Material Safety Data Sheet for Chloropropanol, 98%

Identification

Product Name: Chloropropanol, 98%
Chemical Name: 3-Chloropropan-1-ol
Synonyms: 3-Chloropropanol, 1-chloro-3-hydroxypropane, gamma-chloropropanol
CAS Number: 627-30-5
EC Number: 210-990-2
Recommended Use: Laboratory chemical, industrial intermediate
Supplier: Contact sourcing department for details
Emergency Contact: Local poison control center or emergency response team

Hazard Identification

GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation), Skin Irritation, Eye Damage
Hazard Statements: Harmful if swallowed, causes severe skin burns and eye damage, may be harmful if inhaled
Signal Word: Danger
Pictograms: Corrosive, Acute toxicity
Precautionary Statements: Avoid breathing vapors, wash skin thoroughly after handling, wear protective gloves, protective clothing, eye and face protection, do not eat, drink or smoke while using
Routes of Exposure: Inhalation, skin, eye, ingestion

Composition / Information on Ingredients

Chemical Identity: 3-Chloropropan-1-ol
Concentration: ≥98%
Impurities: Water ≤1.5%, other organic compounds traces
Common Additives: None identified in analytical grade material

First Aid Measures

Inhalation: Move person to fresh air, support breathing with oxygen if needed, seek medical attention immediately
Skin Contact: Remove contaminated clothing, rinse skin under running water for minimum 15 minutes, call medical services
Eye Contact: Flush eyes with water for at least 15 minutes, keep eyelids open, remove contact lenses if present, seek immediate medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, never give anything by mouth to unconscious person, seek urgent medical attention

Fire-Fighting Measures

Suitable Extinguishing Media: Foam, dry chemical powder, carbon dioxide, water spray for large fires
Unsuitable Media: Direct water jet due to risk of chemical run-off
Hazards: Emits hydrogen chloride and carbon oxides fumes in fire
Protective Equipment: Self-contained breathing apparatus, chemical-resistant suit, heat-resistant gloves
Special Procedures: Isolate area, remove combustible materials, cool containers with water spray to prevent explosion

Accidental Release Measures

Personal Protection: Don chemical splash goggles, gloves, protective clothing, and supplied-air respirator in case of large release
Environmental Precautions: Prevent entry into drains, surface water, and soil
Cleanup Methods: Absorb with inert material (sand, earth), transfer to chemical waste containers, ventilate area, wash spill site after cleanup
Notification Requirements: Report major spills to local authorities as required

Handling and Storage

Handling: Work in well-ventilated fume hood, keep container tightly closed, avoid all skin and eye contact, do not breathe mist or vapor
Storage: Store in tightly sealed containers, away from incompatible chemicals (strong oxidizers, alkalis, reducing agents), keep material in a cool, dry, corrosion-resistant cabinet, label storage area clearly
Other Precautions: Restrict access to trained staff, post hazard warning signs, check regularly for leaks

Exposure Controls and Personal Protection

Exposure Limits: No established national exposure limit values; recommend keeping airborne concentrations below 5 ppm
Engineering Controls: Use local exhaust ventilation and chemical fume hood
Personal Protection: Nitrile or butyl rubber gloves, lab coat, splash-proof goggles, face shield, approved respirator for vapor/aerosol
Hygiene Measures: Remove contaminated clothing, wash hands before breaks and after work, do not eat or smoke in work area
Environmental Controls: Filter exhaust streams, monitor air quality in storage and work sites

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Sharp, pungent smell, reminiscent of organic solvents
pH: Not applicable (liquid, neutral solution ~6-7)
Melting Point: -41°C
Boiling Point: 156°C
Flash Point: 70°C (closed cup)
Evaporation Rate: Data not available
Flammability: Not highly flammable but can sustain combustion above flash point
Auto-ignition Temperature: 380°C
Vapor Pressure: 0.7 mmHg at 20°C
Solubility: Miscible with water and most polar organic solvents
Density: 1.16 g/cm³ at 20°C
Viscosity: Low, flows easily
Partition Coefficient (log Kow): -0.86

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: High temperatures, ignition sources, moisture exposure
Materials to Avoid: Strong oxidizing agents, strong bases, reducing agents, alkali metals
Hazardous Decomposition: Hydrogen chloride, carbon oxides (CO, CO₂), toxic fumes
Polymerization: Will not occur under normal conditions

Toxicological Information

Acute Toxicity: Oral LD50 (rat): 207 mg/kg, inhalation LC50: not precisely determined, skin LD50 (rabbit): moderate
Skin Corrosion/Irritation: Causes severe burning, redness, blistering
Eye Damage/Irritation: High risk of permanent damage, pain, tearing, vision impairment
Respiratory Sensitization: May trigger coughing, shortness of breath, upper airway irritation
Chronic Effects: Prolonged exposure may affect nervous system, liver, kidneys
Carcinogenicity/Mutagenicity:** No clear evidence in commercial formulations but precaution advised for all halogenated compounds