Material Safety Data Sheet: Diisopropyl-D-tartrate

Identification

Product name: Diisopropyl-D-tartrate
Chemical Formula: C10H18O6
Synonyms: D-tartaric acid diisopropyl ester, Tartrate acid, diisopropyl ester.
CAS Number: 32634-68-7
Use: Chiral auxiliary in organic synthesis, pharmaceutical intermediate, laboratory chemical.
Manufacturer contact: Emergency phone numbers and company specifics typically available on packaging or supplier SDS portal.

Hazard Identification

GHS classification: Not classified as hazardous under GHS.
Hazard statements: May cause minor eye or skin irritation. Inhalation of mists can cause mild respiratory tract discomfort.
Pictograms: None required by GHS.
Signal word: None required.
Precautionary statements: Avoid prolonged skin contact. Handle in well-ventilated area. Wash hands thoroughly after handling.
Routes of exposure: Eyes, skin, inhalation, ingestion.
Potential health effects: Direct contact can lead to irritation. Inhalation rarely causes discomfort, ingestion of significant quantities may create gastrointestinal upset.

Composition / Information on Ingredients

Chemical Name: Diisopropyl D-tartrate
Chemical Formula: C10H18O6
Concentration: 98-100%
Impurities: Less than 2% by weight, generally includes minor tartaric acid esters.
EC Number: 251-151-7

First Aid Measures

Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses if present. Seek medical advice if irritation develops.
Skin contact: Wash with soap and water. Remove contaminated clothing. If irritation or redness persists, get medical advice.
Inhalation: Move to fresh air. If respiratory symptoms occur, consult a healthcare professional.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical advice if feeling unwell.
Notes for physician: Symptomatic and supportive treatment.

Fire-Fighting Measures

Flammability: Not highly flammable, but may burn at high temperatures.
Suitable extinguishing media: Use alcohol-resistant foam, dry chemical, carbon dioxide, or water spray.
Unsuitable media: Direct water stream may spread burning liquid.
Special hazards: Combustion can generate carbon monoxide, carbon dioxide, and possibly acrid fumes.
Protective equipment: Wear self-contained breathing apparatus and protective clothing.
Firefighting guidance: Keep containers cool with water spray. Avoid inhaling fumes.

Accidental Release Measures

Personal precautions: Use gloves, protective eyewear, and avoid breathing vapors. Ventilate area.
Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not allow product to enter waterways or soil.
Cleanup methods: Absorb spills with inert material (sand, earth, vermiculite). Scoop up and place in closed container for waste disposal. Wash area with soap and water after removal.

Handling and Storage

Handling: Only use with proper ventilation. Wear suitable personal protective equipment to avoid direct contact. Avoid ingestion or inhalation of vapors. Do not smoke, drink, or eat near material.
Storage: Store in tightly closed container, in a cool, dry, well-ventilated space away from incompatibles like strong oxidizers and acids.
Incompatible materials: Strong oxidizers, acids, bases.
Safe storage temperature: Typically between 2°C and 8°C.
Shelf life: Stable under recommended conditions for up to 24 months.

Exposure Controls and Personal Protection

Exposure limits: No occupational exposure limits established.
Ventilation: General laboratory ventilation and local exhaust recommended.
Personal protective equipment (PPE):
- Eye protection: Safety goggles or chemical splash glasses.
- Skin protection: Chemical-resistant gloves (nitrile or rubber).
- Clothing: Lab coat or apron.
- Respiratory protection: Not usually required under normal handling. Use a respirator if exposure to vapors may occur.
Hygiene: Wash hands after use. Remove contaminated clothing and wash before re-use.
Monitoring methods: None normally required under standard laboratory settings.

Physical and Chemical Properties

Physical state: Liquid
Color: Colorless or pale yellow
Odor: Faint, mild odor
Boiling point: Approx. 300°C
Melting point: Not applicable (liquid at standard temperature)
Flash point: >110°C (closed cup)
Autoignition temperature: Not determined
Vapor pressure: Low at ambient temperature
Solubility: Slightly soluble in water, miscible in many organic solvents (ethanol, acetone)
Viscosity: Medium
Density: 1.12 g/cm³ at 20°C
pH: Not determined for neat product
Partition coefficient: Moderate, log Kow not readily available.

Stability and Reactivity

Chemical stability: Stable under recommended storage and handling conditions.
Reactivity: Non-reactive under normal conditions, can react with strong oxidizing agents or acids.
Hazardous reactions: No known hazardous polymerization.
Hazardous decomposition products: Carbon monoxide, carbon dioxide, organic vapors from thermal decomposition.
Conditions to avoid: High temperatures, open flames, incompatible materials.

Toxicological Information

Acute toxicity: No acute toxicity data available. Not regarded as acutely toxic by oral, dermal, or inhalation route.
Routes of entry: Eye, skin contact, ingestion, inhalation.
Symptoms: Skin and eye irritation, temporary discomfort from inhalation of vapor or mist, gastrointestinal upset if swallowed.
Chronic toxicity: Not reported for diisopropyl-D-tartrate.
Carcinogenicity: No evidence of carcinogenic potential from available data.
Mutagenicity/genotoxicity: No data suggesting mutagenic effects.
Reproductive toxicity: No data available.
Target organ effects: None reported in relevant concentrations.

Ecological Information

Ecotoxicity: No specific data available for aquatic toxicity. Expected to be low due to low solubility and reactivity.
Persistence and degradability: Contains ester linkages; may undergo slow hydrolysis to form tartrate and alcohol components, likely biodegradable.
Bioaccumulation potential: Low, based on structure and solubility.
Mobility in soil: Low mobility, expected to bind moderately in the environment.
Other adverse effects: Unlikely to pose major threat to environmental organisms under typical handling and disposal.

Disposal Considerations

Disposal methods: Dispose of as hazardous chemical waste according to local, regional, and national regulations.
Container disposal: Empty containers should be rinsed and managed according to standard chemical waste protocols. Do not reuse or incinerate in open environments.
Recycling: Contact waste management specialists for options if available.

Transport Information

UN Number: Not regulated as a dangerous good.
UN proper shipping name: Not assigned.
Transport hazard class: None.
Packing group: None.
Marine pollutant: Not considered a marine pollutant.
Special transport precautions: Pack in well-sealed containers, protected from breakage, in compliance with standard chemical transport requirements. Prevent leaks or significant exposure during transit.

Regulatory Information

Inventory status: Listed on TSCA, EINECS/ELINCS inventories.
Labeling: Not subject to specific labeling under local or international chemical safety regulations.
OSHA status: Not specifically regulated.
SARA Title III (Sections 302, 304, 313): Not listed.
DSL/NDSL (Canada): Listed.
Other regulations: Product may be subject to general workplace safety regulations. Users must comply with regional chemical safety, storage, and waste requirements.