Product Name: D-(-)-Threo-2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol
Synonyms: D-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol hydrochloride, D-(-)-Threo-p-Nitrobenzyl-2-amino-1,3-propanediol
Chemical Formula: C9H12N2O4
CAS Number: 7427-85-6
Recommended Use: Laboratory research, chemical synthesis, pharmaceutical intermediate
Supplier Information: Refer to specific supplier for address, telephone, and emergency phone number information
GHS Classification: Acute toxicity (oral, dermal, inhalation); Eye irritation; Skin irritation; Specific organ toxicity
Label Elements: Warning symbols covering health hazard, exclamation mark
Hazard Statements: Causes damage to organs, harmful if swallowed or inhaled, may cause respiratory irritation, causes eye and skin irritation
Precautionary Statements: Avoid breathing dust/mist/vapors, wash hands thoroughly after handling, use only outdoors or in well-ventilated area, wear protective gloves/protective clothing/eye protection/face protection
Chemical Name: D-(-)-Threo-2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol
CAS Number: 7427-85-6
Concentration: 98-100% by weight
Impurities/Additives: No significant impurities affecting classification
Inhalation: Remove person to fresh air. Keep comfortable for breathing. Seek medical attention if symptoms persist.
Skin Contact: Remove contaminated clothing. Wash skin with soap and water. Get medical help if irritation continues.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical advice.
Ingestion: Rinse mouth. Do not induce vomiting. Seek immediate medical attention or contact local Poison Control.
Symptoms: Cough, sore throat, shortness of breath, skin redness, rash, burning sensation, nausea, headache
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Media: Water jets (may spread fire)
Special Hazards: Emits toxic fumes under fire conditions (nitrogen oxides, carbon monoxide, carbon dioxide), combustible dust hazard possible
Protective Equipment: Firefighters need full protective gear, self-contained breathing apparatus, avoid inhaling vapors
Fire-Fighting Instructions: Move containers from fire if it can be done safely. Use water spray to cool surfaces exposed to fire.
Personal Precautions: Evacuate unnecessary personnel, provide adequate ventilation, avoid dust formation, avoid breathing vapors
Protective Equipment: Chemical-resistant gloves, protective clothing, dust mask or respirator, eye protection
Environmental Precautions: Prevent entry into drains, sewers, waterways, or soil
Clean-up Methods: Absorb with inert material (sand, vermiculite), collect in sealed containers for disposal, wash spill site after material pickup, avoid dust generation, dispose following local regulations
Emergency Procedures: Notify appropriate authorities, ventilate area
Handling: Use in chemical fume hood, wear appropriate PPE, avoid contact with skin, eyes, and clothing, avoid formation and inhalation of dust and aerosols, no eating, drinking, or smoking in work area
Storage: Store in tightly closed container at room temperature, in dry, cool, well-ventilated place, protect from incompatible substances (strong oxidizers, acids), label containers clearly, secure against unauthorized access
Occupational Exposure Limits: No established OSHA, ACGIH, or NIOSH exposure limits
Engineering Controls: Use local exhaust or general ventilation to minimize dust/vapor exposure, chemical fume hood recommended
Personal Protective Equipment (PPE): Nitrile gloves, laboratory coat, chemical safety goggles, NIOSH-approved respirator in operations generating dust/vapors
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing, keep work area clean, never reuse contaminated PPE
Appearance: Yellow to tan crystalline powder
Odor: Odorless or faint chemical odor
Molecular Weight: 212.20 g/mol
Boiling Point: Decomposes before boiling
Melting Point: 142-146°C
Solubility: Soluble in water, soluble in ethanol
pH: Not available
Vapor Pressure: Not determined
Density: Not established
Other: Stable under recommended conditions, may become hygroscopic
Chemical Stability: Stable under normal laboratory conditions
Reactivity: Incompatible with strong oxidizing agents, strong acids
Hazardous Reactions: No polymerization expected
Hazardous Decomposition Products: Toxic fumes including nitrogen oxides, carbon monoxide, carbon dioxide upon combustion or decomposition
Conditions to Avoid: Excess heat, moisture, dust formation, open flames, static discharge
Likely Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Effects: Toxic if swallowed or inhaled, may irritate respiratory tract, may cause skin and eye irritation
Chronic Effects: No long-term data available, use with caution
LD50 (Oral, Rat): Data not readily available; use extreme caution
Irritation Data: Causes irritation to eyes, skin, and mucous membranes
Sensitization: May cause allergic reactions in sensitive individuals
Carcinogenicity, Mutagenicity, Teratogenicity: No data available, not listed by IARC, NTP, OSHA
Toxicity to Aquatic Life: Not classified but potentially hazardous to aquatic organisms
Persistence and Degradability: Not readily biodegradable; persistence in aquatic environment possible
Bioaccumulation Potential: Not expected to bioaccumulate significantly
Mobility in Soil: Moderate mobility possible, water solubility may increase risk of leaching
Other Adverse Effects: Prevent release to the environment, no known significant environmental effects or critical hazards with responsible handling
Waste Treatment Methods: Dispose in accordance with federal, state, and local regulations
Product Disposal: Place in sealed, labeled containers for hazardous chemical waste disposal
Contaminated Packaging: Rinse and dispose of as hazardous waste
Precautions: Do not allow material to enter drains, surface water, or soil. Do not mix with other wastes. Mercury, heavy metals, and toxic organics require separate disposal streams.
UN Number: Not classified as a hazardous material under UN, IATA, or DOT for transport
Proper Shipping Name: Chemical substances, non-hazardous for transport
Hazard Class: Not assigned
Packing Group: Not applicable
Environmental Hazards: Not regulated as marine pollutant
Transport Precautions: Keep package intact and secure, prevent breakage and spillage, transport in accordance with internal and local guidelines
TSCA (USA): Not listed
DSL/NDSL (Canada): Not listed
REACH (EU): Substance registration may be required depending on use
OSHA Hazards: Harmful by ingestion and inhalation, irritant
Other Regulations: Comply with national chemical substance inventory regulations; check specific country requirements for registration or reporting
Labeling Requirements: Chemical container labeling with hazard information required for workplace safety
Other Information: This MSDS complies with requirements for communication of hazards and safety information, regular review for regulatory changes encourages proactive compliance
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