Product Name: Di(propylene glycol) dimethyl ether
Chemical Family: Glycol Ethers
Chemical Formula: C8H18O3
Synonyms: Dipropylene glycol dimethyl ether, DMM, DiPG DME
Recommended Use: Industrial solvent, Cleaning agent, Chemical processing
Manufacturer: Major chemical producers (consult supplier information)
Emergency Contact: Local poison control center; 24-hour manufacturer emergency line
Classification: Flammable liquid (Category 3), Eye irritation (Category 2B), Skin irritation (Category 3)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor; Causes mild skin irritation; Causes eye irritation
Precautionary Statements: Keep away from heat/sparks/open flames/hot surfaces. No smoking. Wear protective gloves/protective clothing/eye protection/face protection. Keep container tightly closed. Wash hands thoroughly after handling.
GHS Label Elements: Flame symbol, Exclamation mark
Chemical Name: Di(propylene glycol) dimethyl ether
CAS Number: 111109-77-4
Concentration (wt%): >99%
Impurities: Less than 1% by weight, unreacted glycols or ethers, not expected to present chronic health effects at these concentrations
Inhalation: Move person to fresh air. Seek medical advice if symptoms like headache, dizziness, or drowsiness persist.
Skin Contact: Remove contaminated clothing. Wash skin with soap and water for at least 15 minutes. If irritation persists, consult a physician.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if worn and easy to do. Continue rinsing. Seek medical attention if irritation develops.
Ingestion: Rinse mouth. Do not induce vomiting. Get medical advice/attention if you feel unwell or in case of large ingestion.
Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Unsuitable Extinguishing Media: High pressure water streams can spread fire.
Specific Hazards: Vapors are heavier than air and can travel long distances to ignition sources. Containers can rupture under fire conditions. Toxic gases like carbon monoxide and carbon dioxide may be released.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus (SCBA) and full protective gear.
Firefighting Instructions: Cool exposed containers with water spray. Stay upwind to avoid toxic vapor exposure.
Personal Precautions: Evacuate area and eliminate ignition sources. Ventilate area. Wear suitable protective clothing, gloves, goggles.
Spill Response: Absorb spill with inert material (sand, earth). Collect and place in suitable, labeled containers. Avoid entry into sewers or waterways.
Environmental Precautions: Prevent further leakage or spillage if safe to do so. Notify environmental authorities if product enters rivers, lakes, or drains.
Decontamination: Clean area thoroughly with water and detergent after removal of substance.
Handling: Use in well-ventilated area. Avoid inhalation of vapors and contact with skin, eyes, and clothing. Ground/bond containers during transfer to avoid static discharge. Keep away from heat, sparks, open flames.
Storage Conditions: Store in tightly closed, properly labeled containers in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers and acids. Protect from sunlight and ignition sources.
Special Precautions: Keep containers upright to prevent leaks. Check regularly for leaks or corrosion. Practice good hygiene – wash hands after handling.
Engineering Controls: Adequate ventilation such as local exhaust or fume hood. Use explosion-proof equipment where appropriate.
Occupational Exposure Limits: No established OSHA or ACGIH limits; minimize exposure.
Personal Protective Equipment (PPE):
Gloves: Nitrile, butyl rubber, or other chemical-resistant gloves.
Eye Protection: Safety glasses or goggles with side shields.
Respiratory Protection: If airborne concentrations are high, use NIOSH-approved organic vapor respirator.
Clothing: Long-sleeved clothing to avoid skin contact.
Appearance: Clear, colorless liquid
Odor: Slight, ether-like
Odor Threshold: Not established
pH: Not applicable (neutral substance)
Melting Point/Freezing Point: -82°C
Boiling Point/Range: 175-210°C (varies with isomer content)
Flash Point: 72°C (closed cup)
Evaporation Rate: Slower than diethyl ether
Flammability: Flammable liquid
Upper/Lower Flammability Limits: 1.3% / 8.5% (v/v in air)
Vapor Pressure: 0.3 mmHg at 20°C
Vapor Density: Heavier than air
Relative Density: 0.92 g/cm³ at 20°C
Solubility: Soluble in water, alcohol, most organic solvents
Partition Coefficient (log Kow): <1
Decomposition Temperature: Not determined
Viscosity: 3 mPa·s at 20°C
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Normally unreactive, but reacts with strong oxidizing agents.
Hazardous Reactions: Not known under normal conditions.
Conditions to Avoid: Heating, sparks, open flames, static electricity.
Incompatible Materials: Strong acids, strong bases, oxidizers.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, other toxic fumes.
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion.
Acute Toxicity: Low oral toxicity; inhalation may cause headache, dizziness, or drowsiness.
Skin Corrosion/Irritation: Mild irritation possible after prolonged exposure.
Serious Eye Damage/Irritation: Causes eye irritation in some individuals.
Respiratory or Skin Sensitization: Not a sensitizer in animal studies.
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA.
Mutagenicity and Reproductive Toxicity: Not known to cause genetic or reproductive harm at industrial exposure levels.
Chronic Effects: Chronic exposure may cause central nervous system effects, similar to many glycol ethers.
Medical Symptoms: May include nausea, headache, fatigue, dermatitis with repeated contact.
LD50 (Oral/Rat): >3,000 mg/kg
Ecotoxicity: Low toxicity to aquatic life based on available data.
Persistence and Degradability: Readily biodegradable in water and soil.
Bioaccumulative Potential: Low; expected to have low bioaccumulation due to high water solubility and low log Kow.
Mobility in Soil: High mobility in water; unlikely to strongly adsorb to soil.
Other Adverse Effects: Large spills may cause localized harm to aquatic environments by reducing oxygen levels.
Product Disposal: Dispose of in accordance with federal, state, and local regulations. Preferred disposal method in authorized chemical incinerator or by licensed hazardous waste contractor.
Container Disposal: Empty containers should be triple-rinsed, punctured, and sent to licensed drum reconditioner or incinerator.
Special Precautions: Do not allow product or rinsates to reach water sources, drains, or sewers.
UN Number: UN 3272
Proper Shipping Name: Ethers, n.o.s. (Dipropylene glycol dimethyl ether)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Environmental Hazards: None known; not classified as marine pollutant
Special Transport Precautions: Transport upright and securely. Keep away from heat and sources of ignition. Ensure all transport documents comply with ADR, RID, IMDG, IATA regulations as appropriate.
SARA Title III: Not subject to reporting under Sections 302, 304, 313
TSCA Inventory: Listed
REACH Registration: Pre-registered or registered in the EU
OSHA HazCom: Classified as hazardous
Canada WHMIS: B2 (Flammable liquid), D2B (Toxic Materials causing other toxic effects)
Labeling Requirements: GHS-compliant labeling, including hazard pictograms, signal word, hazard and precautionary statements
Other National Regulations: Comply with state/provincial/local requirements for storage and handling
Providing high-quality chemical products and logistics solutions for global trade partners.
