Material Safety Data Sheet: Diisopropylene Glycol

Identification

Product Name: Diisopropylene Glycol
Common Synonyms: DIPG
Chemical Family: Glycol
Recommended Use: Solvent in cosmetics, perfumes, and personal care industries
Manufacturer Information: Available from primary chemical supply companies
Emergency Contact: National Poison Center, local emergency number

Hazard Identification

Hazard Statement: Slightly hazardous in case of eye and skin contact, may irritate mucous membranes, not considered harmful under normal use conditions
GHS Classification: Not classified as hazardous according to GHS standards
Pictograms: None
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Symptoms: Minor eye and skin irritation, gastrointestinal discomfort after ingestion, no significant chronic effects documented
Target Organs: Eyes, skin, digestive tract

Composition / Information on Ingredients

Chemical Identity: Diisopropylene Glycol
CAS Number: 110-98-5
Content: >99% by weight
Impurities: Trace amounts of mono- and tri-propylene glycols
Molecular Formula: C6H14O3

First Aid Measures

Inhalation: Move person to fresh air, keep comfortable, seek medical advice if symptoms such as coughing or shortness of breath develop
Skin Contact: Wash thoroughly with plenty of water and soap for several minutes, remove contaminated clothing, get medical attention if irritation persists
Eye Contact: Rinse immediately with clean water for at least 15 minutes, lift eyelids, seek attention if discomfort continues
Ingestion: Rinse mouth with water, do not induce vomiting, give water to drink, obtain medical help if large quantities are swallowed or if symptoms develop

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, alcohol-resistant foam
Special Hazards: Combustion may release carbon monoxide, carbon dioxide, and other toxic vapors
Personal Precautions: Wear self-contained breathing apparatus and protective clothing, avoid inhalation of smoke
Flash Point: Approximately 124°C (255°F)
Fire-Fighting Techniques: Cool containers with water spray, fight fire from upwind, avoid runoff entering drains

Accidental Release Measures

Personal Protection: Use chemical-resistant gloves and safety goggles, ventilate area
Spill Cleanup: Absorb with inert material (sand, soil, vermiculite), collect into labeled waste containers, clean remaining residue with water and detergent
Environmental Precautions: Prevent from entering waterways and drains, inform authorities if large spill threatens environment
Disposal: Place waste in approved chemical disposal container for proper treatment

Handling and Storage

Safe Handling: Keep containers tightly closed, avoid direct contact with skin and eyes, use mechanical ventilation in confined areas
Hygiene Measures: Wash hands thoroughly after use, do not eat, drink, or smoke in work area
Storage Conditions: Store in a cool, well-ventilated place, keep away from sources of ignition and strong oxidizers
Container Requirements: Use containers made from compatible materials such as polyethylene or stainless steel

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established; treat as nuisance vapor
Engineering Controls: Local exhaust ventilation when handling large quantities or in poorly ventilated environments
PPE Requirements: Chemical-resistant gloves, safety goggles, lab coat, appropriate footwear
Respiratory Protection: Use approved respirators if airborne concentration exceeds recommended levels or if ventilation is inadequate
Other Controls: Emergency eye-wash station and safety shower in immediate vicinity

Physical and Chemical Properties

Physical State: Clear, colorless liquid
Odor: Mild, almost odorless
Boiling Point: Around 227°C (440°F)
Melting Point: -40°C
Density: Approximately 0.98 g/cm³ (20°C)
Solubility: Miscible with water, alcohols, many organic solvents
Vapor Pressure: Very low at ambient temperature
Viscosity: Moderate, higher than water
pH: Neutral

Stability and Reactivity

Chemical Stability: Stable under routine handling and storage
Incompatible Materials: Strong acids, strong oxidizers, reactive metals
Decomposition Products: Thermal degradation may produce hazardous gases including carbon monoxide and carbon dioxide
Reactivity: No hazardous polymerization
Hazardous Reactions: None expected if handled according to standard chemical procedures

Toxicological Information

Acute Toxicity: Low toxicity, large doses may cause central nervous system effects, gastrointestinal upset
Skin Irritation: Mild, non-sensitizer
Eye Irritation: Slight irritation upon direct exposure
Inhalation Risk: Unlikely under normal use due to low volatility
Chronic Effects: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity documented in available studies
Sensitization: Does not trigger allergic reactions in most users

Ecological Information

Environmental Impact: Low potential for bioaccumulation, biodegradable
Aquatic Toxicity: Minimal toxicity to fish, daphnia, or algae at tested concentrations
Terrestrial Toxicity: Not considered threatening to soil fauna or plants
Mobility: Highly soluble, can move through soil but breaks down quickly
Persistence: Breaks down under typical environmental conditions within weeks

Disposal Considerations

Waste Treatment: Dispose of in accordance with local, regional, and national regulations
Container Disposal: Rinse with water and recycle or discard in authorized industrial landfill
Incineration: Permitted in specialized facilities with suitable controls for air emissions
Environmental Release: Prevent spills or leaks to natural waterways and municipal systems

Transport Information

UN Number: Not regulated as hazardous for transport
Transport Hazard Class: Not classified
Packing Group: Not assigned
Shipping Name: Diisopropylene Glycol
Special Transport Conditions: Protect from heat and rough handling, secure containers to prevent movement

Regulatory Information

TSCA Inventory: Listed
EINECS: Registered under EC No. 203-821-4
REACH Status: Registered or pre-registered for industrial use
SARA Title III Sections 311/312: Non-hazardous
California Proposition 65: Not listed
OSHA Status: Not a hazardous chemical as defined by OSHA Hazard Communication Standard
Label Requirements: General chemical labeling with handling and precautionary advice