Product Name: Chromium Gluconate
Chemical Family: Chromium(III) Salt of Gluconic Acid
Synonyms: Chromium(III) gluconate, Chromium hexahydroxyhexanoate
CAS Number: 527-09-3
Molecular Formula: C12H22CrO14
Recommended Use: Food supplement, nutritional additive, ingredient for vegan and vegetarian preparations
Supplier: Manufacturer/Distributor contact information typically provided on shipment document
Emergency Contact: Refer to local poison control center or manufacturer’s emergency hotline
GHS Classification: Non-hazardous under normal conditions; not classified as toxic, flammable, or reactive
Physical Hazards: None expected in normal conditions
Health Hazards: Inhalation of dust may irritate respiratory passages; persistent exposure could cause mild eye/skin irritation
Environmental Hazards: No major environmental hazards known at typical dilution; high concentrations may impact aquatic life
Label Elements: Not regulated for hazards; no specific pictograms required
Precautionary Statements: Avoid breathing dense dust; wash hands after handling; prevent release of large quantities to water sources
Chemical Name: Chromium Gluconate
Common Ingredients: Pure chromium(III) gluconate (greater than 98% by weight)
Impurities: Minor traces of unreacted gluconic acid or salts may exist, levels below 2%
Animal Origin: No animal-derived components; 100% plant-based or synthetic pathways utilized for vegan/vegetarian standards
Hazardous Components: None above regulation threshold
EINECS No.: 208-416-2
Eye Contact: Rinse gently with water for several minutes; remove contact lenses if present and easy to do; seek medical attention for persistent irritation
Skin Contact: Wash thoroughly with soap and water; seek attention if rash or irritation develops
Inhalation: Move affected person to fresh air; if symptoms such as coughing or shortness of breath persist, consult medical support
Ingestion: Rinse mouth; drink water in small sips; do not induce vomiting unless instructed; consult medical personnel if feeling unwell
Most Important Symptoms: Mild, transient eye or respiratory irritation possible from prolonged dust exposure
Note to Physician: Symptomatic treatment; no specific antidote known
Suitable Extinguishing Media: Use dry chemical powder, foam, carbon dioxide, or water spray according to surrounding fire
Unsuitable Extinguishing Media: Do not direct high-pressure water jet at substance, as it may spread settled dust
Specific Hazards Arising: High temperatures can release carbon oxides, chromium oxides, or other irritants
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Special Precautions: Move unaffected containers from danger area, cool exposed containers with water spray
Personal Precautions: Use dust mask, goggles, and gloves for cleanup; limit unnecessary personnel in affected area
Environmental Precautions: Prevent bulk amounts from entering drains, waterways or soil
Cleanup Methods: Sweep up substance without generating dust; place in labeled, closable container for proper disposal
Reference to Other Sections: Review exposure controls as described elsewhere in this document for additional safety details during cleanup
Handling: Use in a well-ventilated area; minimize creation of airborne dust
Hygiene Practices: Wash hands thoroughly after use; keep food/beverage away from work zones
Storage Conditions: Store in cool, dry, well-ventilated area away from heat sources and strong oxidizing agents
Container Requirements: Keep tightly closed in labeled original packaging
Incompatible Materials: Avoid contact with strong acids, alkalis, potent oxidizing materials
Shelf Life: Typically stable under recommended storage conditions for up to three years
Exposure Limits: No established occupational exposure limits for chromium gluconate; analogs suggest controlling airborne dust below nuisance particulate levels (generally 10 mg/m³)
Engineering Controls: Use local exhaust ventilation or respiratory protection in dusty conditions
Respiratory Protection: NIOSH-approved dust mask or particulate respirator if airborne particles become bothersome
Eye Protection: Chemical safety goggles or safety glasses
Skin Protection: Impervious gloves if handling bulk powder; work clothing to minimize skin contact
Additional Hygiene Measures: Facilities for quick drenching or flushing of the eyes and skin should be available in the work area
Appearance: Fine, light green to grayish powder
Odor: Odorless or faint sweet odor
pH (solution): Approximately 5.5 - 7.5 (1% aqueous solution)
Melting Point: Decomposes before melting
Boiling Point: Not applicable (decomposes prior to boiling)
Solubility: Freely soluble in water, insoluble in most organic solvents
Vapor Pressure: Not volatile
Density: Approximately 1.65 g/cm³
Partition coefficient (n-octanol/water): Not available
Evaporation Rate: Not applicable
Flash Point: Not flammable
Autoignition Temperature: Not self-heating
Chemical Stability: Stable under recommended storage and handling conditions
Possible Hazardous Reactions: No hazardous polymerization
Conditions to Avoid: Excessive heat, exposure to strong acids, alkalis, and oxidizing agents
Incompatible Materials: Strong oxidizers (may react vigorously), mineral acids (may cause decomposition)
Decomposition Products: Thermal breakdown can generate carbon oxides (CO, CO₂) and chromium oxides in high temperature fires
Acute Toxicity: Low acute oral toxicity, LD50 in rats reported as higher than 2000 mg/kg
Chronic Effects: No significant effects in repeated dietary studies at nutritional levels; excess dosing may affect glucose metabolism
Potential Routes of Exposure: Oral ingestion, inhalation of dust, skin and eye contact
Symptoms: May cause slight skin, eye, or respiratory discomfort at high doses or frequent exposure
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA; trivalent chromium compounds generally recognized as low risk
Mutagenicity/Reproductive Effects: No evidence in standard studies
Sensitization: Not expected to cause allergic reactions
Acute Aquatic Toxicity: Not expected to pose hazard at typical dilutions; high concentrations could lead to mild local water body contamination
Persistence and Degradability: Readily biodegradable based on gluconate content; chromium(III) is relatively immobile and minimally bioavailable
Bioaccumulation Potential: Low likelihood due to mineral character and poor lipid solubility
Mobility in Soil: Poorly mobile, chromium remains bound in insoluble trivalent state
Other Adverse Effects: None anticipated if used/disposed according to recommended practice
Waste Disposal Guidance: Dispose in compliance with local, regional, and national regulations
Recommended Methods: Landfill or incineration in authorized facilities; avoid uncontrolled release to environment
Container Disposal: Triple-rinse, puncture/drain, and recycle where possible
Clean-Up Materials: Sweep powder residues into suitable containers, label for chemical waste collection
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as dangerous goods by ICAO/IATA, IMDG, or DOT
Packing Group: Not assigned
Hazard Class: Non-hazardous, not restricted in transit
Special Transportation Measures: Protect from excessive moisture and physical damage; avoid spillage during loading/unloading
OSHA Status: Not hazardous under US OSHA Hazard Communication Standard
TSCA (Toxic Substances Control Act): Chromium gluconate listed or eligible for listing
SARA Title III: Does not contain chemicals listed as extremely hazardous substances
California Proposition 65: Product does not contain materials known to the State of California to cause cancer or reproductive toxicity
EU REACH: Not classified for restrictions; meets safety obligations for non-hazardous compounds
Food Additive Status: Permitted for dietary use within prescribed limits in US, EU, and several ASEAN countries
Vegan/Vegetarian Compliance: Certified free from animal products; suitable for all dietary uses without risk of cross-contamination
Other International Regulations: Fulfills safety requirements in Canada, Australia, and Japan for non-hazardous nutritional additives
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