Material Safety Data Sheet: Di(propylene glycol) Methyl Ether Acetate Mixture of Isomers

1. Identification

Product Name: Di(propylene glycol) methyl ether acetate (mixture of isomers)
Common Trade Names: DPM Acetate, Dipropylene glycol monomethyl ether acetate
Chemical Family: Glycol ether ester, acetate
CAS Number: 88917-22-0
Recommended Use: Industrial solvent, coatings, paints, inks, cleaning agents
Manufacturer: Contact details include address, emergency telephone, email
Emergency Contact: National chemical emergency response center, local fire department, poison control

2. Hazard Identification

GHS Classification: Flammable liquid category 4, eye irritation category 2, skin irritation category 3
Signal Word: Warning
Hazard Statements: Combustible liquid, causes mild skin irritation, causes eye irritation
Pictograms: Exclamation mark, flame
Precautionary Statements: Avoid breathing vapors, wash skin thoroughly after handling, use only outdoors or in well-ventilated areas, keep away from heat or sparks, keep container tightly closed, store in cool, dry place
Other Dangers: Vapor may irritate respiratory tract, inhalation overexposure may cause headaches or drowsiness

3. Composition / Information on Ingredients

Main Ingredient: Di(propylene glycol) methyl ether acetate
Concentration: >95% (mixture of isomers)
Impurities: Trace amounts of di(propylene glycol) methyl ether
Molecular Formula: C10H20O4
Molecular Weight: 204.26 g/mol
Other Components: Not known to contain hazardous stabilizers, dyes or additives in concentrations significant for classification

4. First Aid Measures

Inhalation: Move person to fresh air, keep comfortable, seek medical attention if symptoms persist or breathing becomes difficult
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing and shoes, seek medical attention for irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present, seek medical attention for persistent discomfort
Ingestion: Rinse mouth, call a physician or poison center immediately, do not induce vomiting unless instructed
Symptoms of Exposure: Headaches, dizziness, mild respiratory irritation, skin redness, eye discomfort
Advice for Rescuers: Use appropriate personal protective equipment to avoid exposure while assisting victim

5. Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam, water spray
Unsuitable Extinguishing Media: Strong water jets
Specific Hazards: Vapors heavier than air, may form explosive mixtures with air in confined spaces, thermal decomposition may form carbon monoxide, carbon dioxide, acrid smoke, and toxic fumes
Protective Equipment for Firefighters: Full protective clothing including self-contained breathing apparatus required
Firefighting Procedures: Use fog nozzles to apply water spray for cooling, prevent firewater runoff from entering drains, ventilate area after fire is out

6. Accidental Release Measures

Personal Precautions: Eliminate all sources of ignition, provide adequate ventilation, evacuate unnecessary personnel, avoid inhalation of vapors
Protective Equipment: Wear gloves, eye protection, and suitable protective clothing
Environmental Precautions: Prevent entry into drains, surface water or groundwater, contain spill with inert absorbent
Cleanup Methods: Collect spilled liquid with non-combustible absorbent such as sand, earth, or vermiculite, shovel into containers for disposal, clean remaining residue with detergent and water
Waste Disposal: Dispose as hazardous waste according to local regulations

7. Handling and Storage

Safe Handling Advice: Avoid contact with eyes and skin, avoid inhaling vapor or mist, use with explosion-proof equipment, ground containers during transfer
Technical Measures: Use only non-sparking tools, take precautions against static buildup
Storage Conditions: Store in tightly closed original containers, keep in cool, well-ventilated area away from heat, sparks, and open flame, avoid direct sunlight
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Handling Precautions: Do not reuse containers, wash thoroughly after handling

8. Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limit established by OSHA or ACGIH; maintain airborne concentrations as low as reasonably achievable
Engineering Controls: Use local exhaust ventilation, process enclosures
Respiratory Protection: Use NIOSH-certified organic vapor respirators if ventilation is inadequate
Skin Protection: Wear chemical-resistant gloves such as butyl rubber or nitrile, long sleeves, chemical-resistant apron
Eye Protection: Wear safety glasses with side shields or chemical splash goggles
Hygiene Measures: Wash hands before breaks, after handling, and before eating or smoking

9. Physical and Chemical Properties

Physical State: Clear liquid
Color: Colorless to pale yellow
Odor: Slight ester odor
Boiling Point: 230-245°C
Flash Point: 95°C (closed cup)
Melting Point: -55°C
Vapor Pressure: <0.1 mmHg at 20°C
Relative Density: 0.995-1.005 (water=1)
Solubility in Water: Moderate
Viscosity: 3.5 mPa.s at 25°C
pH: Not applicable
Partition Coefficient (log Kow): 0.8-1.2
Evaporation Rate: <1 (butyl acetate=1)

10. Stability and Reactivity

Chemical Stability: Stable under normal ambient and anticipated storage and handling conditions
Conditions to Avoid: Elevated temperatures, ignition sources, direct sunlight
Incompatible Materials: Strong oxidizing agents, acids, bases
Hazardous Reactions: No hazardous polymerization expected
Decomposition Products: Carbon monoxide, carbon dioxide, possibly acetic acid fumes, unidentified organic compounds on combustion

11. Toxicological Information

Acute Toxicity (Oral): LD50 (rat) > 3000 mg/kg
Acute Toxicity (Dermal): LD50 (rabbit) > 2000 mg/kg
Acute Toxicity (Inhalation): No mortality observed at saturated vapor concentration
Skin Corrosion/Irritation: Mild irritation may occur
Eye Damage/Irritation: Causes eye irritation
Sensitization: Not expected to cause skin sensitization
Mutagenicity: No evidence of genetic toxicity in standard assays
Carcinogenicity: No evidence based on animal studies or epidemiology
Repeated Dose Toxicity: Prolonged or repeated exposure may cause narcotic effects or mild liver and kidney changes
Target Organs: Central nervous system, liver, kidneys

12. Ecological Information

Acute Aquatic Toxicity: LC50 (fish, 96 hr) > 100 mg/L
Chronic Aquatic Toxicity: Not expected at typical environmental concentrations
Persistence and Degradability: Readily biodegradable, rapid mineralization by environmental microbes
Bioaccumulation: Low potential, log Kow values suggest limited bioconcentration
Mobility in Soil: Moderate, leaching possible in permeable soils
Other Adverse Effects: Avoid uncontrolled environmental discharge, possible local oxygen depletion from large releases

13. Disposal Considerations

Waste Treatment Methods: Do not dump into sewers or natural waterways, send to licensed hazardous waste incinerator or appropriate chemical disposal
Contaminated Packaging: Rinse thoroughly, puncture and dispose in accordance with local regulations
Special Instructions: Consult regional environmental authority for specific local guidelines
Regulatory Waste Code: As assigned by local, state or federal authorities

14. Transport Information

UN Number: Not regulated for ground, air or sea transport in most regions under UN recommendations
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not recognized as marine pollutant
Special Precautions: Package securely, avoid releasing material during transit

15. Regulatory Information

TSCA: Listed on United States Toxic Substances Control Act Inventory
EINECS/ELINCS: Listed in European chemical inventories
DSL/NDSL (Canada): Listed
OSHA: Not listed as hazardous under Hazard Communication Standard, but observe general chemical safety
SARA Title III: Not subject to reporting under Sections 302, 304, 313
California Prop 65: Not listed
Other Regulations: Users should consult country, state, provincial, or local regulations for additional requirements and guidance relevant to this material