Product Name: Chlorhexidine Digluconate Solution
Chemical Formula: C22H30Cl2N10 · 2C6H12O7
Synonyms: 1,1'-Hexamethylenebis[5-(p-chlorophenyl)biguanide] digluconate
CAS Number: 18472-51-0
Intended Use: Topical antiseptic, disinfectant in healthcare, dental, and veterinary practice
Manufacturer Contact: Name, Address, Emergency Phone, Business Phone (Person-in-charge indicated for chemical emergencies, not routine inquiries)
GHS Classification: Skin Irritant (Category 2), Serious Eye Damage (Category 1), Acute Toxicity Oral (Category 4), Aquatic Chronic (Category 2)
Signal Word: Danger
Hazard Statements: Causes serious eye damage. Causes skin irritation. Harmful if swallowed. Toxic to aquatic life with long lasting effects.
Pictograms: Corrosive, Exclamation mark, Environment
Precautionary Statements: Avoid contact with skin and eyes. Wear protective gloves, clothing, eye and face protection. Prevent release to the environment.
Active Ingredient: Chlorhexidine Digluconate
Concentration: 20% w/v aqueous solution typical (range 5–20% as per supplier)
Other Components: Water (purified), trace process residues
Impurities: Unlikely to contain significant concentrations of hazardous impurities
Component CAS Numbers: Chlorhexidine Digluconate (18472-51-0), Water (7732-18-5)
Inhalation: Remove to fresh air, seek medical advice if symptoms develop such as coughing, shortness of breath, or sore throat.
Skin Contact: Remove contaminated clothing, flush skin with plenty of water, wash with soap, seek medical attention if irritation persists.
Eye Contact: Irrigate with running water for at least fifteen minutes, lifting upper and lower lids, seek immediate medical attention.
Ingestion: Rinse mouth, do not induce vomiting, seek urgent medical attention, show medical personnel this safety data.
Delayed Symptoms: Redness, blistering, burns, persistent pain may develop requiring ongoing treatment.
Suitable Extinguishing Media: Use water spray, foam, dry powder, or carbon dioxide. Do not use water jets directly onto liquid as it spreads possible contamination.
Specific Hazards from Fire: Toxic fumes of hydrogen chloride, nitrogen oxides, and carbon oxides release during combustion.
Protective Equipment: Full protective gear with self-contained breathing apparatus.
Advice for Firefighters: Cool containers exposed to flames with water spray, prevent contaminated extinguishing water from entering drains or watercourses.
Personal Precautions: Use chemical-resistant gloves, safety goggles or face shield, laboratory coat, and work in well-ventilated areas.
Environmental Precautions: Block entry to drains, surface water, and soil; contain spill with absorbent sand or inert material.
Clean-up Methods: Scoop liquid into a marked, chemical waste container; wash spill site with water and detergent; ventilate area after completion.
Decontamination: Disinfect tools and surfaces after cleanup.
Handling: Keep away from eyes, skin, and clothing. Avoid inhaling vapors, mist, or spray. Do not eat, drink, or smoke during use. Ensure adequate ventilation. Wear suitable protective equipment.
Storage: Store in cool, dry place at below 25°C, in tightly closed containers, away from direct sunlight, oxidizers, acids, and food. Keep away from children. Follow regulatory labeling for storage.
Compatible Materials: Avoid storage with strong acids, anionic compounds, or oxidants.
Occupational Exposure Limits: Not established for chlorhexidine digluconate; apply general workplace exposure limits for irritants.
Engineering Controls: General or local exhaust ventilation recommended. Use eyewash fountains and safety showers.
Personal Protective Equipment: Chemical-resistant nitrile or neoprene gloves, safety goggles, lab coats, and suitable respiratory protection in poorly ventilated spaces.
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing promptly.
Appearance: Clear or slightly yellow, viscous aqueous liquid
Odor: Mild, characteristic odor
pH: 5.0–7.0
Boiling Point: ~100°C
Melting Point: Not applicable
Relative Density: 1.06–1.08 g/mL at 20°C
Solubility: Soluble in water
Vapor Pressure: Negligible
Viscosity: Moderate
Flash Point: Not flammable
Partition Coefficient: Not determined
Other Data: Decomposes under extreme heat
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: No hazardous reactions under normal use
Incompatible Materials: Strong oxidizing agents, anionic soaps, and detergents
Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon oxides released by thermal decomposition
Hazardous Polymerization: Does not occur
Acute Toxicity: Harmful if swallowed; human ingestion linked with gastrointestinal irritation, nausea, vomiting
Skin Corrosion/Irritation: Irritant, may cause dermatitis on prolonged or repeated contact
Serious Eye Damage/Irritation: Severe eye irritant, risk of corneal injury
Respiratory or Skin Sensitization: Allergic skin and rare respiratory responses recorded
Repeated Dose Toxicity: No evidence for specific target organ toxicity from regular workplace exposure
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: No reliable evidence for mutagenic effects at normal exposure definitions
Reproductive Toxicity: Reproductive effects not documented at expected dose levels
Toxicity to Aquatic Life: Highly toxic to fish and invertebrates
Persistence and Degradability: Expected to be persistent in water and sediment
Bioaccumulation Potential: Low potential documented due to low partition coefficient
Mobility in Soil: Water-soluble, may migrate into groundwater if released in large quantities
Other Adverse Effects: Use large quantities with care to prevent environmental contamination; do not discharge into natural waterways
Waste Disposal Methods: Collect in labeled, sealed containers for hazardous waste disposal. Dispose by incineration in licensed chemical incinerator or through authorized chemical waste contractors following local, regional, and national regulations.
Contaminated Packaging: Triple rinse before recycling or disposal; comply with local waste disposal requirements.
Precautions: Do not allow entry into drains, watercourses, or soil. Do not mix with other waste streams.
UN Number: Not regulated in typical concentrations and volumes; check for local exceptions
ADR/RID, IMDG, IATA Classification: May not require classification, but large quantities could trigger special handling and marking; emergency guidance code applies if classified
Proper Shipping Name: Chlorhexidine digluconate solution
Hazard Labels: Not required at typical concentrations
Packing Group: None assigned at routine use concentrations
Special Precautions: Avoid loading with strong oxidizers and foodstuffs
TSCA Inventory Status: Listed
DSL/NDSL (Canada): Listed
EU Classification: Xi (Irritant), N (Dangerous for the environment)
Hazard Symbols: Irritant, Environmental hazardous
REACH Status: Exempt or pre-registered for healthcare use
Workplace Exposure Regulation: Subject to control under local occupational exposure code of practice
Other Standards: Conforms with requirements for use in biocidal, antiseptic, and disinfectant products under applicable regional laws
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