Material Safety Data Sheet for Diisopropyl Tartrate

Identification

Product Name: Diisopropyl Tartrate
Synonyms: (2R,3R)-(-)-Diisopropyl tartrate, Tartaric acid diisopropyl ester
CAS Number: 2217-15-4
Recommended Uses: Chiral catalyst, chemical intermediate, synthesis of active pharmaceutical ingredients
Manufacturer/Supplier: Refer to bottle label or receiving documentation for specific company information
Emergency Phone Number: Access via local poison control center or emergency facility

Hazard Identification

GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity (Single exposure, Category 3)
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing vapor or spray dust, wash hands thoroughly after handling, wear protective gloves and eye protection, use only outdoors or in a well-ventilated area
Routes of Exposure: Eyes, skin, inhalation, ingestion

Composition / Information on Ingredients

Chemical Identity: Diisopropyl Tartrate
CAS Number: 2217-15-4
EC Number: 218-693-4
Molecular Formula: C10H18O6
Concentration: Pure substance, contains no hazardous impurities requiring disclosure under current regulations

First Aid Measures

Eyes: Flush immediately with plenty of water for 15 minutes, lifting eyelids; seek medical attention if irritation persists
Skin: Remove contaminated clothing and wash skin with mild soap and water; consult a physician upon continued irritation
Inhalation: Move person to fresh air; maintain breathing and call for medical help if symptoms such as coughing or difficulty breathing develop
Ingestion: Rinse mouth, call poison control or seek medical advice; do not induce vomiting unless told by a healthcare professional
Most Important Symptoms: Irritation of eyes, skin, or respiratory tract; reddening or itching
Note to Physicians: Treat symptoms; monitor for delayed symptoms of irritation after exposure

Fire-Fighting Measures

Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, or water spray
Unsuitable Media: Direct water jet may cause spattering
Hazards from Substance: Combustion releases carbon monoxide, carbon dioxide, and potentially irritating volatile compounds
Protective Equipment: Wear self-contained breathing apparatus, full protective clothing
Advice for Firefighters: Use water spray to cool unopened containers, prevent runoff to sewers

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ventilate area, use chemical-resistant gloves, eye/face protection, and avoid contact with spilled product
Environmental Precautions: Prevent unauthorized discharge into soil, drains, or waterways; report significant release as required
Clean-Up Methods: Absorb with inert material (sand, vermiculite), place in chemical waste container for disposal, wash area with water to remove residues

Handling and Storage

Safe Handling: Avoid contact with skin and eyes, avoid inhalation of vapors or mists, use only in well-ventilated areas, keep away from ignition sources
Hygiene Practices: Do not eat, drink, or smoke in work areas; wash hands after handling; keep work clothing separate
Storage Conditions: Store in tightly sealed original container in cool, dry, well-ventilated area away from direct sunlight, heat sources, oxidizers, acids
Incompatibilities: Strong oxidizing agents, strong acids or bases may cause hazardous reactions or decomposition

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established for diisopropyl tartrate; use general limits for nuisance dust if necessary
Engineering Controls: Local exhaust ventilation or fume hood recommended in laboratory settings
Personal Protective Equipment: Splash goggles or face shield, chemical-resistant gloves (nitrile or neoprene), lab coat or apron, use respirator with organic vapor cartridge if ventilation is inadequate
Other Controls: Ensure availability of eyewash and safety shower stations, maintain clean, clutter-free work areas

Physical and Chemical Properties

Physical State: Liquid
Color: Colorless to pale yellow
Odor: Faint, characteristic
Melting Point: -15 °C
Boiling Point: 220 - 222 °C
Flash Point: Above 113 °C (closed cup)
Solubility: Sparingly soluble in water, soluble in alcohols, organic solvents
Density: 1.13 g/cm³ at 20 °C
Vapor Pressure: Negligible at ambient temperature
pH: Not applicable (neutral ester)

Stability and Reactivity

Chemical Stability: Stable under standard conditions if kept sealed and protected from moisture
Reactivity: Not highly reactive; esters susceptible to hydrolysis under acidic or basic conditions
Hazardous Reactions: Contact with strong oxidizers may produce violent reactions
Hazardous Decomposition Products: Burns to form carbon oxides and possibly irritating fumes
Conditions to Avoid: Excessive heat, open flame, strong acids or bases, direct sunlight

Toxicological Information

Acute Toxicity: Data not fully established; not expected to be acutely toxic by oral, dermal, or inhalation exposure
Skin Irritation: Prolonged or repeated contact causes irritation or dermatitis
Eye Irritation: Causes redness, watering, possible temporary damage if not rapidly washed out
Inhalation Effects: Inhalation of vapor or mist may cause headache, respiratory discomfort, or cough
Chronic Effects: No evidence of long-term health effects or carcinogenicity from available data
Sensitization: No data suggesting respiratory or dermal sensitization

Ecological Information

Ecotoxicity: Limited evidence of aquatic toxicity; spills may cause short-term adverse effects to aquatic environments
Persistence and Degradability: Likely biodegradable by microorganisms; no long-term accumulation in the environment expected
Bioaccumulation Potential: Low potential due to solubility and expected metabolism
Mobility in Soil: Mobile in soil and water; avoid release to environment
Other Adverse Effects: No significant ozone depletion or global warming effect

Disposal Considerations

Product Disposal: Collect in appropriately labeled waste containers; incinerate or dispose in accordance with local, regional, and national regulations
Contaminated Packaging: Empty containers may contain hazardous residues; rinse thoroughly and dispose of as hazardous waste
Special Precautions: Do not discharge to sewer systems; contact licensed waste disposal contractor

Transport Information

UN Number: Not classified as dangerous for transport under ADR/RID, IMDG, or IATA rules
Proper Shipping Name: Diisopropyl Tartrate
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Environmental Hazards: Avoid uncontrolled release
Special Precautions: Protect containers from physical damage and direct sunlight during transit

Regulatory Information

Labeling: Complies with the classification and labeling requirements for hazardous substances following GHS and local regulations
TSCA Inventory: Listed
REACH Status: Not subject to registration as a monomer/intermediate
Other Regulations: No applicable OSHA highly hazardous chemicals, CERCLA, SARA Title III, or California Proposition 65 listing
International Inventories: Appears on inventory lists for North America, Europe, Japan, Australia