Material Safety Data Sheet: Diisopropyl d-tartrate

Identification

Product Name: Diisopropyl d-tartrate
Chemical Formula: C10H18O6
CAS Number: 2217-15-4
Synonyms: (2R,3R)-(+)-Diisopropyl Tartrate, Diisopropyl dithionate
Recommended Uses: Laboratory reagent, chemical industry intermediate, chiral selector in synthesis
Supplier: Chemical manufacturer or distributor details available upon request
Emergency Contact: Local poison control center or manufacturer’s emergency line

Hazard Identification

GHS Classification: Eye Irritation (Category 2), Skin Sensitization (Category 1)
Label Elements: Caution symbol, exclamation mark
Signal Word: Warning
Hazard Statements: Causes serious eye irritation; may cause allergic skin reaction
Precautionary Statements: Avoid contact with eyes and skin; use only outdoors or in a well-ventilated area; wash hands thoroughly after handling
Routes of Exposure: Skin contact, eye contact, inhalation, ingestion
Health Effects: Redness, irritation, potential rash
NFPA Rating: Health: 1, Flammability: 1, Instability: 0

Composition / Information on Ingredients

Chemical Identity: Diisopropyl d-tartrate
Concentration: 98–100%
Impurities: Minor traces of related tartrate esters (typically less than 1%)
Molecular Weight: 234.25 g/mol
EC Number: 218-680-3

First Aid Measures

Inhalation: Remove person to fresh air, support breathing as needed, seek medical care if symptoms persist
Skin Contact: Wash affected skin thoroughly with mild soap and water, remove contaminated clothing, obtain medical attention for irritation or sensitization
Eye Contact: Flush eyes with gentle flow of water for at least 15 minutes, seek medical attention immediately
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, obtain urgent medical advice
Most Important Symptoms: Irritation, rash, redness, itching
Notes for Physician: Symptomatic treatment, maintain airway and vital functions, support as needed

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical extinguishers, foam, water spray
Unsuitable Media: Direct water jets may spread material
Specific Hazards: May emit toxic smoke containing carbon oxides under intense fire; combusts at high temperatures
Protective Equipment: Firefighters should wear full protective gear, including self-contained breathing apparatus
Special Procedures: Cool fire-exposed containers, prevent runoff from reaching drains or waterways

Accidental Release Measures

Personal Precautions: Equip with gloves, safety goggles, and lab coat, use suitable chemical-resistant footwear
Environmental Precautions: Prevent entry into sewers and local waterways, restrict spread using absorbent material
Methods for Cleaning Up: Absorb with inert material such as sand or diatomaceous earth, collect and place in appropriate waste disposal container, ventilate area thoroughly, clean contaminated surfaces with soap and water
Disposal of Cleanup Materials: Contaminated materials handled as chemical waste, disposed of in accordance with regional regulations

Handling and Storage

Handling: Use in well-ventilated setting, minimize contact with skin and eyes, avoid inhalation of mist or vapors, transfer materials using appropriate tools and containment
Storage: Store in tightly sealed original containers, keep in cool, dry, and well-ventilated area, avoid exposure to direct sunlight and heat sources, segregate from strong acids and oxidizing materials
Incompatibilities: Strong oxidizers, strong acids, base-sensitive materials
Special Advice: Keep container tightly closed when not in use, label all secondary containers

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established exposure limits in local occupational safety databases
Engineering Controls: Use local exhaust ventilation, maintain negative air pressure indoors, monitor atmospheric levels for vapors
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile or equivalent), safety goggles, laboratory coat, respiratory protection if airborne exposure risk is significant (approved cartridge respirator)
Hygiene Measures: Wash hands after handling, remove and launder contaminated clothing before reuse, do not eat or drink near the handling area

Physical and Chemical Properties

Appearance: Clear, colorless to pale yellow oily liquid
Odor: Mild, fruity aroma
pH: Not applicable (non-aqueous liquid)
Melting Point: -20°C to -15°C
Boiling Point: 277°C to 279°C
Flash Point: Approximately 136°C (closed cup)
Evaporation Rate: No data available
Flammability: Combustible liquid
Vapor Pressure: Very low at room temperature
Solubility: Limited solubility in water, high solubility in organic solvents like methanol or ethanol
Partition Coefficient (n-octanol / water): Log Kow: 0.73 (estimated)
Viscosity: Syrupy liquid at room temperature
Density: Approximately 1.15 g/cm³ at 20°C

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Conditions to Avoid: Strong heat, open flames, uncontrolled oxidizing environments
Materials to Avoid: Strong acids, strong oxidizers, alkali metals
Hazardous Decomposition Products: Forms carbon monoxide, carbon dioxide, and possibly other toxic gases when burned
Polymerization: Does not undergo hazardous polymerization

Toxicological Information

Likely Routes of Exposure: Skin, eyes, ingestion, inhalation
Acute Toxicity: LD50 (oral, rat): >2000 mg/kg; low toxicity estimate for single exposure
Skin Corrosion/Irritation: Possible mild irritation on direct contact, may cause sensitization with repeated exposure
Eye Damage/Irritation: Causes significant eye irritation, redness, watering
Respiratory Sensitization: Not expected, but aerosols and vapors can irritate mucous membranes
Long-Term Effects: May sensitize skin with repeated exposure, no evidence of carcinogenicity or reproductive toxicity in available studies
Other Information: Avoid long-term inhalation or large-scale ingestion; always practice safe handling even for low-toxicity materials

Ecological Information

Toxicity to Aquatic Life: Data limited, not highly toxic in typical accidental releases, large spills can disrupt aquatic environments
Persistence and Degradability: Expected to be biodegradable in soil and water, breaks down into non-toxic components over time
Bioaccumulation: Low potential based on estimated partition coefficient
Mobility in Soil: Moderate mobility, may leach in significant quantities during major spills
Other Adverse Effects: No evidence of ozone depletion or bio-toxic breakdown products

Disposal Considerations

Waste Treatment Methods: Dispose of by incineration or through a properly permitted hazardous waste disposal contractor
Container Disposal: Triple rinse empty containers with appropriate solvent before recycling or disposal, follow local guidelines for chemical container recycling or destruction
Precautions for Disposal: Avoid release to environment, do not pour into drains or sewers
Regulatory Requirements: Comply with local, state, and federal hazardous waste and chemical disposal rules

Transport Information

UN Number: Not classified as a hazardous material for general ground or air transport
Transport Hazard Class: Not regulated under ADR, RID, IATA, or IMDG codes
Packing Group: Not applicable
Special Precautions for Transport: Use sealed containers, store upright, protect from extreme temperatures during shipping
Environmental Hazards: None significant under normal transit, avoid transport with incompatible chemicals or oxidizers
Emergency Action: In case of spill during transport contain leak, use protective gear, contact emergency services if necessary

Regulatory Information

Designation: Not specifically listed under U.S. EPA SARA Title III or European REACH SVHC lists
OSHA Status: Not regulated as hazardous chemical, exercise standard laboratory caution
DSL/NDSL Status (Canada): Present on Domestic Substances List
TSCA Status (USA): Included in the Toxic Substances Control Act inventory
Other Regulations: International chemical control laws vary, always verify compliance for country of use
Labelling Requirements: Standard chemical labeling with hazard pictograms, caution statements, supplier info, date of preparation and revision