Material Safety Data Sheet (MSDS) for D-(-)-Di-O-benzoyltartaric Acid

Identification

Product Name: D-(-)-Di-O-benzoyltartaric acid
Chemical Formula: C18H14O8
CAS Number: 2743-38-6
Synonyms: D-Dibenzoyl Tartaric Acid, DDBTA
Use: Chiral resolving agent, chemical intermediate for pharmaceuticals
Manufacturer Information: Request specific supplier details for emergency contacts and guidance
Emergency Phone Number: Refer to local supplier listing
Recommended Restrictions: Laboratory and chemical synthesis use only

Hazard Identification

GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2)
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation
Precautionary Statements: Avoid contact with skin and eyes, wear protective gloves and eye protection
Pictograms: Exclamation mark
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Effects of Exposure: Irritation of skin, eyes, and respiratory tract; symptoms may include itching, redness, and discomfort

Composition / Information on Ingredients

Chemical Name: D-(-)-Di-O-benzoyltartaric acid
Common Name: DDBTA
Purity: ≥98%
CAS Number: 2743-38-6
Impurities: Typically contains less than 2% unidentified ingredients based on supplier documentation
Molecular Weight: 358.30 g/mol

First Aid Measures

Inhalation: Move affected person to fresh air, keep comfortable for breathing, seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing, wash affected skin with soap and water, seek medical attention if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, seek prompt medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice if feeling unwell
Self-Protection of First Aiders: Use gloves and safety glasses before offering assistance to the affected individual

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Do not use water jet directly on burning chemical
Specific Hazards: Combustion produces toxic and irritating gases, including carbon oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective clothing
Special Firefighting Procedures: Use water spray to cool exposed containers, prevent runoff into drains

Accidental Release Measures

Personal Precautions: Wear protective gloves, goggles, and lab coat, avoid contact with skin and eyes
Environmental Precautions: Prevent entry into drains, sewers, and surface water
Cleanup Methods: Scoop up spilled material, transfer to closed container for disposal, ventilate area, clean surface with water and cleaning agent
Removal of Residues: Absorb with inert material like sand, wash area with copious amounts of water

Handling and Storage

Handling: Work in a well-ventilated area, avoid dust formation, avoid contact with skin, eyes, and clothing
Hygiene Practices: Wash hands thoroughly after handling, remove contaminated clothing and wash before reuse
Storage Conditions: Store in tightly closed original container, keep in a cool, dry, well-ventilated area, protect from light and moisture
Incompatible Materials: Bases, strong oxidizers, strong reducing agents

Exposure Controls and Personal Protection

Engineering Controls: Use chemical fume hood or local exhaust ventilation to control exposure
Personal Protective Equipment: Wear safety glasses with side shields, laboratory gloves, and protective clothing
Respiratory Protection: Use approved dust mask or respirator if dust or airborne particulates are generated
Hand Protection: Chemical-resistant gloves recommended
Eye Protection: Chemical safety goggles
Environmental Controls: Avoid release to the environment, contain spill to prevent spread

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: 194 – 198°C (381 – 388°F)
Boiling Point: Data not available
Solubility: Very slightly soluble in water, soluble in ethanol and organic solvents
pH: Not applicable (solid)
Relative Density: Approximately 1.5 g/cm³
Vapor Pressure: Negligible at room temperature
Partition Coefficient: Not available
Decomposition Temperature: Above 200°C releases benzoyl compounds

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Non-reactive under normal laboratory conditions
Hazardous Reactions: Not expected to undergo hazardous reactions in recommended conditions
Conditions to Avoid: Heating above decomposition temperature, moisture, exposure to strong acids or bases
Incompatible Materials: Strong oxidizers, strong bases, strong acids
Hazardous Decomposition: Produces carbon monoxide, carbon dioxide, benzoyl compounds under fire or decomposition

Toxicological Information

Likely Routes of Exposure: Skin and eye contact, inhalation, ingestion
Acute Toxicity: Not classified as acutely toxic, limited data in humans, can cause irritation to mucous membranes
Chronic Effects: No evidence of long-term health effects when handled with care
Skin Corrosion/Irritation: Causes moderate irritation based on similar organic acids
Serious Eye Damage/Irritation: Causes eye irritation
Sensitization: Not reported to cause respiratory or skin sensitization
Reproductive Toxicity: No available data suggests direct reproductive effects
Carcinogenicity: Not listed by IARC, NTP, or OSHA as carcinogenic

Ecological Information

Ecotoxicity: No standardized test data available, based on structure, at significant release levels could pose risk to aquatic organisms
Persistence and Degradability: Expected to be slowly biodegradable
Bioaccumulative Potential: Not expected to significantly bioaccumulate due to low solubility in water
Mobility in Soil: Low mobility anticipated, substance binds to soil organic matter
Other Adverse Effects: Prevent release to the environment, especially water bodies

Disposal Considerations

Disposal Methods: Collect and supply waste for proper disposal in accordance with local, regional, and national regulations
Packaging Disposal: Contaminated packaging should be disposed of in the same manner as product
Special Precautions: Do not discharge to sewers or watersheds, neutralize residue before disposal if required by local rules

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not regulated under most international transport guidelines
Transport Hazard Class: Not classified
Packing Group: Not classified
Marine Pollutant: No
Special Transport Considerations: Always protect from physical damage and moisture during transport, ensure proper labeling on containers

Regulatory Information

International Inventories: Listed in some national inventories, check country-specific regulations for status
OSHA Hazard Communication Standard: Considered hazardous based on irritation potential
REACH Registration: Components may require notification, always verify compliance
TSCA: Appears on the inventory
Other Regulations: Not subject to specific restrictions, general chemical handling principles from workplace safety laws apply, adhere to local and national provisions for workplace safety, proper labeling, and emergency response procedures