Material Safety Data Sheet: Chromium D-Gluconate (Vegan/Vegetarian)

Identification

Product Name: Chromium D-Gluconate
Chemical Family: Organometallic Salt
Molecular Formula: C12H22CrO14
Synonyms: Chromium(III) gluconate, Chromium(III) D-gluconate
Use of Substance: Dietary supplement ingredient, nutritional products, food fortification
Manufacturer: Plant-based nutritional suppliers
Emergency Contact Number: Refer to relevant poison control or manufacturer-specific hotline
CAS Number: 527-09-3

Hazard Identification

GHS Classification: Not classified as hazardous under applicable GHS criteria
Signal Word: None
Hazard Statements: Product may cause mild irritation to eyes, skin, and respiratory tract in sensitive individuals;
Precautionary Statements: Avoid dust formation; Use only in well-ventilated areas; Wash hands after handling
Health Hazards: Prolonged exposure can contribute to headache, mild respiratory discomfort or cough
Environmental Hazards: Large spills may increase chromium levels in aquatic systems shaking up local balance

Composition / Information on Ingredients

Ingredient: Chromium D-Gluconate
Chemical Name: Chromium(III) D-gluconate
Content (%): 98–100%
Impurities: Trace metals below food-grade limits; Confirm absence of animal byproducts for vegan/vegetarian status
CAS Number: 527-09-3
EC Number: 208-392-1

First Aid Measures

Inhalation: Move to fresh air; Seek medical attention for persistent coughing or shortness of breath
Eye Contact: Rinse eyes under running water for at least 15 minutes; If redness or itching develops, get medical help
Skin Contact: Wash affected area with soap and water; Remove any contaminated clothing
Ingestion: Rinse mouth with water; Do not induce vomiting; Seek medical advice if large amounts are swallowed or discomfort occurs
Most important symptoms and effects: Minor irritation, gastrointestinal upset in rare cases

Fire-Fighting Measures

Suitable Extinguishing Agents: Use water spray, foam, dry chemical, or carbon dioxide for surrounding fire
Specific Hazards: Product does not readily burn; During combustion, may emit fumes containing chromium oxides
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Thermal Decomposition Products: Carbon oxides, chromium compounds
Explosion Hazards: No known risks under normal conditions

Accidental Release Measures

Personal Precautions: Avoid dust inhalation; Wear gloves, goggles, and dust mask
Environmental Precautions: Prevent material from reaching soil, drains, or watercourses
Containment Methods: Sweep up gently to avoid dust clouds; Use only clean, dry tools
Cleanup Procedures: Transfer residue into suitable containers for disposal; Ventilate area after removal

Handling and Storage

Handling: Minimize dust generation; Do not eat, drink, or smoke during handling; Wash thoroughly after use
Safe Storage Conditions: Store in cool, dry, well-ventilated place away from strong acids or bases; Keep container tightly closed
Incompatible Materials: Strong oxidizers and reducing agents
Special Precautions: Use dedicated utensils and equipment to avoid cross-contamination with non-vegan products

Exposure Controls and Personal Protection

Engineering Controls: Local ventilation or general dilution ventilation if dust arises
Personal Protection: Safety glasses, lab coats, nitrile or latex gloves
Respiratory Protection: Approved particulate respirators for handling large quantities
Skin Protection: Protective gloves and long-sleeved clothing
Hygiene Measures: Wash hands before breaks and after finishing the workday; No food or drink near handling area

Physical and Chemical Properties

Appearance: Fine, off-white to pale-green powder
Odor: Odorless
Odor Threshold: Not applicable
pH (1% solution): 6.5–8.5
Melting Point: Not available
Boiling Point: Not relevant; decomposes before boiling
Solubility in Water: Freely soluble
Vapor Pressure: Negligible
Density: 1.6–1.8 g/cm³
Flash Point: Not applicable
Explosive Properties: None
Oxidizing Properties: None

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures
Reactivity: Reacts with strong acids, bases, and oxidizers
Conditions to Avoid: Excessive heat, open flame, moisture
Incompatible Materials: Strong oxidizing agents, strong reducing agents
Hazardous Decomposition Products: Carbon oxides, chromium oxides
Polymerization: Will not occur

Toxicological Information

Acute Toxicity: Low--typical LD50 (oral, rat) above 5000 mg/kg
Chronic Effects: Dietary levels of trivalent chromium considered safe; Excess intake over long term may influence kidney or liver function
Irritation: Mild skin, eye, or respiratory irritation in rare cases
Sensitization: No confirmed reports in humans of allergenic responses
Carcinogenicity: No evidence for trivalent chromium compounds as carcinogens per IARC or OSHA
Reproductive Toxicity: No observed adverse effects in reproductive screening studies; Avoid high levels if pregnant unless prescribed

Ecological Information

Aquatic Toxicity: Low; large spills can increase localized chromium concentrations and influence aquatic ecosystems
Persistence and Degradability: Compound slowly breaks down through natural biological processes
Bioaccumulation: Unlikely under normal conditions due to moderate solubility and stability
Mobility in Soil: Moderate mobility; potential leaching in sandy soils
Other Adverse Effects: Monitor for potential impact in sensitive or protected habitats

Disposal Considerations

Waste Disposal Methods: Follow local, regional, and national regulations. Dispose via incineration or secure landfill for non-hazardous organic chemicals
Container Disposal: Clean thoroughly before recycling or disposal; Avoid reuse for food or animal products
Special Precautions: Do not release large amounts to environment; Avoid drains and waterways

Transport Information

UN Number: Not regulated
Shipping Name: Chromium D-Gluconate
Transport Hazard Class: Non-hazardous for air, road, rail, sea
Packing Group: Not applicable
Special Precautions: Keep containers sealed, dry, and upright during transport; Protect from moisture and heat

Regulatory Information

Labeling Requirements: Not classified as hazardous; standard nutritional labeling for dietary use
Inventory Status: Listed on most regulatory inventories including EU, US (TSCA), Canada (DSL/NDSL), Australia (AICS)
Food Safety Regulations: Meets standards for vegan/vegetarian products under food safety guidelines; Chromium intake should comply with dietary reference values
Workplace Safety: Not subject to specific workplace exposure limits; Follow good laboratory and manufacturing practices
Other Regulations: No applicable export restrictions; Regular ingredient analysis recommended for vegan/vegetarian certification