Material Safety Data Sheet: Choline Bitartrate

Identification

Chemical Name: Choline Bitartrate
Synonyms: L-2-Hydroxyethyltrimethylammonium hydrogen tartrate
CAS Number: 87-67-2
Recommended Use: Food additive, dietary supplement, laboratory reagent
Manufacturer/Supplier: Contact your local supplier or laboratory source
Contact Information: Emergency phone and address details provided by manufacturer
Product Code: Varies by supplier

Hazard Identification

GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 3)
Signal Word: Warning
Hazard Statements: Causes mild skin irritation; causes serious eye irritation
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, use personal protective equipment as required
Pictograms: Exclamation mark (GHS07)

Composition / Information on Ingredients

Substance: Choline Bitartrate
Chemical Formula: C9H19NO7
Molecular Weight: 253.25 g/mol
Ingredients: Choline bitartrate (≥98%), trace moisture
Impurities: Typical for food or reagent grade, consult certificates of analysis for more details

First Aid Measures

Inhalation: Move person to fresh air, seek medical advice if symptoms persist such as coughing or difficulty breathing
Skin Contact: Remove contaminated clothing, wash area with water and soap, seek advice with irritation or reaction
Eye Contact: Rinse gently with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek attention if irritation persists
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical help if feeling unwell or after large ingestion
Notes for Physician: Symptomatic treatment as needed, support respiratory function if exposed to powder dust in large quantities

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Unsuitable Media: Water jet can spread burning powder
Special Hazards: Emits toxic fumes under fire conditions such as carbon monoxide, carbon dioxide, nitrogen oxides
Protective Equipment: Wear full protective clothing and self-contained breathing apparatus
Fire Fighting Procedures: Contain material to avoid spread, cool exposed containers with water mist, prevent runoff to drains or water sources

Accidental Release Measures

Personal Precautions: Use personal protective clothing, avoid dust formation, prevent inhalation of powder
Environmental Precautions: Do not let product enter drains, keep out of natural water sources and soil
Spill Cleanup Methods: Use non-sparking tools, sweep up and place in a suitable container for disposal, ventilate area, wash after handling

Handling and Storage

Handling: Keep containers closed, use in well-ventilated area, avoid creating dust, avoid contact with eyes and skin
Storage Conditions: Store in cool, dry, well-ventilated area away from incompatible substances, keep container tightly sealed
Incompatible Materials: Strong oxidizers, acids, bases
Specific End Use: Handle according to standard laboratory and workplace protocols, avoid exposure to high humidity

Exposure Controls and Personal Protection

Control Parameters: No established occupational exposure limits; avoid repeated or prolonged exposure
Engineering Controls: Use local exhaust ventilation, process enclosures, or other engineering controls to keep airborne levels low
Personal Protective Equipment: Wear safety goggles to prevent eye exposure, use protective gloves and lab coat, if risk of inhalation is present, wear dust mask or respirator rated for particulates
Hygiene Measures: Wash hands before breaks and after finishing work, do not eat or drink in work area

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Very slight, often described as faintly amine
Odor Threshold: No data available
pH (5% solution): 3.5–4.5
Melting Point: Approximately 152°C (decomposes)
Boiling Point: Not applicable (decomposes)
Flash Point: Not flammable under standard conditions
Solubility: Soluble in water, slight solubility in ethanol
Partition Coefficient (n-octanol/water): No data
Vapor Pressure: Negligible at room temperature
Density: 1.4–1.5 g/cm³
Evaporation Rate: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive under typical use or storage
Hazardous Reactions: Exposure to strong oxidizing agents may cause reaction
Conditions to Avoid: Moisture, heat, sources of ignition
Decomposition Products: Carbon oxides, nitrogen oxides, choline, tartaric acid under fire or decomposing conditions

Toxicological Information

Acute Toxicity: Very low acute toxicity by oral, dermal, and inhalation routes; LD50 oral (rat) >5000 mg/kg
Skin Corrosion/Irritation: May cause mild irritation
Serious Eye Damage/Irritation: Causes eye irritation
Respiratory or Skin Sensitization: Not a skin sensitizer, inhalation of excessive dust irritates respiratory tract
Chronic Effects: No known long-term effects at low exposure; excessive consumption may cause gastrointestinal discomfort
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Not classified as carcinogenic, mutagenic, or reprotoxic based on available data
Additional Information: Allergic reactions are rare, but hypersensitive individuals should avoid ingestion or handling

Ecological Information

Ecotoxicity: Not expected to be hazardous for the environment; study data limited
Persistence and Degradability: Readily biodegradable in environment, breaks down into choline and tartaric acid
Bioaccumulative Potential: Low, not expected to bioaccumulate
Mobility in Soil: Water-soluble, likely to migrate in aqueous environments
Other Adverse Effects: None known based on standard environmental hazard assessments

Disposal Considerations

Waste Treatment Methods: Dispose of contents and container in accordance with local, regional, national, and international regulations
Product Disposal: Small quantities can be disposed in the trash or by incineration in controlled facility; larger spills collected and sent to licensed waste handler
Contaminated Packaging: Rinse and recycle where permitted, or dispose as chemical waste

Transport Information

UN Number: Not regulated for transport
UN Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions: Avoid contact with moisture, protect from physical damage during transportation

Regulatory Information

TSCA Status: Listed
EC Number: 201-763-4
REACH Status: Exempt or registered depending on use
US OSHA Classification: Not a hazardous substance
DSL/NDSL (Canada): Listed
WHMIS Classification: Not controlled
Other Information: Product complies with relevant food and chemical safety regulations in major markets if purity is suitable