Product Name: Epinephrine Acid Tartrate
Synonyms: Adrenaline Tartrate, Epinephrine Hydrogen Tartrate
Chemical Formula: C9H13NO3 · C4H6O6
CAS Number: 51-42-3
Recommended Use: Pharmaceutical ingredient, research chemical
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GHS Classification: Acute Toxicity (Oral), Category 4; Acute Toxicity (Dermal), Category 3; Serious Eye Damage/Eye Irritation, Category 2
Signal Word: Danger
Hazard Statements: Harmful if swallowed. Toxic in contact with skin. Causes serious eye irritation.
Pictograms: Skull and crossbones, Exclamation mark
Precautionary Statements: Avoid contact with skin and eyes. Do not breathe dust. Wash hands thoroughly after handling. Wear protective gloves, protective clothing, and eye protection.
Chemical Name: Epinephrine Acid Tartrate
Common Name: Epinephrine Tartrate
CAS Number: 51-42-3
Percentage: ≥98% by weight
Impurities: Trace residual solvents below regulatory thresholds
Eye Contact: Rinse cautiously with water for at least 15 minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek immediate medical help.
Skin Contact: Take off contaminated clothing and wash skin with plenty of water. Medical attention may be required depending on extent of exposure.
Inhalation: Move to fresh air. Seek medical attention if symptoms develop or if exposed in large amounts.
Ingestion: Rinse mouth. Do not induce vomiting. Call poison control center or a doctor immediately.
Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Fire Hazards: Material does not burn easily but can emit toxic fumes under fire conditions including carbon oxides, nitrogen oxides.
Protective Equipment: Firefighters require self-contained breathing apparatus and full protective gear.
Other Advice: Avoid runoff from fire control as it can cause environmental contamination.
Personal Precautions: Put on appropriate protective equipment including gloves and safety goggles. Restrict unprotected individuals from entering the spill area.
Environmental Precautions: Prevent further leakage or spillage if safe. Do not allow product to reach drains, sewers, or surface water.
Clean-up Methods: Sweep up without creating dust. Place in a designated container for disposal. Clean affected area with water and detergent. Ventilate the area after cleaning.
Handling: Handle with care. Minimize dust generation and accumulation. Avoid unnecessary exposure by using laboratory safety protocols and keeping containers closed when not in use.
Storage Conditions: Store at 2-8°C in a cool, dry, well-ventilated place away from incompatible materials such as strong oxidizers.
Packaging: Keep container tightly sealed and properly labeled.
Incompatibilities: Store away from acids, bases, and oxidizing materials.
Occupational Exposure Limits: No specific occupational exposure limit established. Observe general chemical hygiene standards.
Engineering Controls: Use local exhaust ventilation to minimize dust formation. Maintain eyewash stations and safety showers within immediate work area.
Personal Protective Equipment: Use impervious gloves, lab coat, chemical safety goggles, and, in case of dust formation, a National Institute for Occupational Safety and Health (NIOSH) approved dust respirator.
Hygiene Measures: Wash hands after handling; do not eat, drink, or smoke in areas where material is used, handled, or stored.
Appearance: White to off-white crystalline powder
Odor: Odorless
pH: Neutral to slightly acidic aqueous solution
Melting Point: Decomposes at about 215°C
Solubility: Soluble in water, sparingly soluble in alcohol
Vapor Pressure: Not applicable
Boiling Point: Not applicable
Density: 1.3 g/cm³
Partition coefficient (n-octanol/water): Not determined
Flash Point: Not flammable
Chemical Stability: Stable under recommended storage and use conditions. Sensitive to light and air. May degrade on exposure to these.
Reactivity: No dangerous reactions known under normal conditions.
Incompatible Materials: Strong acids, strong bases, strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, or nitrogen oxides possible upon thermal decomposition.
Polymerization: No known hazardous polymerization.
Acute Toxicity: LD50 (Oral, rat): ~50 mg/kg
Skin Corrosion/Irritation: May cause skin irritation upon contact
Serious Eye Damage/Irritation: Can cause irritation, redness, and watering
Respiratory or Skin Sensitization: Sensitization not expected but possible with repeated exposure
Carcinogenicity: Not classified as carcinogenic under IARC, ACGIH, NTP, or OSHA
Reproductive Toxicity: Not enough data to assess
Other Effects: May cause adverse effects on cardiovascular and nervous systems if absorbed in large amounts
Aquatic Toxicity: Toxic to aquatic life in high concentrations due to adrenergic activity
Persistence and Degradability: Expected to degrade, but can persist under low oxygen conditions
Bioaccumulative Potential: Low potential for bioaccumulation, given structure and water solubility
Mobility in Soil: High water solubility suggests mobility in soil and potential to reach groundwater
Other Adverse Effects: No known significant effects, but best handled to prevent environmental release
Waste Treatment Methods: Collect and seal in labeled containers. Dispose according to federal, state, and local environmental control regulations.
Disposal of Packaging: Rinse thoroughly and dispose as hazardous chemical waste.
Special Precautions: Do not release into sewers or waterways. Incinerate in approved facilities if permitted.
UN Number: Not classified for transport under UN regulations for most quantities
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Avoid uncontrolled release.
Transport Precautions: Ship in original packaging, kept closed and labelled correctly.
TSCA Inventory Status: Listed
DSL/NDSL (Canada): Listed/checked
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200)
SARA 313: Not listed
REACH (EU): Regulation applies to use or import in Europe
Other Regulations: Compliant with US and EU pharmaceutical guidelines; not a controlled substance but only to be used by qualified professionals under applicable laws.