Material Safety Data Sheet (MSDS): Choline Bitartrate

Identification

Substance Name: Choline Bitartrate
Chemical Formula: C9H19NO7
Synonyms: Choline Hydrogen Tartrate, Choline Salt Bitartrate
CAS Number: 87-67-2
Product Code: Specific to manufacturer batch
Recommended Use: Nutritional supplements, food additive, research
Supplier Information: Listed on container or shipment documentation
Emergency Contact: Accessible through local emergency numbers or SDS-prepared safety offices in place of purchase

Hazard Identification

Physical State: White crystalline powder
GHS Classification: Not classified as hazardous under GHS
Label Elements: No pictogram, signal word not required
Health Effects: Inhalation or ingestion may cause mild irritation such as headaches, digestive discomfort, or nose and throat irritation in sensitive individuals
Environmental Hazards: Not expected to present significant hazards in typical handling scenarios
Specific Hazards: High concentrations of airborne dust may create mild respiratory discomfort, avoid prolonged direct contact with eyes

Composition / Information on Ingredients

Main Component: Choline Bitartrate, 98-100%
Impurities: Moisture (up to 0.5%), trace elements below reporting thresholds
Chemical Family: Quaternary ammonium compounds, organic acids
Molecular Weight: 253.25 g/mol

First Aid Measures

Inhalation: Remove to fresh air, allow normal breathing, provide water. Obtain medical attention if symptoms persist.
Skin Contact: Rinse exposed skin thoroughly with running water. Remove clothing if needed.
Eye Contact: Rinse eyes gently for several minutes with clean water, keeping eyelids open.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical advice for persistent discomfort or large accidental ingestion.
Specific Symptoms: Redness or mild irritation at contact site

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, CO2 extinguishers
Unsuitable Media: Strong water jets may spread material
Specific Hazards: May release fumes of nitrogen oxides or carbon oxides under strong combustion
Protective Equipment: Wear self-contained breathing apparatus and protective clothing during fire response
Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides
Fire Fighting Instructions: Contain runoff to prevent contamination of water bodies

Accidental Release Measures

Personal Precautions: Avoid dust generation, ventilate area, wear protective mask and gloves
Environmental Precautions: Prevent release to drains, surface water, or soil. Use standard barriers as necessary
Methods for Containment: Scoop up spilled powder and place in a labeled waste container. Avoid dry sweeping to limit dust clouds
Cleanup Procedures: Use damp cloth or vacuum with HEPA filter. Dispose of cleanup materials in accordance with local regulations

Handling and Storage

Precautions for Handling: Minimize dust, avoid contact with eyes and skin, follow standard lab hygiene
Occupational Guidance: Use in well-ventilated locations, wear dust mask if aerosolization risk exists
Recommended Storage Conditions: Store in sealed, labeled containers placed in a cool, dry, and well-ventilated area
Incompatible Substances: Strong oxidizing agents
Storage Temperature: Room temperature, out of direct sunlight
Shelf Life: Two years from production date, if stored under recommended conditions

Exposure Controls and Personal Protection

Engineering Controls: Adequate ventilation through local exhaust or general air dilution
Respiratory Protection: Dust mask if airborne levels approach nuisance dust limits
Skin Protection: Lab coat and gloves
Eye Protection: Safety glasses with side shields
Occupational Exposure Limits: No specific limit established; follow workplace dust guidelines (typically 10 mg/m³ as total dust)
Hygiene Measures: Wash hands and exposed skin before eating or leaving work area

Physical and Chemical Properties

Appearance: White crystalline powder
Odor: Nearly odorless, faint sweet aroma
Melting Point: 151-155°C
Solubility: Soluble in water
pH (aqueous solution): 3.6-4.6
Boiling Point: Not applicable
Vapor Pressure: Not relevant at ambient temperature
Flash Point: Not flammable
Bulk Density: 0.7-0.8 g/cm³
Partition Coefficient (log Kow): Not determined
Evaporation Rate: Not applicable

Stability and Reactivity

Chemical Stability: Stable under standard environmental and storage conditions
Conditions to Avoid: Excess moisture, elevated temperature, open flames
Materials to Avoid: Strong acids or oxidizers may alter chemical structure
Decomposition Products: Fumes of carbon dioxide, carbon monoxide, and nitrogen oxides form at high temperatures
Reactivity: No hazardous polymerization expected

Toxicological Information

Acute Toxicity: Low oral toxicity, LD50 (oral, rat) estimated above 3000 mg/kg
Skin Irritation: Non-irritating in most individuals
Eye Irritation: May cause mild temporary discomfort
Sensitization: Not reported
Chronic Effects: No known chronic health effects, not listed as carcinogen or mutagen
Potential Health Effects: Repeated heavy exposure may cause digestive symptoms, liver enzymes altered after very high doses

Ecological Information

Eco-Toxicity: Not expected to be harmful to aquatic life at typical concentrations
Persistence and Degradability: Biodegradable under aerobic environmental conditions
Bioaccumulation: Potential for bioaccumulation considered low
Mobility in Soil: Readily soluble, low risk of soil accumulation
Other Adverse Effects: No additional known effects for ecosystems at recommended use levels

Disposal Considerations

Waste Treatment Methods: Dispose of contents and container according to local, regional, and national regulations
Disposal of Product: Use dedicated waste containers for organic solids, avoid release to the environment
Contaminated Packaging: Ensure packaging is free from significant product residue before recycling or disposal, follow regulatory requirements
Waste Code: Non-hazardous waste code applies to product as supplied when not contaminated with other hazardous substances

Transport Information

UN Number: Not classified for transport
Transport Hazard Class: Not regulated
Packaging Requirements: Use moisture-resistant and sealed packaging for shipment
Shipping Description: Transport as a non-hazardous material under normal road, rail, or sea shipment conditions
Special Precautions: Protect containers from physical damage, water or moisture during transport

Regulatory Information

Chemical Inventory Listed: Choline Bitartrate appears on TSCA (US), DSL (Canada), EINECS/ELINCS (EU), AICS (Australia)
Regulatory Status: Not subject to special hazard labelling or workplace restrictions; regulated as a food ingredient or dietary supplement in several regions
OSHA: Not regulated as hazardous
Other Regulations: Check local requirements for food grade or supplement use, labeling and transport
Additional Information: Observe good manufacturing and laboratory practices, ensure staff are trained in chemical handling and spill response