Material Safety Data Sheet for D(-)CHOLINE BITARTRATE

1. Identification

Product Name: D(-)Choline Bitartrate
Chemical Name: (2-Hydroxyethyl)trimethylammonium bitartrate
CAS Number: 87-67-2
Synonyms: Choline hydrogen tartrate, Choline bitartrate, Vitamin B4 salt
Manufacturer: Supplier contact information available on request
Recommended Use: Nutritional supplement, laboratory reagent
Restrictions on Use: Not intended for pharmaceutical applications or direct human consumption without assessment

2. Hazard Identification

Classification: Not classified as hazardous under GHS criteria
Label Elements: No pictogram or signal word required
Hazard Statements: May cause mild irritation if inhaled, swallowed, or in contact with eyes or skin
Precautionary Statements: Avoid breathing dust, wash thoroughly after handling, store in a closed container
Other Hazards: Finely divided powder can form explosive dust/air mixtures
Route of Exposure: Inhalation, ingestion, skin and eye contact

3. Composition / Information on Ingredients

Chemical Identity: D(-)Choline Bitartrate
CAS Number: 87-67-2
EINECS Number: 201-763-4
Purity: Greater than 98%
Impurities: No relevant hazardous impurities present
Molecular Formula: C9H19NO7
Molecular Weight: 253.25 g/mol

4. First Aid Measures

Inhalation: Move to fresh air. Seek medical attention if symptoms such as coughing or difficulty breathing occur.
Skin Contact: Remove contaminated clothing. Rinse skin thoroughly with water. Get medical help if irritation develops.
Eye Contact: Flush eyes immediately with plenty of water for at least 15 minutes. Seek medical attention if redness or pain persists.
Ingestion: Rinse mouth with water, do not induce vomiting. Seek medical attention if symptoms appear.
Most Important Symptoms: Mild respiratory, skin, or eye irritation
Notes to Physician: Treat symptomatically

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, or foam
Unsuitable Extinguishing Media: Do not use full water jet on burning powder
Specific Hazards: May produce hazardous decomposition gases such as carbon oxides, nitrogen oxides under fire
Protective Equipment: Firefighters wear self-contained breathing apparatus and protective gear
Fire/Explosion Risks: Dust may form explosive mixture in air
Special Procedures: Avoid raising dust, use water spray to cool containers exposed to fire

6. Accidental Release Measures

Personal Precautions: Wear protective clothing, gloves, and eye protection. Avoid dust formation.
Environmental Precautions: Prevent entry into drains, surface and groundwaters
Containment Methods: Cover powder spill, avoid creating airborne dust
Cleanup Procedures: Sweep up gently, place in a labeled, tightly closed waste container
Decontamination: Wash area with water after cleanup
Disposal: Dispose of in accordance with local, regional and national regulations

7. Handling and Storage

Safe Handling: Use only in well-ventilated areas. Avoid breathing dust or contact with eyes and skin.
Handling Precautions: Wear appropriate PPE, wash hands thoroughly after handling
Storage Conditions: Store in original container, tightly closed, in a cool, dry, well-ventilated area away from incompatible substances
Incompatibilities: Avoid storage with strong oxidizers or strong acids
Specific Storage Requirements: Protect from moisture and direct sunlight

8. Exposure Controls and Personal Protection

Exposure Limit Values: No established occupational exposure limits
Engineering Controls: Provide adequate ventilation, use local exhaust if necessary
Eye Protection: Safety goggles or face shield
Skin Protection: Chemical resistant gloves and lab coat
Respiratory Protection: Dust mask or respirator if dust is generated
Hygiene Measures: Wash hands after handling, keep work area clean

9. Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH (5% solution): 3.5–5.5
Melting Point/Freezing Point: 151–152°C (decomposes)
Solubility in Water: Very soluble
Solubility in Other Solvents: Slightly soluble in ethanol
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not applicable
Evaporation Rate: Not available
Vapor Pressure: Not relevant
Vapor Density: Not relevant
Relative Density: 1.2 g/cm3
Partition Coefficient (n-octanol/water): Not available
Autoignition Temperature: Not determined
Explosive Properties: Dust may form explosive mixtures in air
Oxidizing Properties: Not classified as an oxidizer

10. Stability and Reactivity

Chemical Stability: Stable under recommended conditions of use and storage
Reactivity: Not reactive under normal conditions
Conditions to Avoid: Excessive heat, open flame, strong oxidizers
Incompatible Materials: Strong acids, strong oxidizers
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides
Hazardous Polymerization: Will not occur
Other Stability Issues: Absorbs moisture from air

11. Toxicological Information

Acute Toxicity: Low toxicity based on available data
LD50 (oral, rat): >5000 mg/kg
Skin Corrosion/Irritation: May cause mild irritation on prolonged contact
Serious Eye Damage/Irritation: May cause mild irritation
Respiratory or Skin Sensitization: No data suggesting sensitization
Germ Cell Mutagenicity: No evidence of mutagenicity
Carcinogenicity: Not listed by IARC, NTP, OSHA
Reproductive Toxicity: No data indicating hazard
Specific Target Organ Toxicity – Single Exposure: Not classified
Specific Target Organ Toxicity – Repeated Exposure: Not classified
Aspiration Hazard: Not expected

12. Ecological Information

Ecotoxicity: Expected to have minimal environmental impact, not classified as hazardous
Aquatic Toxicity: Not considered toxic to aquatic organisms at standard concentrations
Persistence and Degradability: Readily biodegradable
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: Likely to be mobile due to high solubility in water
Other Adverse Effects: Limited data available, no evidence for significant environmental persistence or harm

13. Disposal Considerations

Disposal Methods: Dispose of surplus and non-recyclable solutions to approved waste disposal facility
Contaminated Packaging: Empty containers must be triple rinsed and disposed according to local regulations
Special Precautions: Avoid release into environment, do not dispose of in drains
Legal Requirements: Disposal subject to national and regional regulations

14. Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Not applicable
Transport in Bulk: Not applicable
Special Precautions for User: Avoid generating dust during handling and transport

15. Regulatory Information

Safety, Health and Environmental Regulations: Not subject to specific regulatory requirements under OSHA, TSCA, DSL, EINECS
GHS Labeling: No specific labeling required
SARA Title III: Not listed
California Proposition 65: Not listed
REACH Status: Meets criteria as non-hazardous component
Workplace Hazardous Materials Information System (WHMIS): Not controlled
Other Regulatory Listings: Check local, regional, and national inventories for compliance