Product Name: D(-)-Threo-2-amino-1-(4-nitrophenyl)-1,3-propanediol (L-Base)
Chemical Formula: C9H12N2O4
Molecular Weight: 212.20 g/mol
Synonyms: L-Base; D(-)-Threo-2-amino-1-(p-nitrophenyl)-1,3-propanediol
CAS Number: 36821-12-4
Product Use: Laboratory research, intermediate in specific pharmaceutical applications
Manufacturer: Company contact details available upon request; refer to supplier for location and emergency contact
Classification: Not classified as hazardous under GHS standards unless large quantities or powder are released
Signal Word: Warning
Hazard Statements: May cause mild irritation by inhalation, skin contact, or ingestion, particularly at high exposures
Pictograms: Exclamation mark (skin/eye irritant)
Precautionary Statements: Avoid dust formation, minimize inhalation, prevent exposure without proper protection, wash thoroughly after handling
Emergency Overview: Bright yellow crystalline solid, may cause respiratory, skin, or eye irritation, do not taste or eat, keep away from incompatible materials
Chemical Name: D(-)-Threo-2-amino-1-(4-nitrophenyl)-1,3-propanediol
Concentration: ≥98% pure (remainder: trace solvent or moisture)
Impurities: None expected above reporting thresholds
Common Additives: Not applicable
Incompatible Substances: Strong oxidizing or reducing agents, acid chlorides, acid anhydrides
Inhalation: Move to fresh air, seek medical attention if irritation occurs, monitor for any shortness of breath or coughing
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, seek medical attention if irritation persists
Eye Contact: Flush with water for several minutes, remove contact lenses, continue flushing if irritation persists, get medical attention
Ingestion: Rinse mouth, drink water to dilute, avoid inducing vomiting, call poison control or a physician for advice
Medical Attention: Show this data sheet to medical providers
Most Important Symptoms: Local irritation, possible allergic response in sensitive individuals, rarely prolonged breathing discomfort
Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Unsuitable Media: Direct water jets, which can scatter powder
Special Hazards: Combustion can release nitrogen oxides, carbon oxides, noxious fumes
Protective Equipment: Wear self-contained breathing apparatus, chemical protective clothing, gloves, avoid smoke exposure
Advice for Firefighters: Tackle fire from upwind position, keep cool surfaces with water spray, prevent run-off from entering water sources
Personal Precautions: Wear gloves, goggles, dust mask or respirator, protective clothing
Environmental Precautions: Prevent spill or powder from entering drains, watercourses, or soil
Cleanup Methods: Collect spillage using scoop or vacuum with HEPA filter, transfer to waste container for disposal, ventilate area, wash surfaces with detergent and water
Additional Advice: Avoid creating or breathing dust, dispose of waste according to local regulations
Handling: Use within ventilated fume hood, wear standard laboratory protective equipment, handle away from sources of ignition or heat, use tools to minimize direct contact
Storage: Store in tightly closed container, cool, dry, well-ventilated area, keep away from incompatible chemicals, clearly label storage with product and hazard information
Special Storage Requirements: Protect from excessive heat, direct sunlight, and moisture, separate from acids, oxidizing or reducing agents
Occupational Exposure Limits: No established limit for this compound; handle as particulates not otherwise classified (PNOC)
Engineering Controls: Use in fume hood or well-ventilated workspace, local exhaust ventilation recommended
Respiratory Protection: NIOSH-approved respirator for particulates if dust is generated, otherwise not needed
Hand Protection: Nitrile or chemical-resistant gloves, check for integrity before use
Eye Protection: Chemical safety goggles, face shield for large volumes
Skin Protection: Laboratory coat, sleeves, closed shoes, avoid skin exposure
Hygiene Practices: Wash hands thoroughly after handling, do not eat, drink, or smoke in work areas, remove contaminated clothing promptly
Appearance: Yellow crystalline powder
Odor: Odorless or faint chemical scent
Odor Threshold: Not determined
pH: 5.0–7.0 in aqueous solution
