Product Name: (?)-Epinephrine (+) Bitartrate Salt
Chemical Synonyms: Adrenaline bitartrate, Epinephrine hydrogen tartrate
CAS Number: 51-42-3
Recommended Use: Pharmaceutical manufacturing, laboratory research
Supplier: Major pharmaceutical suppliers and chemical distributors
Emergency Contact: Local poison control center or physician
GHS Classification: Acute toxicity (oral, Category 4), Eye irritation (Category 2A), Skin sensitization (Category 1)
Hazard Statement: Harmful if swallowed, causes serious eye irritation, may cause an allergic skin reaction
Signal Word: Warning
Pictograms: Exclamation mark, health hazard
Precautionary Statement: Avoid breathing dust, wash skin thoroughly after handling, wear eye and face protection, use gloves
Chemical Name: (?)-Epinephrine (+) bitartrate
Concentration: >98% pure
Formula: C13H19NO9
Relevant Impurities: Trace amounts of parent epinephrine and tartrate derivatives
Inhalation: Move person to fresh air, keep at rest, seek medical attention if symptoms persist
Skin Contact: Rinse skin with plenty of water, remove contaminated clothing, seek medical advice for persistent irritation
Eye Contact: Rinse cautiously with water for multiple minutes, remove contact lenses, continue rinsing, consult eye specialist if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical help
General Advice: Always offer medical MSDS to rescue personnel
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Specific Hazards: Emits toxic fumes including oxides of carbon and nitrogen under fire conditions
Protective Equipment: Full firefighting gear, self-contained breathing apparatus
Further Information: Avoid inhalation of combustion products, stay upwind
Personal Precautions: Use personal protective equipment, avoid dust formation
Environmental Precautions: Prevent spillage from entering drains and watercourses
Cleanup Methods: Pick up and arrange disposal without creating dust, sweep up and keep in suitable, closed containers for disposal
Decontamination Procedures: Wash spill site with water and detergent after material pickup
Precautions for Safe Handling: Avoid ingestion and inhalation, avoid contact with skin and eyes, use only in ventilated areas
Storage Requirements: Keep container tightly closed, store in a cool, dry place, protect from light, keep away from incompatible materials like strong bases and oxidizers
Specific Use: Restricted to laboratory and pharmaceutical environments only
Engineering Controls: Ensure adequate ventilation, use fume hoods, eye wash stations, and safety showers
Personal Protective Equipment: Protective gloves (nitrile recommended), chemical-resistant goggles, lab coat or apron, dust mask if powder is present
Respiratory Protection: Use approved respirators if exposure limits are exceeded or irritation is experienced
Hygiene Measures: Wash hands before breaks and at end of work, do not eat or drink near the area
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: 108–113°C
Boiling Point: Decomposes before boiling
Solubility: Readily soluble in water
pH (1% solution): Approx. 3.0–4.5
Partition Coefficient: Not established
Vapor Pressure: Negligible
Stability: Sensitive to air and light
Chemical Stability: Stable under recommended storage conditions
Reactivity: May react with strong oxidizers and bases
Hazardous Decomposition Products: Produces carbon oxides, nitrogen oxides, irritating phenolic vapors on burning
Polymerization: Does not occur under normal handling
Conditions to Avoid: Exposure to heat, moisture, light, and incompatible agents
Acute Toxicity: Oral LD50 (rat): 10–30 mg/kg (estimated)
Routes of Exposure: Ingestion, inhalation, skin, and eye contact
Symptoms: Headache, nausea, dizziness, elevated blood pressure, rapid heartbeat, possible allergic reaction or skin sensitization on repeated or prolonged contact
Carcinogenicity: No evidence of carcinogenic effects in animal studies
Genotoxicity: Not reported
Long-Term Effects: Prolonged exposure may impact liver or cardiovascular health
Ecotoxicity: Harmful to aquatic life with long-lasting effects
Persistence and Degradability: Degrades slowly in natural environments, especially under low-light conditions
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: Moderately mobile, especially in moist soils
Other Adverse Effects: Not identified
Disposal Methods: Dispose as hazardous pharmaceutical waste, follow local, regional, and national regulations
Container Disposal: Decontaminate triple-rinse before discarding solid waste containers
Precautions for Disposal: Avoid environmental release, use licensed disposal contractor
Special Instructions: Incineration at approved facility recommended for bulk material
UN Number: 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (epinephrine bitartrate)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Keep dry during transport, ensure containers are securely sealed and labeled
TSCA Status: Listed
EU Regulations: Classified and labeled according to CLP Regulation (EC) No 1272/2008
OSHA Hazards: Irritant, sensitizer
WHMIS Classification: D1B (Toxic material causing immediate and serious toxic effects)
REACH Compliance: Meets criteria for hazardous substances under REACH
Other Regulations: Subject to local, state, and national health and safety rules due to toxicity and pharmaceutical status
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