Material Safety Data Sheet for Di-P-Toluoyl-L-Tartaric Acid

1. Identification

Product Name: Di-P-Toluoyl-L-Tartaric Acid
Chemical Name: L-Tartaric acid, di-p-toluoyl ester
Synonyms: DPTTA, (2R,3R)-2,3-Dihydroxybutanedioic Acid, 4-methylbenzoyl ester
CAS Number: 32634-68-7
Recommended Uses: Chiral resolving agent, organic synthesis
Manufacturer/Supplier: Listed with chemical manufacturers and suppliers globally
Emergency Contact: Provided by local distributor or chemical safety database
Contact Phone Number: Refer to supplier’s safety office

2. Hazard Identification

GHS Classification: Not classified as hazardous according to GHS standards
Hazard Statements: May cause mild eye, skin, or respiratory tract irritation
Pictogram: No symbol required under standard labeling guidelines
Signal Word: None
Precautionary Statements: Avoid dust formation; prevent contact with eyes, skin, and clothing; use with adequate ventilation; wash thoroughly after handling
Potential Health Effects: Eyes—May cause irritation, tearing, or redness; Skin—Prolonged contact may dry or irritate; Inhalation—Dusts may irritate the respiratory tract; Ingestion—Large amounts may lead to mild stomach upset
Environmental Hazards: Not considered especially hazardous to the environment, but best practice encourages minimizing all chemical releases

3. Composition / Information on Ingredients

Chemical Identity: Di-P-Toluoyl-L-Tartaric Acid
CAS Number: 32634-68-7
Concentration: 98-100% (technical grade)
Impurities: May contain trace levels of related organic acids and solvents from manufacturing
Molecular Formula: C20H18O8
Molecular Weight: 386.35 g/mol
Mixture: No, single-component substance

4. First Aid Measures

Eye Contact: Rinse eyes gently with water for at least fifteen minutes, lift eyelids to ensure full cleaning, remove contact lenses if present, seek medical attention if irritation persists
Skin Contact: Remove contaminated clothing, wash affected skin with mild soap and water for several minutes, get medical help if redness or itching stays
Inhalation: Move person to fresh air, keep comfortable, seek medical attention if coughing or discomfort worsens
Ingestion: Rinse mouth thoroughly, drink water if conscious, do not induce vomiting unless directed by medical personnel, call poison control if feeling unwell
Personal Protection for First Aid Responders: Use gloves, safety goggles, and dust mask if available to prevent further contact

5. Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam, water spray
Unsuitable Extinguishing Media: Strong water jets may spread burning dust
Specific Hazards: Combustible dust in fine particles, toxic fumes of carbon oxides and methyl compounds may evolve in case of fire
Special Protective Equipment for Firefighters: Full protective gear with self-contained breathing apparatus
Special Procedures: Move containers from fire area if safe; use water to cool exposed containers, avoid inhaling fumes

6. Accidental Release Measures

Personal Precautions: Use gloves, goggles, dust mask; avoid breathing dust; prevent contact with skin and eyes
Environmental Precautions: Prevent release to soil, drains, or waterways, pick up spills promptly
Methods for Containment and Cleaning Up: Avoid dry sweeping, use damp cloth or vacuum with HEPA filter, collect spilled powder in sealed, labeled containers, ventilate area well
Reference to Other Sections: Refer to handling precautions and personal protection guidance for safe cleanup practices
Disposal Considerations: Dispose of contaminated materials according to local laws, see section on disposal for details

7. Handling and Storage

Safe Handling: Avoid creating dust, use only in well-ventilated or exhaust hood areas, wear suitable personal protective equipment, wash hands after handling
Storage Conditions: Keep container tightly sealed in cool, dry, and well-ventilated place, store away from incompatible substances such as strong oxidizers
Incompatibles: Strong bases, oxidizing agents
Special Precautions: Label containers clearly, avoid storing near food or drink, keep out of reach of children or unauthorized personnel

