MSDS for D(-)-DMAE Bitartrate

Identification

Product Name: D(-)-Dimethylaminoethanol Bitartrate
Synonyms: D(-)-DMAE Bitartrate
Chemical Formula: C6H15NO7
CAS Number: 5981-44-4
Recommended Uses: Laboratory research, chemical synthesis, possible use in dietary supplement raw material manufacturing processes
Supplier Information: Manufacturer or distributor contact details available upon request, including phone numbers for emergency and general queries
Emergency Contact: Emergency telephone number found on shipping documents and safety signage relevant to the workplace

Hazard Identification

GHS Classification: Not classified as a hazardous substance under GHS criteria, but handle with care due to possible irritation
Primary Hazards: Potential for eye, skin, and respiratory tract irritation, ingestion can lead to gastrointestinal discomfort
Pictograms: No GHS hazard pictogram assigned, but use precautionary icons if product handled in bulk or with high frequency
Signal Word: Caution
Hazard Statements: Contact with eyes, skin, or inhaled dust can trigger minor reactions, avoid long or repeated exposure
Precautionary Statements: Keep away from children, do not inhale powder or dust, avoid direct contact

Composition / Information on Ingredients

Chemical Name: D(-)-Dimethylaminoethanol Bitartrate
Common Name: DMAE Bitartrate
Purity: Typically ≥98% pure
Impurities: Trace water, tartaric acid, process residues <2%
Other Additives: Not typically present in USP/BP grade product

First Aid Measures

Inhalation: Remove from exposure, provide fresh air, supply oxygen if breathing is difficult, seek medical attention for persistent symptoms
Skin Contact: Wash skin immediately with plenty of water and mild soap, remove contaminated clothing, consult physician if redness or irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, seek medical attention if discomfort continues
Ingestion: Rinse mouth, do not induce vomiting, drink water to dilute, seek medical advice especially for large quantities or persistent discomfort
Acute Symptoms: Respiratory tract, skin, and eye irritation; gastrointestinal disturbance possible on ingestion
Medical Attention: Symptomatic treatment, observe for delayed effects based on individual sensitivities

Fire-Fighting Measures

Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, or water spray—choose agent based on surrounding materials
Unsuitable Media: Direct water stream may spread dust
Hazards from Combustion: Thermal decomposition can create carbon oxides, nitrogen oxides, irritating or toxic fumes
Protective Equipment: Wear self-contained breathing apparatus and full protective gear to limit exposure to smoke and fumes
Special Precautions: Keep containers cool by spraying with water to avoid explosion, fight fire from upwind position

Accidental Release Measures

Personal Precautions: Evacuate area if dust clouds form, avoid breathing dust, ventilate area, use appropriate personal protective gear
Environmental Precautions: Prevent powder from entering drains or surface waters, alert local authorities if large spills threaten waterways
Cleanup Methods: Sweep up spilled material with minimal dust creation, use vacuum with HEPA filter if available, wash spill site with water after complete cleanup
Waste Disposal: Collect contaminated materials in suitable containers for proper disposal according to local regulations

Handling and Storage

Handling: Use in well-ventilated areas, avoid raising dust, wash hands after handling, avoid contact with eyes, skin, and clothing
Equipment Notes: Ground and bond containers for transfer, use tools that do not produce sparks
Storage: Keep in tightly closed container, store away from incompatible materials like strong oxidizers, acids, and bases, protect from moisture and direct sunlight
Temperature Requirements: Store at room temperature in a dry, cool, ventilated area
Shelf Life: Maintain original packaging integrity and label legibility for product tracking

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established ACGIH, OSHA, or NIOSH limits, but minimize exposure by best available control methods
Engineering Controls: Use local exhaust or process enclosure if dust generated, monitor for airborne levels periodically
Respiratory Protection: NIOSH-approved particulate mask if exposure risk exists, avoid inhalation
Eye Protection: Safety goggles with side shields recommended for laboratory and bulk handling
Skin Protection: Wear suitable gloves, lab coat, and closed footwear to prevent prolonged exposure
Hygiene Measures: Wash thoroughly after handling, avoid eating, drinking, or smoking in areas where the chemical is used or stored

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Slightly fishy or amine-like
pH (1% solution): Slightly acidic, typically 3–4
Melting Point: Approximately 132–138 °C
Boiling Point: Decomposes before boiling
Solubility: Readily soluble in water, partially soluble in ethanol
Density: Around 1.5 g/cm³
Vapor Pressure: Not applicable (solid at room temperature)
Flash Point: Not applicable
Partition Coefficient: Data not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions, avoid excess moisture to prevent decomposition
Incompatible Materials: Strong acids, oxidizing agents, strong bases can trigger unwanted chemical reactions
Hazardous Decomposition: Produces carbon oxides, nitrogen oxides, and possibly low molecular weight organic compounds upon decomposition
Polymerization: Not known to undergo hazardous polymerization
Reactivity: Low as supplied, but take care to avoid contact with incompatible chemicals

Toxicological Information

Acute Toxicity: Oral LD50 (rat) typically exceeds 2000 mg/kg, not considered acutely toxic at routine exposure levels
Skin Corrosion/Irritation: May cause mild irritation, especially with prolonged or repeated contact
Eye Damage/Irritation: May produce redness, watering, discomfort if splashed in the eyes, always rinse immediately
Respiratory Sensitization: Dust inhalation can irritate airways, provide adequate ventilation during bulk handling
Chronic Toxicity: No comprehensive long-term exposure studies, practice caution and avoid unnecessary chronic exposure
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No current data indicating reproductive effects at regulated exposure limits

Ecological Information

Ecotoxicology: Data limited, expected to have low toxicity to aquatic and terrestrial organisms based on chemical structure
Persistence/Degradability: Readily biodegradable in natural settings, does not persist significantly in soil or water
Bioaccumulation: Unlikely to bioaccumulate due to its high solubility and metabolic breakdown
Mobility: Highly soluble, potential for movement through soil and water if released in large quantities
Other Adverse Effects: Avoid uncontrolled releases, proper disposal reduces environmental risk

Disposal Considerations

Waste Methods: Dispose of material in accordance with local, regional, and national laws, incineration or chemical treatment for hazardous waste sites
Packaging Disposal: Empty containers retain product residues, treat as hazardous waste and follow label disposal instructions
Precautions: Keep out of landfills or municipal drains that could contaminate waterways, separate incompatible waste streams to reduce chemical reactivity at disposal

Transport Information

UN Number: Not regulated for transport under ADR, RID, DOT, or IMDG
Transport Hazard Class: Not classified as dangerous goods
Packing Group: No designation
Label Requirements: Use standard chemical labeling including product name, cautionary statements, and emergency phone number
Special Precautions: Secure containers to prevent breakage, avoid temperature extremes, and segregate from incompatible substances

Regulatory Information

OSHA Status: Not regulated as a hazardous substance under OSHA Hazard Communication Standard
TSCA Status: Listed in the United States Toxic Substances Control Act Inventory
EU Regulations: Not classified under the EU Regulation (EC) No 1272/2008 (CLP)
Other: Product and workplace exposure should still be controlled by standard best practices, avoid discharge into the environment without proper treatment, report adverse spills according to mandatory governmental requirements