse with soap and water, remove contaminated clothing, seek help with persistent irritation
Eye Contact: Rinse eyes gently with water for 15 minutes, check for redness and pain, call a health professional if irritation continues
Ingestion: Rinse mouth, drink water if alert, do not induce vomiting, get immediate medical attention
Most Important Symptoms: Fast heartbeat, high blood pressure, sweating, tremors, dizziness, unclear vision, agitation
Protective Advice for Rescuers: Use gloves, avoid direct contact, keep airway open, wash thoroughly after assisting
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, foam
Unsuitable Extinguishing Media: Direct jet of water on powder
Hazards from Combustion: Emits toxic fumes of carbon oxides, nitrogen oxides
Firefighter Instructions: Wear self-contained breathing apparatus, use protective clothing, keep containers cool by spraying water
Specific Hazards: Product dust may form explosive mixture with air, closed containers can explode under extreme heat
Personal Precautions: Wear safety goggles, gloves, dust mask or respirator, keep unprotected people away
Environmental Precautions: Prevent spillage from entering sewage or natural waters, contain with barriers if possible
Cleanup Methods: Collect with non-sparking tools, sweep up into suitable container, ventilate area, wash spill site with soap solution after material pick-up
Disposal: Place in designated waste containers, follow chemical waste guidelines for site
Recommendations: Avoid dust generation, do not touch spilled material without protective equipment
Handling: Avoid inhalation, ingestion, contact with eyes and skin by using protective gear, work in well-ventilated areas, keep containers tightly closed when not in use
Hygiene: Always wash hands after use, avoid eating or drinking where chemical is handled
Storage: Store in a cool, dry location separate from incompatible substances such as strong oxidizers, acids, and bases, use light-resistant containers to avoid decomposition
Storage Conditions: Temperature below 8°C preferred for long-term stability, protected from moisture and direct sunlight
Special Considerations: Label containers clearly, restrict access to authorized individuals
Exposure Limits: Not established specifically for this compound, general pharmaceutical dust guidelines apply
Engineering Controls: Use fume hood or local exhaust ventilation in laboratories and production areas, monitor for airborne dust
Personal Protection: Appropriate laboratory gloves, safety goggles, lab coat, NIOSH-approved particulate respirator for powder handling
Environmental Controls: Prevent product from reaching drains and waterways, use wastewater treatment for contaminated effluents
Workplace Practices: Avoid skin contact, change gloves regularly, wash exposed skin promptly
Appearance: White to light beige crystalline powder
Odor: Odorless or very faint chemical odor
pH (1% solution): Approximately 3.0 - 4.5
Melting Point: 183°C with decomposition
Boiling Point: Not applicable (decomposes on heating)
Solubility: Freely soluble in water, slightly soluble in alcohol
Vapor Pressure: Negligible at room temperature
Density: ±1.5 g/cm³
Flash Point: Not flammable in solid form
Partition Coefficient (log Kow): -1.37
Decomposition Temperature: Above 180°C
Chemical Stability: Remains stable under recommended storage, moisture and light may cause degradation
Conditions to Avoid: High temperatures, excessive moisture, exposure to light, direct sunlight
Incompatible Materials: Strong oxidizing agents, strong acids or bases, heavy metals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Polymerization: No hazardous polymerization observed under normal conditions
Acute Toxicity: LD50 (oral, rat) approximately 10 mg/kg
Routes of Exposure: Skin contact, eye contact, ingestion, inhalation of powder or dust
Effects: Rapid pulse, high blood pressure, headache, nervousness, restlessness, tremors, palpitations, nausea, vomiting, sweating, sometimes life-threatening in sensitive individuals
Symptoms from Exposure: Allergic skin reactions, breathing difficulties, anxiety, visual disturbances, rarely kidney or liver effects
Chronic Exposure: Sensitization and sustained cardiovascular symptoms, possible changes in blood pressure control
Carcinogens: Not classified as carcinogenic by IARC, NTP, OSHA
Mutagenicity and Reproductive Toxicity: Evidence not conclusive; avoid chronic, high-level exposure especially in pregnancy
Aquatic Toxicity: May pose hazard at high concentrations to aquatic organisms
Persistence and Degradability: Rapidly biodegradable in aerobic environments, decomposition enhanced by sunlight and microbial action
Bioaccumulation Potential: Low due to high water solubility and rapid metabolism
Mobility in Soil: Moves easily in moist soil, not expected to persist in surface waters
Other Effects: Not expected to bioaccumulate or cause significant harm in typical laboratory or clinical disposal routes
Waste Treatment: Combine with water and treat in accordance with local, state, and federal environmental regulations
Disposal Methods: Large volumes sent to chemical incinerator after neutralization, laboratory quantities disposed via standard pharmaceutical waste systems
Container Disposal: Leave minimal residue, rinse with water, puncture and dispose of in accordance with regulatory guidance
Precautions: Do not allow product to reach soil, sewers, surface or ground water
Recommendations: Consult hazardous waste regulations and local authorities for legal disposal practices
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as dangerous goods by IATA, IMDG, or DOT
Hazard Class: None
Packing Group: None assigned
Special Precautions: Secure containers during transport, prevent spillage, avoid exposure to heat and moisture
Emergency Response: Not classified as hazardous, customary precautionary labeling and handling applies
OSHA Status: Not hazardous as defined by Hazard Communication Standard (29 CFR 1910.1200), but standard PPE should be used
TSCA Status: Listed or exempt
SARA/Title III: Not subject to reporting under SARA Title III Section 313
California Proposition 65: Not listed as causing cancer, birth defects, or other reproductive harm
EU Regulation: Not classified as hazardous under Regulation (EC) No 1272/2008
WHMIS Classification: Not controlled under Canadian regulations, observe general laboratory safety practices
Other Information: Users required to comply with all relevant national and local regulations regarding handling and disposal
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