Melting Point: 123–127 °C
Boiling Point: Not applicable (decomposes on heating)
Flash Point: Not determined
Evaporation Rate: Not available
Flammability: Not classified as flammable
Vapor Pressure: Negligible at ambient temperature
Vapor Density: Not available
Relative Density: Approx. 1.45 g/cm³
Solubility: Moderately soluble in water, soluble in ethanol and methanol
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: Not determined
Decomposition Temperature: >150 °C
Viscosity: Not applicable (solid material)
Molecular Structure: Contains both amino and nitro functional groups
Chemical Stability: Stable at room temperature under recommended storage conditions, degrades under prolonged exposure to strong sunlight or heat
Possibility of Hazardous Reactions: Reacts with strong oxidizing or reducing agents, may generate heat or toxic gases
Conditions to Avoid: Extreme temperatures, moisture, direct UV radiation, incompatible material contact
Incompatible Materials: Acid chlorides, strong acids, alkali metals, strong oxidizers/reducers
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, incompletely characterized organic vapors at high temperature
Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: Oral LD50 in rodents not established, anticipated low toxicity based on structure and vitro assays, avoid deliberate ingestion
Skin Corrosion/Irritation: May cause local redness and mild discomfort, prompt washing resolves symptoms
Eye Damage/Irritation: May cause stinging or redness, prolonged contact not recommended
Respiratory Sensitization: Not recognized as a sensitizer in animal or cell studies
Germ Cell Mutagenicity: No mutagenic effects expected based on limited data, prudent care still required
Reproductive Toxicity: No evidence available; insufficient testing for chronic effect evaluation
Carcinogenicity: Not classified as carcinogen by IARC, ACGIH, NTP, or OSHA
Repeated Dose Toxicity: Not anticipated with proper lab controls, avoid chronic contact, monitor for allergic response
Medical Conditions Aggravated: Individuals with skin, eye, or respiratory conditions may exhibit increased irritation
Ecotoxicity: Not acutely toxic to aquatic or terrestrial life in dilute solutions, but avoid direct release into environment
Persistence and Degradability: Expected to be slowly biodegradable, environmental fate not fully characterized
Bioaccumulation Potential: Low, does not persist in higher trophic levels based on predicted log Kow
Soil Mobility: Moderate water solubility suggests potential mobility, do not apply to soil or drains
Other Adverse Effects: No long-term ecosystem studies available, exercise caution in case of unintended spills or emissions
Waste Disposal: Dispose according to local, regional, national regulations, send waste to permitted hazardous waste incinerator or licensed waste contractor for chemical disposal
Container Disposal: Thoroughly rinse, triple rinse containers before reuse or disposal, destroy labels and lids to prevent reuse, follow community protocols
Additional Instructions: Do not discharge wash solutions or residues into waterways, sewers, or natural environments
UN Number: Not regulated for transport by road, air, or sea (consult most recent DOT, IATA, IMDG regulations for laboratory chemicals)
Proper Shipping Name: Chemical substance, non-hazardous unless transported in larger industrial quantities
Transport Hazard Class: Does not meet criteria for DOT Hazard Classification
Packing Group: Not assigned
Environmental Hazards: None classified under transport provisions
Special Precautions: Ship in closed, labeled containers, maintain documentation and security during transit
TSCA Status: Listed or exempt
SARA Title III Sections 302/304/311/312/313: Not listed as an extremely hazardous substance
OSHA Status: Not classified as hazardous
WHMIS (Canada): Not controlled under WHMIS criteria
REACH (EU): Not listed on Candidate List, consult ECHA for updates
California Proposition 65: Not listed as a known carcinogen, reproductive, or developmental toxicant
Other Labeling Requirements: Chemical should be labeled according to workplace hazard standards, not for food, drug, or cosmetic use, keep out of reach of unauthorized personnel
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