8. Exposure Controls / Personal Protection

Occupational Exposure Limits: No established exposure limits for this material as of current regulatory recommendations
Engineering Controls: Use local exhaust ventilation, fume hood for small-scale operations; avoid open handling without containment
Personal Protective Equipment: Protective gloves (nitrile or latex), safety goggles or face shield, laboratory coat or suitable clothing, dust respirator if dust forms
Hygiene Measures: Wash hands before eating, drinking, smoking, and after using the substance; avoid eating or storing food in working areas
Environmental Exposure Controls: Prevent dust release to drains, water systems, or open environment by using closed systems whenever possible

9. Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless or faintly aromatic
Odor Threshold: Not determined
pH: No data available (insoluble in water)
Melting Point/Freezing Point: 163-167 °C
Boiling Point: Decomposes before boiling
Flash Point: Not determined, combustible as a fine powder
Evaporation Rate: Not applicable
Flammability: Combustible dust in fine or dispersed state
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Relative Density: ~1.4 g/cm³
Solubility: Poorly soluble in water; soluble in ethanol, methanol, acetone, and other organic solvents
Partition Coefficient (n-octanol/water): Not available
Auto-Ignition Temperature: Not known
Decomposition Temperature: Above 170 °C
Viscosity: Not applicable (solid)

10. Stability and Reactivity

Chemical Stability: Stable at ambient temperature in sealed containers
Reactivity: Does not undergo hazardous reactions under normal storage and handling
Conditions to Avoid: Strong heat, ignition sources, open flame, direct sunlight
Incompatible Materials: Strong oxidizing agents, strong bases, acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, and toluene derivatives by thermal decomposition
Polymerization: Will not occur under standard storage conditions

11. Toxicological Information

Acute Toxicity: No known acute toxicity data for humans, believed to be low based on structure
Skin Corrosion/Irritation: May cause mild skin irritation on prolonged or repeated contact
Serious Eye Damage/Irritation: Dust may provoke transient eye irritation
Respiratory Sensitization: Prolonged exposure to dust can irritate mucous membranes
Germ Cell Mutagenicity: Not classified or tested
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No data or evidence of reproductive hazards
Specific Target Organ Toxicity (Single/Repeated Exposure): Not observed in available literature
Aspiration Hazard: Not anticipated with solid material
Potential Health Effects (Short-term/Long-term): Mild transient eye and skin irritation; high exposures to dust for prolonged periods may affect respiratory comfort

12. Ecological Information

Ecotoxicity: Low hazard to aquatic or terrestrial organisms under normal circumstances
Persistence and Degradability: Believed to degrade through biotic and abiotic means; detailed breakdown products not established
Bioaccumulative Potential: Not expected to bioaccumulate based on low solubility and lack of evidence
Mobility in Soil: Not mobile due to low water solubility
Other Adverse Effects: Minimize release to environment, avoid disposal in natural water bodies

13. Disposal Considerations

Disposal Methods: Dispose as non-hazardous solid waste in accordance with local, regional, and national regulations
Contaminated Packaging: Empty packaging should be cleaned and recycled or disposed of safely as chemical waste
Special Precautions: Avoid generating dust when disposing, follow local environmental protection rules
Incineration: Suitable for industrial incineration when permitted by regulations
Do Not: Release to sewers or natural waterways

14. Transport Information

UN Number: Not regulated for land, sea, or air transport
UN Proper Shipping Name: Not a dangerous good
Transport Hazard Class: Not classified
Packing Group: Not applicable
Special Precautions: Use secure, closed packaging; avoid breakage or spillage during transit
Environmental Hazards: Not a marine pollutant
Transport in Bulk: Not relevant for small or laboratory quantities

15. Regulatory Information

United States (OSHA): Not classified as hazardous
TSCA Inventory: Listed or accepted for research
EU (REACH): Not registered in large volumes, exempted or subject to low volume pre-registration
Canada (DSL/NDSL): Substance eligibility depends on supplier listing
Other Requirements: Product labeling must follow chemical safety and workplace labeling guidelines; Safety Data Sheet must be available for handling
Workplace Restrictions: Use by trained staff in occupational settings, reference local employee protection statutes