Product Name: d-(-)-Tartaric acid diisopropyl ester
Chemical Name: Diisopropyl (2R,3R)-2,3-dihydroxysuccinate
Synonyms: Tartaric acid, diisopropyl ester; (R,R)-Diisopropyl tartrate
CAS Number: 2217-15-4
Molecular Formula: C10H18O6
Recommended Use: Intermediate in organic synthesis, chiral resolving agent in pharmaceuticals, fine chemicals manufacturing
Supplier/Manufacturer: Provide supplier’s details including address, contact phone, emergency contact number
Emergency Phone Number: Consult local regulations and site practices for chemical emergencies
UN Number: Not regulated for transport under most systems
GHS Classification: Not considered hazardous under OSHA HCS (US), EU CLP, or similar standard regulatory schemes
Label Elements: No pictogram required
Signal Word: No signal word required
Hazard Statements: May cause mild eye or skin irritation; avoid ingestion and inhalation of vapors, powders or mists
Precautionary Statements: Prevent contact with eyes, skin, and clothing. Ensure proper ventilation. Avoid breathing dust, vapors, or mist. Practice good hygiene—thoroughly wash after handling
Other Hazards: No evidence of carcinogenic, mutagenic, or reproductive risk from published data. Potential slip hazard when spilled
Chemical: d-(-)-Tartaric acid diisopropyl ester
Concentration: >99% (typical for reagent or industrial grade)
CAS Number: 2217-15-4
Impurities: Less than 1% residual solvents, water, or related organic esters possible depending on synthesis route; consult batch-specific certificate of analysis
Eye Contact: Rinse immediately with plenty of running water for several minutes; remove contact lenses if present and easy to do; seek medical attention if irritation persists
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing and wash before reuse; seek medical advice if symptoms develop
Inhalation: Move individual to fresh air; consult physician if breathing is difficult or symptoms persist
Ingestion: Rinse mouth thoroughly; give water to drink if conscious; do not induce vomiting unless directed by medical personnel; seek immediate medical attention if symptoms occur
Most Important Symptoms: Mild irritation of eyes, skin, airways or gastrointestinal tract; headaches or dizziness if large amounts inhaled or ingested
Advice to Physician: Treat symptoms; no specific antidote; supportive care as needed
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical, carbon dioxide, or water mist; avoid full water jet
Unsuitable Extinguishing Media: High-pressure water jets can spread spilled material
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, possibly irritating fumes under fire conditions
Specific Hazards: Product is a combustible liquid; vapors may form explosive mixtures with air at high temperature
Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing
Firefighting Instructions: Cool closed containers exposed to fire with water spray
Personal Precautions: Wear gloves, eye protection, and appropriate respirator if dust, vapor, or aerosol is generated; remove ignition sources from area
Environmental Precautions: Prevent material from entering drains, surface water, or soil; contain spills using sand, earth, or inert absorbent
Cleanup Methods: Absorb with inert material and collect for disposal; ventilate area and wash spill area with water; dispose of according to local and federal guidelines
Handling: Avoid contact with skin, eyes, and clothing. Use only with adequate ventilation. Wear personal protective equipment as required for laboratory or industrial work.
Storage: Keep container tightly closed in dry, cool, and well-ventilated area. Store away from incompatible materials such as strong oxidizers, acids, or bases. Protect from direct sunlight and sources of heat.
Special Storage Considerations: Store in original container; keep away from food, drink, and animal feed. Follow all safety signage and storage protocols for flammable or combustible materials if large amounts are present.
Occupational Exposure Limits: No established ACGIH, NIOSH, or OSHA exposure limits for this substance
Engineering Controls: Use fume hood in laboratory environments or provide local exhaust ventilation for bulk processing
Personal Protective Equipment:
Appearance: Clear, colorless to pale yellow liquid
Odor: Faint, ester-like
Odor Threshold: Not established
pH: Not applicable (neat liquid)
Melting Point: Approx. -10 °C
Boiling Point: 140–145 °C at 13 mmHg
Flash Point: >110 °C (closed cup)
Evaporation Rate: Not established
Flammability: Combustible liquid
Vapor Pressure: Very low at 20 °C
Vapor Density: Heavier than air
Relative Density: Approx. 1.14 g/cm³ at 20 °C
Solubility: Insoluble in water; miscible with most organic solvents
Partition Coefficient (log Kow): Not determined
Viscosity: Not established
Decomposition Temperature: No specific data; decomposes upon strong heating
Auto-ignition Temperature: Not determined
Explosive Properties: Not considered explosive
Oxidizing Properties: Not oxidizing
Chemical Stability: Stable under normal ambient and anticipated storage and handling conditions
Reactivity: No dangerous reactions under indicated use and storage
Possibility of Hazardous Reactions: May react with strong oxidizing agents; no polymerization expected
Conditions to Avoid: Heat, flames, sparks, direct sunlight, high humidity
Incompatible Materials: Strong acids, bases, oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, and small quantities of organic compounds on combustion or thermal breakdown
Likely Exposure Routes: Ingestion, skin contact, inhalation
Acute Toxicity: Low acute oral and dermal toxicity based on structural features and similar esters (oral LD50 in rats >2000 mg/kg is typical for related compounds); data for specific compound limited
Skin and Eye Irritation: Mild transient irritation possible on contact
Respiratory Effects: Inhalation of vapors, mist, or dust can cause mild irritation to airways
Chronic Exposure: No reports or evidence of chronic toxicity, carcinogenicity, mutagenicity, or reproductive toxicity
Sensitization: Not expected to be a sensitizer
Other Effects: No significant systemic health hazards documented in available literature for tartaric acid esters
Ecotoxicity: No data available for this compound; related tartaric acid esters have low toxicity to aquatic organisms
Persistence and Degradability: Readily biodegradable in the environment, breaks down into naturally occurring substances
Bioaccumulative Potential: No potential for bioaccumulation anticipated based on chemical structure and physicochemical properties
Mobility in Soil: Expected to have low mobility due to limited water solubility
Other Adverse Effects: Avoid release into waterways; material is not classified as hazardous to the environment on the basis of available data
Waste Disposal Method: Dispose of material according to federal, local, and state laws. Incinerate or landfill at approved facilities. Avoid discharge into drains or environment.
Container Disposal: Triple-rinse empty containers and send for recycling or disposal as hazardous chemical waste
Precautions: Consult licensed waste disposal contractor; follow site and regional waste treatment procedures
UN Number: Not regulated for ground, air, or marine transport
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Environmental Hazards: Not marine pollutant
Special Precautions: Protect from physical damage and excessive heat during transport. Label in accordance with chemical safety requirements for workplace, not transport.
OSHA: Not hazardous under OSHA Hazard Communication Standard
TSCA: Listed or exempt under TSCA (US)
EU REACH: Registered or pre-registered as intermediate; not classified as hazardous
Inventory Listings: Listed on EINECS, DSL, AICS, ENCS, or equivalent
SARA Title III: Not listed as extremely hazardous or toxic chemical
Other National/International Regulations: Check local, regional, and country-specific chemical safety regulations for compliance
Label Requirements: No pictograms required; hazard communication follows standard chemical hygiene protocols
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