MSDS: Diacetyl-L-tartaric Anhydride

Identification

Product Name: Diacetyl-L-tartaric anhydride
Chemical Formula: C8H10O6
Synonyms: L-(+)-Tartaric acid diacetate anhydride, DAT
CAS Number: 563-96-2
Recommended Use: Laboratory reagents, chemical synthesis, food additive (regulations vary by region)
Manufacturer/Supplier: Information should reflect the producer or distributor contact data, including address and phone number
Emergency Contact: Local emergency numbers for chemical exposure or spill response

Hazard Identification

Hazard Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity - single exposure (Category 3)
GHS Label Elements: Exclamation mark pictogram
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, causes skin irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing dust or fumes, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, wear protective gloves/protective clothing/eye protection/face protection
Other Hazards: Dust may cause irritation to the respiratory tract, prolonged or repeated exposure may trigger allergies or asthma-like symptoms in susceptible individuals

Composition / Information on Ingredients

Chemical Name: Diacetyl-L-tartaric anhydride
Chemical Identity: L-(+)-Tartaric acid diacetate anhydride
Concentration: Nearly 100% pure
Impurities or Stabilizing Additives: Trace residuals from production, not known to contribute to hazard classification
CAS Number: 563-96-2
EC Number: 209-264-9

First Aid Measures

Inhalation: Move person to fresh air, ensure unobstructed breathing, seek medical attention if symptoms develop or persist
Skin Contact: Immediately remove contaminated clothing, wash skin thoroughly with soap and water, seek medical advice if irritation occurs
Eye Contact: Rinse carefully with water for several minutes, remove contact lenses if present and easy, continue rinsing, seek medical attention if pain or redness persists
Ingestion: Rinse mouth, never induce vomiting, seek immediate medical assistance
Most Important Symptoms: Irritation to skin, eyes, respiratory tract; in serious cases, chemical burns to exposed tissue
Notes for Physician: Treat symptomatically, provide supportive care as needed

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, irritating and toxic fumes
Specific Hazards in Fire: Powdered form can form explosive mixtures with air; thermal decomposition releases acidic or pungent gases
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective gear
Special Procedures: Contain run-off to prevent entry into waterways or drains

Accidental Release Measures

Personal Precautions: Avoid inhalation of dust, avoid skin and eye contact, keep unnecessary personnel away
Protective Equipment: Wear suitable gloves, goggles, protective clothing, and NIOSH-approved respirator if dusting occurs
Emergency Procedures: Provide adequate ventilation, control sources of ignition
Containment: Sweep up and collect material without generating dust, use non-sparking tools and equipment
Clean-Up Methods: Place waste in sealed, labeled containers for proper disposal as hazardous waste
Environmental Precautions: Do not allow to enter soil, sewers, or watercourses

Handling and Storage

Precautions for Safe Handling: Minimize dust generation, use only in well-ventilated areas, avoid contact with eyes, skin, and clothing, wash hands after handling
Safe Storage Conditions: Store in a tightly sealed container in a cool, dry, well-ventilated area away from sources of ignition and incompatible substances
Incompatible Materials: Strong bases, oxidizers, moisture, reducing agents
Handling Incompatibilities: Avoid exposure to heat, air, and humidity—decomposes when wet
Storage Temperature Range: Under 25°C preferred, keep away from direct sunlight
Other Information: Keep away from food and beverages, do not reuse empty containers

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific OSHA, ACGIH, or NIOSH exposure limits established
Engineering Controls: Use process enclosures or local exhaust ventilation to minimize airborne exposure
Personal Protective Equipment: Use safety goggles with side shields, chemical-resistant gloves (nitrile or butyl recommended), lab coats, dust masks or respirators (NIOSH-approved for particulates)
Hygiene Measures: Wash hands thoroughly after handling, do not eat, drink, or smoke in work areas, remove contaminated clothing before entering eating areas
Environmental Controls: Prevent product from entering drains or watercourses

Physical and Chemical Properties

Appearance: White or off-white crystalline powder
Odor: Slightly acidic, vinegar-like odor
Odor Threshold: Not available
pH: Not available (reacts with water)
Melting Point/Freezing Point: 152-155°C
Boiling Point and Range: Decomposes before boiling
Flash Point: Not applicable for solids
Evaporation Rate: Not available
Flammability: Not easily ignitable but can burn; dust may form explosive mixtures with air
Vapor Pressure: Negligible at 20°C
Vapor Density: Not available
Relative Density: About 1.4 g/cm³
Solubility: Hydrolyzes in water, soluble in alcohols and acetone
Partition Coefficient n-octanol/water: Not determined
Auto-Ignition Temperature: Not available
Decomposition Temperature: Above 155°C
Viscosity: Not applicable
Other Information: Forms acetic acid on hydrolysis

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, degrades rapidly if exposed to moisture
Reactivity: Reacts exothermically with water and strong bases
Possible Hazardous Reactions: Decomposition with release of acetic acid and tartaric acid
Conditions to Avoid: Avoid moisture, heat, humidity, exposure to air
Materials to Avoid: Water, strong bases, oxidizing or reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, acetic acid, tartaric acid

Toxicological Information

Likely Routes of Exposure: Inhalation, skin or eye contact, ingestion
Acute Toxicity: Oral LD50 not well established, expected to be low to moderate based on similar anhydrides
Skin Corrosion/Irritation: Causes irritation; may cause redness, pain, or blistering
Serious Eye Damage/Irritation: Causes significant irritation, may progress to corneal injury with extended exposure
Respiratory or Skin Sensitization: May cause respiratory or skin sensitization in certain individuals
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No data available on reproductive toxicity
Specific Target Organ Toxicity - Single Exposure: May cause respiratory tract irritation
Specific Target Organ Toxicity - Repeated Exposure: Data insufficient
Other Effects: Prolonged or repeated contact can worsen irritation or lead to allergic reactions

Ecological Information

Ecotoxicity: Data on aquatic toxicity not well established, hydrolyzes to tartaric acid and acetic acid over time
Environmental Fate: Rapidly hydrolyzes in presence of moisture; breakdown products are biodegradable
Persistence and Degradability: Not expected to persist, biodegradable by hydrolysis and microbial action
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: Mobile due to solubility of hydrolysis products
Other Adverse Effects: Release of acidifying substances may alter waterway pH if discharge is excessive

Disposal Considerations

Disposal Methods: Subject to local, regional, and national regulations; incinerate or landfill in compliance with government requirements
Container Disposal: Do not reuse containers, triple rinse and puncture before disposal
Waste Codes: Check with local environmental agency for proper classification
Precautions: Avoid dispersal of dust in air, avoid discharge to the environment
Special Precautions: Use licensed chemical waste contractor for bulk quantities

Transport Information

UN Number: Not regulated under most international transport guidelines
UN Proper Shipping Name: Not regulated

Transport Hazard Class: Not classified
Packing Group: Not applicable
Environmental Hazards: Not considered marine pollutant
Special Precautions for User: In case of bulk transport, ensure containers remain tightly sealed and protected from moisture

Regulatory Information

OSHA Status: Not specifically regulated; general requirements for safe handling apply
TSCA Inventory: Listed
REACH Status: Registered by some suppliers in compliance with EU regulations
Other US Federal Regulations: Not subject to SARA 313, not listed as a hazardous air pollutant
State Regulations: Not specifically regulated in California Proposition 65
WHMIS Classification (Canada): D2B (toxic material causing other toxic effects)
Other International Regulations: Check with local jurisdiction for applicable workplace or transport laws